CV set Entry Protein names Organism Octapeptide Gene ontology (cellular component) Gene ontology (biological process) Gene ontology (molecular function) Gene ontology IDs Cross-reference (Pfam) Cross-reference (InterPro) 0 Q9VLL3 A-kinase anchor protein 200 Drosophila melanogaster (Fruit fly) GGSGSRLS cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; plasma membrane [GO:0005886] behavioral response to ethanol [GO:0048149]; cellular response to ethanol [GO:0071361]; circadian rhythm [GO:0007623]; germ cell development [GO:0007281]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of protein localization to membrane [GO:1905477]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249] actin filament binding [GO:0051015]; Notch binding [GO:0005112]; protein kinase A regulatory subunit binding [GO:0034237] GO:0005112; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0007281; GO:0007623; GO:0032956; GO:0034237; GO:0045747; GO:0048149; GO:0051015; GO:0071361; GO:1905477; GO:2000249 0 P0CM16 ADP-ribosylation factor Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) GKQNSKLK Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886] intracellular protein transport [GO:0006886]; vesicle-mediated transport [GO:0016192] GTP binding [GO:0005525] GO:0005525; GO:0005794; GO:0005886; GO:0006886; GO:0016192 PF00025; IPR027417;IPR005225;IPR006689; 0 P34727 ADP-ribosylation factor Ajellomyces capsulatus (Darling's disease fungus) (Histoplasma capsulatum) GAKTSKLS Golgi apparatus [GO:0005794] protein transport [GO:0015031]; vesicle-mediated transport [GO:0016192] GTP binding [GO:0005525] GO:0005525; GO:0005794; GO:0015031; GO:0016192 PF00025; IPR027417;IPR005225;IPR006689; 0 P11076 ADP-ribosylation factor 1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) GKSLSHLP cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; plasma membrane [GO:0005886] endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi to plasma membrane transport [GO:0006893]; intracellular protein transport [GO:0006886]; macroautophagy [GO:0016236]; vesicle-mediated transport [GO:0016192] GTPase activity [GO:0003924]; GTP binding [GO:0005525] GO:0003924; GO:0005525; GO:0005794; GO:0005829; GO:0005886; GO:0006886; GO:0006888; GO:0006893; GO:0016192; GO:0016236 PF00025; IPR027417;IPR005225;IPR006689; 0 P18085 ADP-ribosylation factor 4 Homo sapiens (Human) GPRCSKLS cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587] activation of phospholipase D activity [GO:0031584]; apical protein localization [GO:0045176]; brain development [GO:0007420]; cell migration [GO:0016477]; cilium assembly [GO:0060271]; dendritic spine development [GO:0060996]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment or maintenance of epithelial cell apical/basal polarity [GO:0045197]; intracellular protein transport [GO:0006886]; learning [GO:0007612]; negative regulation of apoptotic process [GO:0043066]; positive regulation of transcription by RNA polymerase II [GO:0045944]; protein ADP-ribosylation [GO:0006471]; protein localization to cilium [GO:0061512]; regulation of postsynapse organization [GO:0099175]; regulation of reactive oxygen species metabolic process [GO:2000377]; response to axon injury [GO:0048678]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192] epidermal growth factor receptor binding [GO:0005154]; GTP binding [GO:0005525] GO:0005154; GO:0005525; GO:0005794; GO:0005829; GO:0005886; GO:0006471; GO:0006886; GO:0006888; GO:0006890; GO:0007173; GO:0007420; GO:0007612; GO:0016020; GO:0016192; GO:0016477; GO:0031584; GO:0032587; GO:0043066; GO:0043197; GO:0045176; GO:0045197; GO:0045944; GO:0048678; GO:0060271; GO:0060996; GO:0061512; GO:0070062; GO:0098978; GO:0099175; GO:2000377 PF00025; IPR027417;IPR005225;IPR006689; 0 P62330 ADP-ribosylation factor 6 Homo sapiens (Human) GCSVSKKK cell cortex [GO:0005938]; cleavage furrow [GO:0032154]; cytosol [GO:0005829]; early endosome membrane [GO:0031901]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; filopodium membrane [GO:0031527]; Flemming body [GO:0090543]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; membrane [GO:0016020]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; recycling endosome membrane [GO:0055038]; ruffle [GO:0001726] cell adhesion [GO:0007155]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell division [GO:0051301]; cellular response to nerve growth factor stimulus [GO:1990090]; cortical actin cytoskeleton organization [GO:0030866]; endocytic recycling [GO:0032456]; establishment of epithelial cell polarity [GO:0090162]; hepatocyte apoptotic process [GO:0097284]; intracellular protein transport [GO:0006886]; liver development [GO:0001889]; maintenance of postsynaptic density structure [GO:0099562]; myeloid cell apoptotic process [GO:0033028]; negative regulation of dendrite development [GO:2000171]; negative regulation of protein localization to cell surface [GO:2000009]; negative regulation of receptor-mediated endocytosis [GO:0048261]; nervous system development [GO:0007399]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of focal adhesion disassembly [GO:0120183]; positive regulation of keratinocyte migration [GO:0051549]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein secretion [GO:0050714]; protein localization to cell surface [GO:0034394]; protein localization to endosome [GO:0036010]; regulation of dendritic spine development [GO:0060998]; regulation of filopodium assembly [GO:0051489]; regulation of presynapse assembly [GO:1905606]; regulation of Rac protein signal transduction [GO:0035020]; ruffle assembly [GO:0097178]; synaptic vesicle endocytosis [GO:0048488]; vesicle-mediated transport [GO:0016192] GDP binding [GO:0019003]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; protein N-terminus binding [GO:0047485]; thioesterase binding [GO:0031996] GO:0001726; GO:0001889; GO:0003924; GO:0005525; GO:0005768; GO:0005794; GO:0005829; GO:0005886; GO:0005925; GO:0005938; GO:0006886; GO:0007049; GO:0007155; GO:0007399; GO:0016020; GO:0016192; GO:0019003; GO:0030139; GO:0030154; GO:0030838; GO:0030866; GO:0031527; GO:0031901; GO:0031996; GO:0032154; GO:0032456; GO:0033028; GO:0034394; GO:0035020; GO:0036010; GO:0047485; GO:0048261; GO:0048488; GO:0050714; GO:0051301; GO:0051489; GO:0051549; GO:0055038; GO:0060998; GO:0070062; GO:0090162; GO:0090543; GO:0097178; GO:0097284; GO:0098793; GO:0098978; GO:0099562; GO:0120183; GO:1903078; GO:1905606; GO:1990090; GO:2000009; GO:2000171 PF00025; IPR041838;IPR027417;IPR005225;IPR006689; 0 Q05175 Brain acid soluble protein 1 (22 kDa neuronal tissue-enriched acidic protein) (Neuronal axonal membrane protein NAP-22) Rattus norvegicus (Rat) GSENSALK chromatin [GO:0000785]; cytoplasm [GO:0005737]; growth cone [GO:0030426]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605] glomerular visceral epithelial cell differentiation [GO:0072112]; negative regulation of transcription, DNA-templated [GO:0045892] calmodulin binding [GO:0005516]; protein domain specific binding [GO:0019904]; transcription corepressor activity [GO:0003714]; transcription regulatory region sequence-specific DNA binding [GO:0000976] GO:0000785; GO:0000976; GO:0003714; GO:0005516; GO:0005634; GO:0005737; GO:0005886; GO:0016363; GO:0016605; GO:0016607; GO:0019904; GO:0030426; GO:0045892; GO:0072112 PF05466; IPR008408; 0 P80723 Brain acid soluble protein 1 (22 kDa neuronal tissue-enriched acidic protein) (Neuronal axonal membrane protein NAP-22) Homo sapiens (Human) GTTTSHPA cell junction [GO:0030054]; chromatin [GO:0000785]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular exosome [GO:0070062]; growth cone [GO:0030426]; nuclear matrix [GO:0016363]; nuclear speck [GO:0016607]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; PML body [GO:0016605]; vesicle [GO:0031982] diaphragm development [GO:0060539]; glomerular visceral epithelial cell differentiation [GO:0072112]; gonad development [GO:0008406]; mesenchymal to epithelial transition [GO:0060231]; metanephric mesenchyme development [GO:0072075]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of heart growth [GO:0060421]; positive regulation of metanephric ureteric bud development [GO:2001076]; substantia nigra development [GO:0021762]; thorax and anterior abdomen determination [GO:0007356] protein domain specific binding [GO:0019904]; transcription corepressor activity [GO:0003714]; transcription regulatory region sequence-specific DNA binding [GO:0000976] GO:0000785; GO:0000976; GO:0003714; GO:0005634; GO:0005737; GO:0005856; GO:0005886; GO:0007356; GO:0008406; GO:0016363; GO:0016605; GO:0016607; GO:0019904; GO:0021762; GO:0030054; GO:0030426; GO:0031982; GO:0045892; GO:0060231; GO:0060421; GO:0060539; GO:0070062; GO:0072075; GO:0072112; GO:2001076 PF05466; IPR008408; 0 Q99653 Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22) Homo sapiens (Human) GGQCSSLS cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; Golgi membrane [GO:0000139]; microtubule cytoskeleton [GO:0015630]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133] cellular response to acidic pH [GO:0071468]; cytoplasmic microtubule organization [GO:0031122]; hyaluronan catabolic process [GO:0030214]; membrane docking [GO:0022406]; membrane fusion [GO:0061025]; membrane organization [GO:0061024]; microtubule bundle formation [GO:0001578]; negative regulation of calcineurin-NFAT signaling cascade [GO:0070885]; negative regulation of NF-kappaB transcription factor activity [GO:0032088]; negative regulation of phosphatase activity [GO:0010923]; negative regulation of protein autophosphorylation [GO:0031953]; negative regulation of protein import into nucleus [GO:0042308]; negative regulation of protein kinase activity [GO:0006469]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of protein ubiquitination [GO:0031397]; positive regulation of phospholipid biosynthetic process [GO:0071073]; positive regulation of protein glycosylation [GO:0060050]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of protein transport [GO:0051222]; positive regulation of sodium:proton antiporter activity [GO:0032417]; potassium ion transport [GO:0006813]; protein complex oligomerization [GO:0051259]; protein export from nucleus [GO:0006611]; protein stabilization [GO:0050821]; regulation of intracellular pH [GO:0051453]; regulation of neuron death [GO:1901214]; small GTPase mediated signal transduction [GO:0007264]; vesicle fusion [GO:0006906]; vesicle targeting [GO:0006903] calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; kinase binding [GO:0019900]; microtubule binding [GO:0008017]; potassium channel regulator activity [GO:0015459]; protein kinase inhibitor activity [GO:0004860] GO:0000139; GO:0001578; GO:0001933; GO:0004860; GO:0005509; GO:0005634; GO:0005737; GO:0005783; GO:0005793; GO:0005829; GO:0005886; GO:0005925; GO:0006469; GO:0006611; GO:0006813; GO:0006903; GO:0006906; GO:0007264; GO:0008017; GO:0010923; GO:0015459; GO:0015630; GO:0019900; GO:0022406; GO:0030133; GO:0030214; GO:0031122; GO:0031397; GO:0031953; GO:0032088; GO:0032417; GO:0042308; GO:0048306; GO:0050821; GO:0051222; GO:0051259; GO:0051453; GO:0060050; GO:0061024; GO:0061025; GO:0070062; GO:0070885; GO:0071073; GO:0071468; GO:0090314; GO:1901214 PF13499; IPR011992;IPR002048; 0 O81223 Calcineurin B-like protein 4 (Protein SALT OVERLY SENSITIVE 3) Arabidopsis thaliana (Mouse-ear cress) GDSASKVI calcineurin complex [GO:0005955]; cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886] cellular potassium ion homeostasis [GO:0030007]; detection of calcium ion [GO:0005513]; hypotonic salinity response [GO:0042539] calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calcium ion binding [GO:0005509] GO:0004723; GO:0005509; GO:0005513; GO:0005634; GO:0005737; GO:0005886; GO:0005955; GO:0030007; GO:0042539 PF13202;PF13499; IPR011992;IPR002048; 0 Q99828 Calcium and integrin-binding protein 1 (CIB) (Calcium- and integrin-binding protein) (CIBP) (Calmyrin) (DNA-PKcs-interacting protein) (Kinase-interacting protein) (KIP) (SNK-interacting protein 2-28) (SIP2-28) Homo sapiens (Human) GSKLSKKK apical plasma membrane [GO:0016324]; cell periphery [GO:0071944]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; filopodium tip [GO:0032433]; Golgi apparatus [GO:0005794]; growth cone [GO:0030426]; lamellipodium [GO:0030027]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; sarcolemma [GO:0042383]; vesicle [GO:0031982] angiogenesis [GO:0001525]; apoptotic process [GO:0006915]; cell adhesion [GO:0007155]; cell division [GO:0051301]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to growth factor stimulus [GO:0071363]; cellular response to nerve growth factor stimulus [GO:1990090]; cellular response to tumor necrosis factor [GO:0071356]; cytoplasmic microtubule organization [GO:0031122]; double-strand break repair [GO:0006302]; endomitotic cell cycle [GO:0007113]; extrinsic apoptotic signaling pathway [GO:0097191]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of megakaryocyte differentiation [GO:0045653]; negative regulation of microtubule depolymerization [GO:0007026]; negative regulation of neuron projection development [GO:0010977]; negative regulation of protein kinase B signaling [GO:0051898]; negative regulation of protein phosphorylation [GO:0001933]; platelet formation [GO:0030220]; positive regulation of calcineurin-NFAT signaling cascade [GO:0070886]; positive regulation of catalytic activity [GO:0043085]; positive regulation of cell adhesion mediated by integrin [GO:0033630]; positive regulation of cell growth [GO:0030307]; positive regulation of cell-matrix adhesion [GO:0001954]; positive regulation of cell migration [GO:0030335]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of male germ cell proliferation [GO:2000256]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; regulation of cell division [GO:0051302]; regulation of cell population proliferation [GO:0042127]; response to ischemia [GO:0002931]; spermatid development [GO:0007286]; thrombopoietin-mediated signaling pathway [GO:0038163] calcium-dependent protein kinase inhibitor activity [GO:0008427]; calcium ion binding [GO:0005509]; ion channel binding [GO:0044325]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein-membrane adaptor activity [GO:0043495]; protein serine/threonine kinase inhibitor activity [GO:0030291]; small GTPase binding [GO:0031267] GO:0001525; GO:0001933; GO:0001934; GO:0001954; GO:0002931; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005783; GO:0005794; GO:0005813; GO:0005886; GO:0006302; GO:0006915; GO:0006974; GO:0007026; GO:0007113; GO:0007155; GO:0007286; GO:0008022; GO:0008284; GO:0008285; GO:0008427; GO:0010977; GO:0016020; GO:0016324; GO:0019901; GO:0030027; GO:0030220; GO:0030291; GO:0030307; GO:0030335; GO:0030425; GO:0030426; GO:0031122; GO:0031267; GO:0031982; GO:0032433; GO:0032587; GO:0033630; GO:0038163; GO:0042127; GO:0042383; GO:0043005; GO:0043025; GO:0043066; GO:0043085; GO:0043204; GO:0043495; GO:0044325; GO:0045653; GO:0048471; GO:0051092; GO:0051301; GO:0051302; GO:0051898; GO:0070062; GO:0070374; GO:0070886; GO:0071356; GO:0071363; GO:0071902; GO:0071944; GO:0090050; GO:0090314; GO:0097191; GO:1900026; GO:1903078; GO:1990090; GO:2000256 PF13499; IPR011992;IPR018247;IPR002048; 0 Q06389 Calcium-binding protein NCS-1 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) GLSPSAPA cellular bud membrane [GO:0033101]; cytosol [GO:0005829]; Golgi membrane [GO:0000139] positive regulation of 1-phosphatidylinositol 4-kinase activity [GO:0043128]; regulation of signal transduction [GO:0009966] calcium ion binding [GO:0005509]; enzyme activator activity [GO:0008047] GO:0000139; GO:0005509; GO:0005829; GO:0008047; GO:0009966; GO:0033101; GO:0043128 PF13499;PF13833; IPR011992;IPR018247;IPR002048;IPR028846; 0 Q09711 Calcium-binding protein NCS-1 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) GACISKNS cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] calcium-mediated signaling using intracellular calcium source [GO:0035584]; negative regulation of calcium ion import across plasma membrane [GO:1905949]; sporulation resulting in formation of a cellular spore [GO:0030435] 1-phosphatidylinositol 4-kinase activator activity [GO:0098744]; calcium ion binding [GO:0005509] GO:0005509; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0030435; GO:0035584; GO:0098744; GO:1905949 PF00036;PF13499; IPR011992;IPR018247;IPR002048;IPR028846; 0 Q99618 Cell division cycle-associated protein 3 (Gene-rich cluster protein C8) (Trigger of mitotic entry protein 1) (TOME-1) Homo sapiens (Human) GSCCSCPD adherens junction [GO:0005912]; cytosol [GO:0005829] cell cycle [GO:0007049]; cell division [GO:0051301]; protein ubiquitination [GO:0016567] GO:0005829; GO:0005912; GO:0007049; GO:0016567; GO:0051301 IPR038832; 0 Q8MMZ7 cGMP-dependent protein kinase (EC 2.7.11.12) (TgPKG) Toxoplasma gondii GARCSKFS apical plasma membrane [GO:0016324]; cytoplasm [GO:0005737]; plasma membrane [GO:0005886] positive regulation of cell motility [GO:2000147]; protein phosphorylation [GO:0006468] ATP binding [GO:0005524]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0004692; GO:0005524; GO:0005737; GO:0005886; GO:0006468; GO:0016324; GO:0030553; GO:0046872; GO:0106310; GO:0106311; GO:2000147 PF00027;PF00069; IPR000961;IPR018490;IPR018488;IPR000595;IPR011009;IPR000719;IPR017441;IPR014710;IPR008271;IPR035014; 0 Q8WU20 Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (FGFR-signaling adaptor SNT) (Suc1-associated neurotrophic factor target 1) (SNT-1) Homo sapiens (Human) GCEVSKLS adherens junction [GO:0005912]; cytosol [GO:0005829]; endomembrane system [GO:0012505]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; plasma membrane [GO:0005886] activation of MAPK activity [GO:0000187]; activation of MAPKK activity [GO:0000186]; anterior/posterior axis specification, embryo [GO:0008595]; axon guidance [GO:0007411]; fibroblast growth factor receptor signaling pathway [GO:0008543]; forebrain development [GO:0030900]; gastrulation with mouth forming second [GO:0001702]; G protein-coupled receptor signaling pathway [GO:0007186]; lens fiber cell development [GO:0070307]; MAPK cascade [GO:0000165]; negative regulation of cardiac muscle cell differentiation [GO:2000726]; neuroblast proliferation [GO:0007405]; neurotrophin TRK receptor signaling pathway [GO:0048011]; optic placode formation involved in camera-type eye formation [GO:0046619]; organ induction [GO:0001759]; positive regulation of protein kinase B signaling [GO:0051897]; prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis [GO:0060527]; regulation of apoptotic process [GO:0042981]; regulation of epithelial cell proliferation [GO:0050678]; regulation of ERK1 and ERK2 cascade [GO:0070372]; transmembrane receptor protein tyrosine phosphatase signaling pathway [GO:0007185]; ventricular septum development [GO:0003281] fibroblast growth factor receptor binding [GO:0005104]; neurotrophin TRKA receptor binding [GO:0005168]; phosphatase activator activity [GO:0019211]; transmembrane receptor protein tyrosine kinase adaptor activity [GO:0005068] GO:0000165; GO:0000186; GO:0000187; GO:0001702; GO:0001759; GO:0003281; GO:0005068; GO:0005104; GO:0005168; GO:0005829; GO:0005886; GO:0005887; GO:0005912; GO:0007185; GO:0007186; GO:0007405; GO:0007411; GO:0008543; GO:0008595; GO:0012505; GO:0016020; GO:0019211; GO:0030900; GO:0042981; GO:0046619; GO:0048011; GO:0050678; GO:0051897; GO:0060527; GO:0070307; GO:0070372; GO:2000726 PF02174; IPR038742;IPR002404; 0 P05961 Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Transframe peptide (TF); p6-pol (p6*); Protease (EC 3.4.23.16) (PR) (Retropepsin); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (p66 RT); p51 RT; p15; Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)] Human immunodeficiency virus type 1 group M subtype B (isolate MN) (HIV-1) GSSTSTPA host cell nucleus [GO:0042025]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; viral nucleocapsid [GO:0019013]; virion membrane [GO:0055036] DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process [GO:0039651]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral penetration into host nucleus [GO:0075732] aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; exoribonuclease H activity [GO:0004533]; lipid binding [GO:0008289]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0004533; GO:0005198; GO:0006310; GO:0008270; GO:0008289; GO:0015074; GO:0019013; GO:0020002; GO:0039651; GO:0039657; GO:0042025; GO:0044826; GO:0046718; GO:0055036; GO:0072494; GO:0075713; GO:0075732 PF00540;PF00607;PF00552;PF02022;PF00075;PF00665;PF00077;PF00078;PF06815;PF06817;PF00098; IPR001969;IPR043502;IPR000721;IPR017856;IPR036862;IPR001037;IPR001584;IPR003308;IPR000071;IPR012344;IPR001995;IPR021109;IPR034170;IPR018061;IPR008916;IPR008919;IPR010999;IPR043128;IPR012337;IPR002156;IPR036397;IPR000477;IPR010659;IPR010661;IPR001878;IPR036875; 0 Q22663 Globin-like protein 26 Caenorhabditis elegans GLFASKLF cytoplasm [GO:0005737]; membrane [GO:0016020]; nuclear lamina [GO:0005652]; plasma membrane [GO:0005886] heme binding [GO:0020037]; metal ion binding [GO:0046872]; oxygen binding [GO:0019825]; oxygen carrier activity [GO:0005344] GO:0005344; GO:0005652; GO:0005737; GO:0005886; GO:0016020; GO:0019825; GO:0020037; GO:0046872 PF00042; IPR000971;IPR009050;IPR012292;IPR044399; 0 Q9H4G4 Golgi-associated plant pathogenesis-related protein 1 (GAPR-1) (Golgi-associated PR-1 protein) (Glioma pathogenesis-related protein 2) (GliPR 2) Homo sapiens (Human) GSRASTLL extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139] positive regulation of epithelial cell migration [GO:0010634]; positive regulation of epithelial to mesenchymal transition [GO:0010718]; positive regulation of ERK1 and ERK2 cascade [GO:0070374] protein homodimerization activity [GO:0042803] GO:0000139; GO:0005615; GO:0010634; GO:0010718; GO:0042803; GO:0070062; GO:0070374 PF00188; IPR018244;IPR014044;IPR035940;IPR001283;IPR034113; 0 P37235 Hippocalcin-like protein 1 (Calcium-binding protein BDR-1) (HLP2) (Visinin-like protein 3) (VILIP-3) Homo sapiens (Human) GLTISSLF membrane [GO:0016020] calcium ion binding [GO:0005509] GO:0005509; GO:0016020 PF13499;PF13833; IPR011992;IPR018247;IPR002048;IPR028846; 0 P53701 Holocytochrome c-type synthase (EC 4.4.1.17) (Cytochrome c-type heme lyase) Homo sapiens (Human) GLSVSKLL membrane [GO:0016020]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739] animal organ morphogenesis [GO:0009887]; cytochrome c-heme linkage [GO:0018063] heme binding [GO:0020037]; holocytochrome-c synthase activity [GO:0004408]; metal ion binding [GO:0046872] GO:0004408; GO:0005739; GO:0005743; GO:0009887; GO:0016020; GO:0018063; GO:0020037; GO:0046872 PF01265; IPR000511; 0 Q9D6Y7 Mitochondrial peptide methionine sulfoxide reductase (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase) (Protein-methionine-S-oxide reductase) (PMSR) Mus musculus (Mouse) GSNKSKPK actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] aging [GO:0007568]; cellular response to oxidative stress [GO:0034599] L-methionine-(S)-S-oxide reductase activity [GO:0036456]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113] GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0007568; GO:0008113; GO:0015629; GO:0034599; GO:0036456 PF01625; IPR002569;IPR036509; 0 P42325 Neurocalcin homolog (DrosNCa) Drosophila melanogaster (Fruit fly) GKSNSKLK negative regulation of neuronal signal transduction [GO:1902848]; positive regulation of circadian sleep/wake cycle, sleep [GO:0045938] calcium ion binding [GO:0005509] GO:0005509; GO:0045938; GO:1902848 PF13499;PF13833; IPR011992;IPR018247;IPR002048;IPR028846; 0 P62166 Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein) Homo sapiens (Human) GSAKSVPV calyx of Held [GO:0044305]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dense core granule [GO:0031045]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic cytosol [GO:0099524]; postsynaptic density [GO:0014069]; presynaptic cytosol [GO:0099523] phosphatidylinositol-mediated signaling [GO:0048015]; positive regulation of exocytosis [GO:0045921]; regulation of neuron projection development [GO:0010975]; regulation of synaptic vesicle exocytosis [GO:2000300] calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; protein kinase binding [GO:0019901]; voltage-gated calcium channel activity [GO:0005245]; voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels [GO:0099626] GO:0000287; GO:0005245; GO:0005509; GO:0005737; GO:0005794; GO:0005886; GO:0010975; GO:0014069; GO:0019901; GO:0030425; GO:0031045; GO:0043231; GO:0044305; GO:0045921; GO:0048015; GO:0048471; GO:0098978; GO:0099523; GO:0099524; GO:0099626; GO:2000300 PF00036;PF13499; IPR011992;IPR018247;IPR002048;IPR028846; 0 Q65200 Protein E248R (pE248R) African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV) GSCCSCLK host cell membrane [GO:0033644]; integral component of membrane [GO:0016021]; viral inner membrane [GO:0039641]; virion [GO:0019012] GO:0016021; GO:0019012; GO:0033644; GO:0039641 PF02442; IPR003472; 0 Q8IZE3 Protein-associating with the carboxyl-terminal domain of ezrin (Ezrin-binding protein PACE-1) (SCY1-like protein 3) Homo sapiens (Human) GGSTSKNS cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; lamellipodium [GO:0030027] cell migration [GO:0016477]; cellular protein localization [GO:0034613]; inflammatory response [GO:0006954]; neuron development [GO:0048666]; protein phosphorylation [GO:0006468]; spinal cord motor neuron differentiation [GO:0021522] ATP binding [GO:0005524]; identical protein binding [GO:0042802] GO:0000139; GO:0005524; GO:0005737; GO:0005794; GO:0006468; GO:0006954; GO:0016477; GO:0021522; GO:0030027; GO:0034613; GO:0042802; GO:0048666 IPR011989;IPR016024;IPR021133;IPR011009;IPR000719; 0 P12931 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src) Homo sapiens (Human) GKSASKQF actin filament [GO:0005884]; caveola [GO:0005901]; cell junction [GO:0030054]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; late endosome [GO:0005770]; lysosome [GO:0005764]; membrane raft [GO:0045121]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; podosome [GO:0002102]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091]; ruffle membrane [GO:0032587] activation of protein kinase B activity [GO:0032148]; adherens junction organization [GO:0034332]; angiotensin-activated signaling pathway involved in heart process [GO:0086098]; axon guidance [GO:0007411]; bone resorption [GO:0045453]; branching involved in mammary gland duct morphogenesis [GO:0060444]; cell adhesion [GO:0007155]; cell-cell adhesion [GO:0098609]; cell cycle [GO:0007049]; cell differentiation [GO:0030154]; cell population proliferation [GO:0008283]; cellular response to fatty acid [GO:0071398]; cellular response to fluid shear stress [GO:0071498]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to hypoxia [GO:0071456]; cellular response to insulin stimulus [GO:0032869]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to progesterone stimulus [GO:0071393]; entry of bacterium into host cell [GO:0035635]; ephrin receptor signaling pathway [GO:0048013]; epidermal growth factor receptor signaling pathway [GO:0007173]; ERBB2 signaling pathway [GO:0038128]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; focal adhesion assembly [GO:0048041]; forebrain development [GO:0030900]; G protein-coupled receptor signaling pathway [GO:0007186]; innate immune response [GO:0045087]; integrin-mediated signaling pathway [GO:0007229]; interleukin-6-mediated signaling pathway [GO:0070102]; intestinal epithelial cell development [GO:0060576]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; macroautophagy [GO:0016236]; negative regulation of anoikis [GO:2000811]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0043154]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of intrinsic apoptotic signaling pathway [GO:2001243]; negative regulation of mitochondrial depolarization [GO:0051902]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of telomerase activity [GO:0051974]; negative regulation of telomere maintenance via telomerase [GO:0032211]; negative regulation of transcription, DNA-templated [GO:0045892]; neurotrophin TRK receptor signaling pathway [GO:0048011]; odontogenesis [GO:0042476]; oogenesis [GO:0048477]; osteoclast development [GO:0036035]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of apoptotic process [GO:0043065]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737]; positive regulation of cytokine production [GO:0001819]; positive regulation of dephosphorylation [GO:0035306]; positive regulation of DNA biosynthetic process [GO:2000573]; positive regulation of epithelial cell migration [GO:0010634]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of glucose metabolic process [GO:0010907]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of integrin activation [GO:0033625]; positive regulation of lamellipodium morphogenesis [GO:2000394]; positive regulation of MAP kinase activity [GO:0043406]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of Notch signaling pathway [GO:0045747]; positive regulation of ovarian follicle development [GO:2000386]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of platelet-derived growth factor receptor-beta signaling pathway [GO:2000588]; positive regulation of podosome assembly [GO:0071803]; positive regulation of protein autophosphorylation [GO:0031954]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein processing [GO:0010954]; positive regulation of protein serine/threonine kinase activity [GO:0071902]; positive regulation of protein transport [GO:0051222]; positive regulation of small GTPase mediated signal transduction [GO:0051057]; positive regulation of smooth muscle cell migration [GO:0014911]; positive regulation of transcription, DNA-templated [GO:0045893]; primary ovarian follicle growth [GO:0001545]; progesterone receptor signaling pathway [GO:0050847]; protein autophosphorylation [GO:0046777]; protein destabilization [GO:0031648]; regulation of bone resorption [GO:0045124]; regulation of caveolin-mediated endocytosis [GO:2001286]; regulation of cell-cell adhesion [GO:0022407]; regulation of cell projection assembly [GO:0060491]; regulation of early endosome to late endosome transport [GO:2000641]; regulation of epithelial cell migration [GO:0010632]; regulation of intracellular estrogen receptor signaling pathway [GO:0033146]; regulation of postsynaptic neurotransmitter receptor activity [GO:0098962]; regulation of protein binding [GO:0043393]; regulation of vascular permeability [GO:0043114]; response to acidic pH [GO:0010447]; response to drug [GO:0042493]; response to electrical stimulus [GO:0051602]; response to interleukin-1 [GO:0070555]; response to mechanical stimulus [GO:0009612]; response to mineralocorticoid [GO:0051385]; response to nutrient levels [GO:0031667]; response to virus [GO:0009615]; signal complex assembly [GO:0007172]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; stress fiber assembly [GO:0043149]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell costimulation [GO:0031295]; transcytosis [GO:0045056]; transforming growth factor beta receptor signaling pathway [GO:0007179]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; uterus development [GO:0060065]; vascular endothelial growth factor receptor signaling pathway [GO:0048010]; viral process [GO:0016032] ATPase binding [GO:0051117]; ATP binding [GO:0005524]; BMP receptor binding [GO:0070700]; cadherin binding [GO:0045296]; connexin binding [GO:0071253]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; estrogen receptor binding [GO:0030331]; growth factor receptor binding [GO:0070851]; heme binding [GO:0020037]; insulin receptor binding [GO:0005158]; integrin binding [GO:0005178]; ion channel binding [GO:0044325]; kinase binding [GO:0019900]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; phosphoprotein binding [GO:0051219]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; ubiquitin protein ligase binding [GO:0031625] GO:0001545; GO:0001819; GO:0002102; GO:0002223; GO:0002862; GO:0004672; GO:0004713; GO:0004714; GO:0004715; GO:0005080; GO:0005102; GO:0005158; GO:0005178; GO:0005524; GO:0005654; GO:0005737; GO:0005739; GO:0005743; GO:0005764; GO:0005770; GO:0005829; GO:0005884; GO:0005886; GO:0005901; GO:0005925; GO:0007049; GO:0007155; GO:0007165; GO:0007169; GO:0007172; GO:0007173; GO:0007179; GO:0007186; GO:0007229; GO:0007411; GO:0008022; GO:0008283; GO:0009612; GO:0009615; GO:0010447; GO:0010632; GO:0010634; GO:0010907; GO:0010954; GO:0014068; GO:0014069; GO:0014911; GO:0016004; GO:0016032; GO:0016236; GO:0018105; GO:0018108; GO:0019899; GO:0019900; GO:0020037; GO:0022407; GO:0030054; GO:0030154; GO:0030168; GO:0030331; GO:0030900; GO:0031234; GO:0031295; GO:0031333; GO:0031625; GO:0031648; GO:0031667; GO:0031954; GO:0032148; GO:0032211; GO:0032587; GO:0032869; GO:0033146; GO:0033625; GO:0034332; GO:0034446; GO:0035306; GO:0035556; GO:0035635; GO:0036035; GO:0036120; GO:0038083; GO:0038096; GO:0038128; GO:0042169; GO:0042476; GO:0042493; GO:0043005; GO:0043065; GO:0043066; GO:0043114; GO:0043149; GO:0043154; GO:0043274; GO:0043393; GO:0043406; GO:0043552; GO:0044325; GO:0045056; GO:0045087; GO:0045121; GO:0045124; GO:0045296; GO:0045453; GO:0045737; GO:0045747; GO:0045892; GO:0045893; GO:0046628; GO:0046777; GO:0046875; GO:0048010; GO:0048011; GO:0048013; GO:0048041; GO:0048471; GO:0048477; GO:0050731; GO:0050847; GO:0050900; GO:0051057; GO:0051117; GO:0051219; GO:0051222; GO:0051385; GO:0051602; GO:0051895; GO:0051897; GO:0051902; GO:0051974; GO:0060065; GO:0060444; GO:0060491; GO:0060576; GO:0070062; GO:0070102; GO:0070301; GO:0070374; GO:0070555; GO:0070700; GO:0070851; GO:0071222; GO:0071253; GO:0071375; GO:0071393; GO:0071398; GO:0071456; GO:0071498; GO:0071803; GO:0071902; GO:0086098; GO:0090263; GO:0097110; GO:0098609; GO:0098962; GO:0098978; GO:0099091; GO:1900182; GO:1903997; GO:2000386; GO:2000394; GO:2000573; GO:2000588; GO:2000641; GO:2000811; GO:2001237; GO:2001243; GO:2001286 PF07714;PF00017;PF00018; IPR011009;IPR000719;IPR017441;IPR001245;IPR000980;IPR036860;IPR036028;IPR001452;IPR008266;IPR020635; 0 Q8W4L3 Serine/threonine-protein kinase BSK3 (EC 2.7.11.1) (Brassinosteroid-signaling kinase 3) Arabidopsis thaliana (Mouse-ear cress) GKSQSKLS cytosol [GO:0005829]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506] brassinosteroid mediated signaling pathway [GO:0009742] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0005524; GO:0005829; GO:0005886; GO:0009506; GO:0009742; GO:0106310; GO:0106311 PF07714; IPR011009;IPR000719;IPR001245;IPR011990; 0 Q9FIL1 Serine/threonine-protein kinase BSK5 (EC 2.7.11.1) (Brassinosteroid-signaling kinase 5) Arabidopsis thaliana (Mouse-ear cress) GKAQSKRS plasma membrane [GO:0005886]; plasmodesma [GO:0009506] brassinosteroid mediated signaling pathway [GO:0009742]; response to abscisic acid [GO:0009737]; response to cold [GO:0009409]; response to salt stress [GO:0009651] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0005524; GO:0005886; GO:0009409; GO:0009506; GO:0009651; GO:0009737; GO:0009742; GO:0106310; GO:0106311 PF07714; IPR011009;IPR000719;IPR001245;IPR011990; 0 Q9M324 Serine/threonine-protein kinase BSK6 (EC 2.7.11.1) (Brassinosteroid-signaling kinase 6) Arabidopsis thaliana (Mouse-ear cress) GMAFSKLF plasma membrane [GO:0005886] brassinosteroid mediated signaling pathway [GO:0009742] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0005524; GO:0005886; GO:0009742; GO:0106310; GO:0106311 PF07714; IPR011009;IPR000719;IPR001245;IPR011990; 0 Q9FHD7 Serine/threonine-protein kinase BSK8 (EC 2.7.11.1) (Brassinosteroid-signaling kinase 8) Arabidopsis thaliana (Mouse-ear cress) GKVLSKIF plasma membrane [GO:0005886]; plastid [GO:0009536] brassinosteroid mediated signaling pathway [GO:0009742] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0005524; GO:0005886; GO:0009536; GO:0009742; GO:0106310; GO:0106311 PF07714; IPR011009;IPR000719;IPR001245;IPR011990; 0 P34164 SNF1 protein kinase subunit beta-2 (Protein SPM2) (SNF1-interacting protein 2) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) GSSKSKPK cytoplasm [GO:0005737]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; plasma membrane [GO:0005886] cellular response to glucose starvation [GO:0042149]; invasive growth in response to glucose limitation [GO:0001403]; positive regulation of pseudohyphal growth [GO:2000222]; protein phosphorylation [GO:0006468]; regulation of primary metabolic process [GO:0080090]; regulation of protein-containing complex assembly [GO:0043254]; regulation of protein kinase activity [GO:0045859]; signal transduction [GO:0007165] protein kinase binding [GO:0019901] GO:0001403; GO:0005634; GO:0005737; GO:0005886; GO:0006468; GO:0007165; GO:0019901; GO:0031588; GO:0042149; GO:0043254; GO:0045859; GO:0080090; GO:2000222 PF16561;PF04739; IPR032640;IPR006828;IPR037256;IPR013783;IPR014756;IPR030077; 0 Q9NUM4 Transmembrane protein 106B Homo sapiens (Human) GGKLSKKK endosome [GO:0005768]; integral component of membrane [GO:0016021]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764] dendrite morphogenesis [GO:0048813]; lysosomal transport [GO:0007041]; lysosome localization [GO:0032418]; lysosome organization [GO:0007040] GO:0005764; GO:0005765; GO:0005768; GO:0007040; GO:0007041; GO:0016021; GO:0031902; GO:0032418; GO:0048813 PF07092; IPR009790; 0 P25020 Tyrosine-protein kinase transforming protein Src (EC 2.7.10.2) (pp60v-src) (p60-Src) (v-Src) Rous sarcoma virus (strain H-19) GKQNSKLR ATP binding [GO:0005524]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] GO:0004714; GO:0004715; GO:0005524; GO:0046872 PF07714;PF00017;PF00018; IPR011009;IPR000719;IPR017441;IPR001245;IPR000980;IPR036860;IPR036028;IPR001452;IPR008266;IPR020635; 0 P39968 Vacuolar protein 8 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) GARASVLS cytosol [GO:0005829]; fungal-type vacuole membrane [GO:0000329]; integral component of membrane [GO:0016021]; membrane raft [GO:0045121]; Myo2p-Vac17p-Vac8p transport complex [GO:0071563]; nucleus-vacuole junction [GO:0071561]; phagophore assembly site [GO:0000407] autophagosome assembly [GO:0000045]; autophagy [GO:0006914]; Cvt vesicle assembly [GO:0071255]; macroautophagy [GO:0016236]; nucleus-vacuole junction assembly [GO:0071562]; pexophagy [GO:0000425]; piecemeal microautophagy of the nucleus [GO:0034727]; protein localization to membrane raft [GO:1903044]; ribophagy [GO:0034517]; vacuole fusion, non-autophagic [GO:0042144]; vacuole inheritance [GO:0000011] identical protein binding [GO:0042802]; protein-membrane adaptor activity [GO:0043495] GO:0000011; GO:0000045; GO:0000329; GO:0000407; GO:0000425; GO:0005829; GO:0006914; GO:0016021; GO:0016236; GO:0034517; GO:0034727; GO:0042144; GO:0042802; GO:0043495; GO:0045121; GO:0071255; GO:0071561; GO:0071562; GO:0071563; GO:1903044 PF00514; IPR011989;IPR016024;IPR000225; 1 Q9Y478 5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb) Homo sapiens (Human) GNILTCCV cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634] cell cycle arrest [GO:0007050]; fatty acid biosynthetic process [GO:0006633]; macroautophagy [GO:0016236]; nail development [GO:0035878]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of gene expression [GO:0010628]; protein phosphorylation [GO:0006468]; regulation of catalytic activity [GO:0050790]; regulation of macroautophagy [GO:0016241]; regulation of primary metabolic process [GO:0080090]; regulation of signal transduction by p53 class mediator [GO:1901796]; signal transduction [GO:0007165] protein kinase activity [GO:0004672]; protein kinase binding [GO:0019901] GO:0004672; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0006468; GO:0006633; GO:0007050; GO:0007165; GO:0010628; GO:0016236; GO:0016241; GO:0019901; GO:0031588; GO:0035878; GO:0050790; GO:0080090; GO:0120162; GO:1901796 PF16561;PF04739; IPR032640;IPR039160;IPR006828;IPR037256;IPR013783;IPR014756; 1 Q8WWI5 Choline transporter-like protein 1 (CDw92) (Solute carrier family 44 member 1) (CD antigen CD92) Homo sapiens (Human) GCCSSASS cytosol [GO:0005829]; extracellular exosome [GO:0070062]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] choline transmembrane transporter activity [GO:0015220]; transmembrane transporter activity [GO:0022857] choline catabolic process [GO:0042426]; choline transport [GO:0015871]; phosphatidylcholine biosynthetic process [GO:0006656]; transmembrane transport [GO:0055085]; transport across blood-brain barrier [GO:0150104] GO:0005654; GO:0005739; GO:0005741; GO:0005829; GO:0005886; GO:0006656; GO:0015220; GO:0015871; GO:0016020; GO:0016021; GO:0022857; GO:0042426; GO:0055085; GO:0070062; GO:0150104 PF04515; IPR007603; 1 Q13286 Battenin (Batten disease protein) (Protein CLN3) Homo sapiens (Human) GNTLTCCV autolysosome [GO:0044754]; autophagosome [GO:0005776]; caveola [GO:0005901]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; Golgi stack [GO:0005795]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of membrane [GO:0016021]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; recycling endosome [GO:0055037]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802]; vacuole [GO:0005773] action potential [GO:0001508]; amyloid precursor protein catabolic process [GO:0042987]; arginine transport [GO:0015809]; associative learning [GO:0008306]; autophagosome-lysosome fusion [GO:0061909]; autophagosome maturation [GO:0097352]; cellular water homeostasis [GO:0009992]; glycerophospholipid biosynthetic process [GO:0046474]; glycolipid transport [GO:0046836]; Golgi to lysosome transport [GO:0090160]; ionotropic glutamate receptor signaling pathway [GO:0035235]; learning or memory [GO:0007611]; lysosomal lumen acidification [GO:0007042]; lysosomal lumen pH elevation [GO:0035752]; lysosomal protein catabolic process [GO:1905146]; lysosome organization [GO:0007040]; membrane organization [GO:0061024]; negative regulation of apoptotic process [GO:0043066]; negative regulation of catalytic activity [GO:0043086]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of proteolysis [GO:0045861]; neuromuscular process controlling balance [GO:0050885]; neurotransmitter metabolic process [GO:0042133]; phagosome-lysosome docking [GO:0090384]; phagosome-lysosome fusion [GO:0090385]; plasma membrane raft organization [GO:0044857]; positive regulation of caveolin-mediated endocytosis [GO:2001288]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998]; positive regulation of pinocytosis [GO:0048549]; protein processing [GO:0016485]; receptor-mediated endocytosis [GO:0006898]; regulation of arginine biosynthetic process [GO:1900079]; regulation of autophagosome maturation [GO:1901096]; regulation of cellular response to osmotic stress [GO:0106049]; regulation of cytoskeleton organization [GO:0051493]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of fibroblast migration [GO:0010762]; regulation of intracellular pH [GO:0051453]; regulation of modification of synaptic structure [GO:1905244]; regulation of phagosome maturation [GO:1905162]; regulation of protein localization to plasma membrane [GO:1903076]; regulation of protein processing [GO:0070613]; regulation of short-term neuronal synaptic plasticity [GO:0048172]; regulation of synaptic transmission, GABAergic [GO:0032228]; regulation of synaptic transmission, glutamatergic [GO:0051966]; renal potassium excretion [GO:0036359]; vesicle transport along microtubule [GO:0047496] glycolipid binding [GO:0051861]; sulfatide binding [GO:0120146] GO:0000139; GO:0001508; GO:0005634; GO:0005737; GO:0005764; GO:0005765; GO:0005769; GO:0005770; GO:0005773; GO:0005776; GO:0005783; GO:0005794; GO:0005795; GO:0005802; GO:0005829; GO:0005886; GO:0005901; GO:0006898; GO:0007040; GO:0007042; GO:0007611; GO:0008021; GO:0008306; GO:0009992; GO:0010762; GO:0015809; GO:0016021; GO:0016485; GO:0030176; GO:0031901; GO:0031902; GO:0032228; GO:0035235; GO:0035752; GO:0036359; GO:0042133; GO:0042987; GO:0042998; GO:0043005; GO:0043066; GO:0043086; GO:0043524; GO:0044754; GO:0044857; GO:0045121; GO:0045861; GO:0046474; GO:0046836; GO:0047496; GO:0048172; GO:0048549; GO:0050885; GO:0051453; GO:0051480; GO:0051493; GO:0051861; GO:0051966; GO:0055037; GO:0061024; GO:0061909; GO:0070613; GO:0090160; GO:0090384; GO:0090385; GO:0097352; GO:0106049; GO:0120146; GO:1900079; GO:1901096; GO:1903076; GO:1905146; GO:1905162; GO:1905244; GO:2001288 PF02487; IPR003492;IPR018460;IPR036259; 1 Q969F2 Protein naked cuticle homolog 2 (Naked-2) (hNkd2) Homo sapiens (Human) GKLQSKHA basolateral plasma membrane [GO:0016323]; cell periphery [GO:0071944]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; exocytic vesicle [GO:0070382]; lateral plasma membrane [GO:0016328]; plasma membrane [GO:0005886] ATPase binding [GO:0051117]; calcium ion binding [GO:0005509]; growth factor binding [GO:0019838]; myosin heavy chain binding [GO:0032036]; ubiquitin protein ligase binding [GO:0031625] exocytosis [GO:0006887]; Golgi vesicle fusion to target membrane [GO:0048210]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of Wnt signaling pathway [GO:0030178]; positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; positive regulation of protein localization to plasma membrane [GO:1903078]; positive regulation of protein processing [GO:0010954]; protein localization to plasma membrane [GO:0072659]; Wnt signaling pathway [GO:0016055] GO:0005509; GO:0005737; GO:0005886; GO:0006887; GO:0010954; GO:0016055; GO:0016323; GO:0016328; GO:0019838; GO:0030178; GO:0031410; GO:0031625; GO:0032036; GO:0032436; GO:0048210; GO:0051117; GO:0070382; GO:0071944; GO:0072659; GO:0090090; GO:1903078 IPR011992;IPR002048;IPR040140; 1 P07948 Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn) Homo sapiens (Human) GCIKSKGK adherens junction [GO:0005912]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; endocytic vesicle membrane [GO:0030666]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glutamatergic synapse [GO:0098978]; Golgi apparatus [GO:0005794]; integrin alpha2-beta1 complex [GO:0034666]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; membrane raft [GO:0045121]; mitochondrial crista [GO:0030061]; mitochondrial intermembrane space [GO:0005758]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic specialization, intracellular component [GO:0099091] ATP binding [GO:0005524]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; gamma-tubulin binding [GO:0043015]; glycosphingolipid binding [GO:0043208]; integrin binding [GO:0005178]; kinase activity [GO:0016301]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphoprotein binding [GO:0051219]; phosphorylation-dependent protein binding [GO:0140031]; platelet-derived growth factor receptor binding [GO:0005161]; protein tyrosine kinase activity [GO:0004713]; scaffold protein binding [GO:0097110]; SH3 domain binding [GO:0017124]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; transmembrane transporter binding [GO:0044325]; ubiquitin protein ligase binding [GO:0031625] adaptive immune response [GO:0002250]; B cell homeostasis [GO:0001782]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to extracellular stimulus [GO:0031668]; cellular response to heat [GO:0034605]; cellular response to retinoic acid [GO:0071300]; dendritic cell differentiation [GO:0097028]; ephrin receptor signaling pathway [GO:0048013]; erythrocyte differentiation [GO:0030218]; Fc-epsilon receptor signaling pathway [GO:0038095]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; Fc receptor mediated inhibitory signaling pathway [GO:0002774]; Fc receptor mediated stimulatory signaling pathway [GO:0002431]; growth hormone receptor signaling pathway via JAK-STAT [GO:0060397]; histamine secretion by mast cell [GO:0002553]; immune response-regulating cell surface receptor signaling pathway [GO:0002768]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; negative regulation of B cell proliferation [GO:0030889]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of immune response [GO:0050777]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of intracellular signal transduction [GO:1902532]; negative regulation of MAP kinase activity [GO:0043407]; negative regulation of mast cell proliferation [GO:0070667]; negative regulation of myeloid leukocyte differentiation [GO:0002762]; negative regulation of protein phosphorylation [GO:0001933]; negative regulation of toll-like receptor 2 signaling pathway [GO:0034136]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; neuron projection development [GO:0031175]; oligodendrocyte development [GO:0014003]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet degranulation [GO:0002576]; positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process [GO:1902961]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of cellular component movement [GO:0051272]; positive regulation of dendritic cell apoptotic process [GO:2000670]; positive regulation of Fc receptor mediated stimulatory signaling pathway [GO:0060369]; positive regulation of glial cell proliferation [GO:0060252]; positive regulation of mast cell proliferation [GO:0070668]; positive regulation of neuron projection development [GO:0010976]; positive regulation of oligodendrocyte progenitor proliferation [GO:0070447]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of stress-activated protein kinase signaling cascade [GO:0070304]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of B cell apoptotic process [GO:0002902]; regulation of B cell receptor signaling pathway [GO:0050855]; regulation of cell adhesion mediated by integrin [GO:0033628]; regulation of cytokine production [GO:0001817]; regulation of ERK1 and ERK2 cascade [GO:0070372]; regulation of erythrocyte differentiation [GO:0045646]; regulation of mast cell activation [GO:0033003]; regulation of mast cell degranulation [GO:0043304]; regulation of monocyte chemotaxis [GO:0090025]; regulation of platelet aggregation [GO:0090330]; regulation of protein phosphorylation [GO:0001932]; regulation of release of sequestered calcium ion into cytosol [GO:0051279]; response to amino acid [GO:0043200]; response to axon injury [GO:0048678]; response to carbohydrate [GO:0009743]; response to drug [GO:0042493]; response to hormone [GO:0009725]; response to insulin [GO:0032868]; response to organic cyclic compound [GO:0014070]; response to sterol depletion [GO:0006991]; response to toxic substance [GO:0009636]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; tolerance induction to self antigen [GO:0002513]; toll-like receptor 4 signaling pathway [GO:0034142]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] GO:0001782; GO:0001817; GO:0001932; GO:0001933; GO:0001934; GO:0002223; GO:0002250; GO:0002431; GO:0002513; GO:0002553; GO:0002576; GO:0002762; GO:0002768; GO:0002774; GO:0002862; GO:0002902; GO:0004713; GO:0004714; GO:0004715; GO:0005102; GO:0005161; GO:0005178; GO:0005524; GO:0005634; GO:0005737; GO:0005758; GO:0005765; GO:0005794; GO:0005829; GO:0005886; GO:0005912; GO:0006468; GO:0006974; GO:0006991; GO:0007165; GO:0007169; GO:0008284; GO:0008285; GO:0009636; GO:0009725; GO:0009743; GO:0010976; GO:0014003; GO:0014069; GO:0014070; GO:0016301; GO:0017124; GO:0018108; GO:0019899; GO:0030061; GO:0030154; GO:0030218; GO:0030335; GO:0030666; GO:0030889; GO:0031175; GO:0031234; GO:0031295; GO:0031625; GO:0031663; GO:0031668; GO:0032868; GO:0033003; GO:0033628; GO:0034136; GO:0034142; GO:0034144; GO:0034605; GO:0034666; GO:0035556; GO:0038095; GO:0038096; GO:0042493; GO:0042531; GO:0043015; GO:0043200; GO:0043208; GO:0043231; GO:0043304; GO:0043407; GO:0043552; GO:0044325; GO:0045087; GO:0045121; GO:0045646; GO:0046777; GO:0046875; GO:0048013; GO:0048471; GO:0048678; GO:0050777; GO:0050853; GO:0050855; GO:0050900; GO:0051219; GO:0051272; GO:0051279; GO:0060252; GO:0060369; GO:0060397; GO:0070062; GO:0070304; GO:0070372; GO:0070373; GO:0070447; GO:0070667; GO:0070668; GO:0071300; GO:0090025; GO:0090330; GO:0097028; GO:0097110; GO:0098978; GO:0099091; GO:0140031; GO:1902532; GO:1902961; GO:2000670 PF07714;PF00017;PF00018; IPR011009;IPR035852;IPR035748;IPR000719;IPR017441;IPR001245;IPR000980;IPR036860;IPR036028;IPR001452;IPR008266;IPR020635; 1 Q5T2Q4 Cyclin-Y-like protein 2 Homo sapiens (Human) GGCAGSRR cytoplasm [GO:0005737]; plasma membrane [GO:0005886] positive regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0045737] cyclin-dependent protein serine/threonine kinase regulator activity [GO:0016538]; protein kinase binding [GO:0019901] GO:0005737; GO:0005886; GO:0016538; GO:0019901; GO:0045737 PF08613; IPR013763;IPR036915;IPR013922;IPR012399; 1 Q66282 Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Capsid protein VP1 (P1D) (Virion protein 1); P2; Protease 2A (P2A) (EC 3.4.22.29) (Picornain 2A) (Protein 2A); Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); P3; Protein 3AB; Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD (EC 3.4.22.28); Protease 3C (EC 3.4.22.28) (Picornain 3C) (P3C); RNA-directed RNA polymerase (RdRp) (EC 2.7.7.48) (3D polymerase) (3Dpol) (Protein 3D) (3D)] Coxsackievirus B3 (strain Woodruff) GAAASRRR host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618] DNA replication [GO:0006260]; endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host gene expression [GO:0039657]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host MDA-5 activity [GO:0039554]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion attachment to host cell [GO:0019062] ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198] GO:0003723; GO:0003724; GO:0003968; GO:0004197; GO:0005198; GO:0005216; GO:0005524; GO:0006260; GO:0006351; GO:0016020; GO:0017111; GO:0018144; GO:0019062; GO:0039520; GO:0039522; GO:0039540; GO:0039545; GO:0039554; GO:0039611; GO:0039618; GO:0039657; GO:0039690; GO:0039694; GO:0039707; GO:0042025; GO:0044162; GO:0044385; GO:0044694; GO:0046872; GO:0051259; GO:0075509 PF08727;PF00548;PF02226;PF00947;PF01552;PF00680;PF00073;PF00910; IPR003593;IPR043502;IPR000605;IPR014759;IPR027417;IPR014838;IPR036203;IPR044067;IPR000081;IPR000199;IPR009003;IPR043504;IPR003138;IPR036988;IPR002527;IPR001676;IPR043128;IPR033703;IPR001205;IPR007094;IPR029053; 1 P03300 Genome polyprotein [Cleaved into: P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Capsid protein VP1 (P1D) (Virion protein 1); P2; Protease 2A (P2A) (EC 3.4.22.29) (Picornain 2A) (Protein 2A); Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); P3; Protein 3AB; Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD (EC 3.4.22.28); Protease 3C (EC 3.4.22.28) (Picornain 3C) (P3C); RNA-directed RNA polymerase (RdRp) (EC 2.7.7.48) (3D polymerase) (3Dpol) (Protein 3D) (3D)] Poliovirus type 1 (strain Mahoney) GNTTSCCV host cell cytoplasmic vesicle membrane [GO:0044162]; host cell nucleus [GO:0042025]; integral to membrane of host cell [GO:0044385]; membrane [GO:0016020]; T=pseudo3 icosahedral viral capsid [GO:0039618]; viral capsid [GO:0019028] endocytosis involved in viral entry into host cell [GO:0075509]; induction by virus of host autophagy [GO:0039520]; pore formation by virus in membrane of host cell [GO:0039707]; pore-mediated entry of viral genome into host cell [GO:0044694]; positive stranded viral RNA replication [GO:0039690]; protein complex oligomerization [GO:0051259]; RNA-protein covalent cross-linking [GO:0018144]; suppression by virus of host MAVS activity [GO:0039545]; suppression by virus of host MDA-5 activity [GO:0039554]; suppression by virus of host mRNA export from nucleus [GO:0039522]; suppression by virus of host RIG-I activity [GO:0039540]; suppression by virus of host translation initiation factor activity [GO:0039611]; transcription, DNA-templated [GO:0006351]; viral RNA genome replication [GO:0039694]; virion assembly [GO:0019068]; virion attachment to host cell [GO:0019062] ATP binding [GO:0005524]; cysteine-type endopeptidase activity [GO:0004197]; ion channel activity [GO:0005216]; metal ion binding [GO:0046872]; nucleoside-triphosphatase activity [GO:0017111]; RNA binding [GO:0003723]; RNA-directed 5'-3' RNA polymerase activity [GO:0003968]; RNA helicase activity [GO:0003724]; structural molecule activity [GO:0005198] GO:0003723; GO:0003724; GO:0003968; GO:0004197; GO:0005198; GO:0005216; GO:0005524; GO:0006351; GO:0016020; GO:0017111; GO:0018144; GO:0019028; GO:0019062; GO:0019068; GO:0039520; GO:0039522; GO:0039540; GO:0039545; GO:0039554; GO:0039611; GO:0039618; GO:0039690; GO:0039694; GO:0039707; GO:0042025; GO:0044162; GO:0044385; GO:0044694; GO:0046872; GO:0051259; GO:0075509 PF08727;PF00548;PF02226;PF00947;PF01552;PF00680;PF00073;PF00910; IPR043502;IPR000605;IPR014759;IPR027417;IPR014838;IPR036203;IPR044067;IPR000081;IPR000199;IPR009003;IPR043504;IPR003138;IPR002527;IPR001676;IPR043128;IPR033703;IPR001205;IPR007094;IPR029053; 1 Q9CRB9 MICOS complex subunit Mic19 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 3) Mus musculus (Mouse) GTAATIQT MICOS complex [GO:0061617]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleus [GO:0005634] cristae formation [GO:0042407]; inner mitochondrial membrane organization [GO:0007007]; mitochondrial fusion [GO:0008053] molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902] GO:0005634; GO:0005739; GO:0005743; GO:0007007; GO:0008053; GO:0019902; GO:0042407; GO:0060090; GO:0061617 1 Q9NX63 MICOS complex subunit MIC19 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 3) Homo sapiens (Human) GTTASTAQ extracellular exosome [GO:0070062]; MIB complex [GO:0140275]; MICOS complex [GO:0061617]; mitochondrial inner membrane [GO:0005743]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; SAM complex [GO:0001401] cristae formation [GO:0042407]; inner mitochondrial membrane organization [GO:0007007]; mitochondrial fusion [GO:0008053] molecular adaptor activity [GO:0060090]; phosphatase binding [GO:0019902] GO:0001401; GO:0005634; GO:0005739; GO:0005743; GO:0007007; GO:0008053; GO:0019902; GO:0042407; GO:0060090; GO:0061617; GO:0070062; GO:0140275 1 P03093 Minor capsid protein VP2 (Minor structural protein VP2) Simian virus 40 (SV40) GGTASTRR host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral capsid [GO:0019028] permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259]; viral entry via permeabilization of inner membrane [GO:0099008]; viral penetration into host nucleus [GO:0075732]; virion attachment to host cell [GO:0019062] DNA binding [GO:0003677]; ion channel activity [GO:0005216]; structural molecule activity [GO:0005198] GO:0003677; GO:0005198; GO:0005216; GO:0016021; GO:0019028; GO:0019062; GO:0039665; GO:0039707; GO:0042025; GO:0044167; GO:0044385; GO:0051259; GO:0075732; GO:0099008 PF00761; IPR001070; 1 P03096 Minor capsid protein VP2 (Minor structural protein VP2) Murine polyomavirus (strain A2) (MPyV) GGTTSTRR host cell endoplasmic reticulum membrane [GO:0044167]; host cell nucleus [GO:0042025]; integral component of membrane [GO:0016021]; viral capsid [GO:0019028] viral entry into host cell [GO:0046718]; viral penetration into host nucleus [GO:0075732] DNA binding [GO:0003677]; structural molecule activity [GO:0005198] GO:0003677; GO:0005198; GO:0016021; GO:0019028; GO:0042025; GO:0044167; GO:0046718; GO:0075732 PF00761; IPR001070; 1 P00387 NADH-cytochrome b5 reductase 3 (B5R) (Cytochrome b5 reductase) (EC 1.6.2.2) (Diaphorase-1) [Cleaved into: NADH-cytochrome b5 reductase 3 membrane-bound form; NADH-cytochrome b5 reductase 3 soluble form] Homo sapiens (Human) GAQLSTLG azurophil granule lumen [GO:0035578]; cytoplasm [GO:0005737]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; extracellular region [GO:0005576]; hemoglobin complex [GO:0005833]; lipid droplet [GO:0005811]; membrane [GO:0016020]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nitric-oxide synthase complex [GO:1903958] blood circulation [GO:0008015]; cholesterol biosynthetic process [GO:0006695]; L-ascorbic acid metabolic process [GO:0019852]; neutrophil degranulation [GO:0043312]; nitric oxide biosynthetic process [GO:0006809]; xenobiotic metabolic process [GO:0006805] ADP binding [GO:0043531]; AMP binding [GO:0016208]; cytochrome-b5 reductase activity, acting on NAD(P)H [GO:0004128]; FAD binding [GO:0071949]; NAD binding [GO:0051287] GO:0004128; GO:0005576; GO:0005737; GO:0005739; GO:0005741; GO:0005783; GO:0005789; GO:0005811; GO:0005833; GO:0006695; GO:0006805; GO:0006809; GO:0008015; GO:0016020; GO:0016208; GO:0019852; GO:0035578; GO:0043312; GO:0043531; GO:0051287; GO:0071949; GO:1903958 PF00970;PF00175; IPR001834;IPR008333;IPR017927;IPR001709;IPR039261;IPR001433;IPR017938; 1 Q9EPI6 NMDA receptor synaptonuclear signaling and neuronal migration factor (Juxtasynaptic attractor of caldendrin on dendritic boutons protein) (Jacob protein) (Nasal embryonic luteinizing hormone-releasing hormone factor) (Nasal embryonic LHRH factor) Rattus norvegicus (Rat) GAAVTLNR apical dendrite [GO:0097440]; cortical cytoskeleton [GO:0030863]; cytoplasm [GO:0005737]; dendrite [GO:0030425]; dendritic spine [GO:0043197]; euchromatin [GO:0000791]; glutamatergic synapse [GO:0098978]; membrane [GO:0016020]; neuron projection [GO:0043005]; nuclear envelope [GO:0005635]; nuclear matrix [GO:0016363]; nuclear membrane [GO:0031965]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886]; postsynapse [GO:0098794]; postsynaptic density [GO:0014069]; synapse [GO:0045202] cellular response to amino acid stimulus [GO:0071230]; cellular response to electrical stimulus [GO:0071257]; cellular response to gonadotropin stimulus [GO:0071371]; positive regulation of neuron migration [GO:2001224]; positive regulation of protein dephosphorylation [GO:0035307]; postsynapse to nucleus signaling pathway [GO:0099527]; regulation of dendrite morphogenesis [GO:0048814]; regulation of neuronal synaptic plasticity [GO:0048168]; regulation of neuron apoptotic process [GO:0043523] calcium-dependent protein binding [GO:0048306] GO:0000791; GO:0005634; GO:0005635; GO:0005737; GO:0005886; GO:0014069; GO:0016020; GO:0016363; GO:0030425; GO:0030863; GO:0031965; GO:0035307; GO:0043005; GO:0043197; GO:0043204; GO:0043523; GO:0045202; GO:0048168; GO:0048306; GO:0048814; GO:0071230; GO:0071257; GO:0071371; GO:0097440; GO:0098794; GO:0098978; GO:0099527; GO:2001224 IPR033374; 1 Q9ULE6 Paladin Homo sapiens (Human) GAQLSLVV cytoplasm [GO:0005737]; cytosol [GO:0005829] protein tyrosine phosphatase activity [GO:0004725] GO:0004725; GO:0005737; GO:0005829 IPR029021;IPR003595; 1 P68446 Protein E7 Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) GAQVSTQK host cell cytoplasm [GO:0030430] GO:0030430 PF17467; IPR035345; 1 P07612 Protein L1 (Virion membrane protein M25) Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) GAALTLLG integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036] viral entry into host cell [GO:0046718]; virion attachment to host cell [GO:0019062] GO:0016021; GO:0019031; GO:0019062; GO:0046718; GO:0055036 PF02442; IPR003472; 1 P22219 Serine/threonine-protein kinase VPS15 (EC 2.7.11.1) (Golgi-retention defective mutant protein 8) (Vacuolar protein sorting-associated protein 15) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) GAALTILV endosome membrane [GO:0010008]; fungal-type vacuole membrane [GO:0000329]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; mitochondrion [GO:0005739]; nucleus-vacuole junction [GO:0071561]; phosphatidylinositol 3-kinase complex, class III, type I [GO:0034271]; phosphatidylinositol 3-kinase complex, class III, type II [GO:0034272]; vacuole-isolation membrane contact site [GO:0120095] autophagy of peroxisome [GO:0030242]; inositol lipid-mediated signaling [GO:0048017]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; positive regulation of transcription elongation from RNA polymerase II promoter [GO:0032968]; protein phosphorylation [GO:0006468]; protein retention in Golgi apparatus [GO:0045053]; protein targeting to vacuole [GO:0006623]; vacuole inheritance [GO:0000011] ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311]; ubiquitin binding [GO:0043130] GO:0000011; GO:0000329; GO:0004674; GO:0005524; GO:0005739; GO:0005770; GO:0005794; GO:0006468; GO:0006623; GO:0010008; GO:0016236; GO:0030242; GO:0032968; GO:0034271; GO:0034272; GO:0043130; GO:0045053; GO:0045324; GO:0048017; GO:0071561; GO:0106310; GO:0106311; GO:0120095 PF00069; IPR011989;IPR016024;IPR021133;IPR011009;IPR000719;IPR008271;IPR015943;IPR001680;IPR017986;IPR036322; 1 P16710 Virion membrane protein A16 Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) GAQVSSQK integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036] membrane fusion involved in viral entry into host cell [GO:0039663] GO:0016021; GO:0019031; GO:0039663; GO:0055036 PF03003; IPR004251; 2 O81445 Calcineurin B-like protein 1 (SOS3-like calcium-binding protein 5) Arabidopsis thaliana (Mouse-ear cress) GLCASSEK cytoplasm [GO:0005737]; cytosol [GO:0005829]; plasma membrane [GO:0005886]; pollen tube [GO:0090406] abscisic acid-activated signaling pathway [GO:0009738]; calcium-mediated signaling [GO:0019722]; pollen tube growth [GO:0009860]; response to cold [GO:0009409]; response to osmotic stress [GO:0006970]; response to salt stress [GO:0009651]; response to water deprivation [GO:0009414] calcium ion binding [GO:0005509]; kinase binding [GO:0019900] GO:0005509; GO:0005737; GO:0005829; GO:0005886; GO:0006970; GO:0009409; GO:0009414; GO:0009651; GO:0009738; GO:0009860; GO:0019722; GO:0019900; GO:0090406 PF13499; IPR011992;IPR018247;IPR002048; 2 Q9LTB8 Calcineurin B-like protein 9 Arabidopsis thaliana (Mouse-ear cress) GSQSSKAP cytoplasm [GO:0005737]; plasma membrane [GO:0005886]; plastid [GO:0009536] abscisic acid-activated signaling pathway [GO:0009738]; pollen tube growth [GO:0009860]; response to water deprivation [GO:0009414] calcium ion binding [GO:0005509]; kinase binding [GO:0019900] GO:0005509; GO:0005737; GO:0005886; GO:0009414; GO:0009536; GO:0009738; GO:0009860; GO:0019900 PF13202; IPR011992;IPR018247;IPR002048; 2 Q7XJR9 Calcium-dependent protein kinase 16 (EC 2.7.11.1) Arabidopsis thaliana (Mouse-ear cress) GCIKSKEN cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886] intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777] ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0004672; GO:0004683; GO:0005509; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0009931; GO:0018105; GO:0035556; GO:0046777; GO:0106310; GO:0106311 PF13499;PF00069; IPR011992;IPR018247;IPR002048;IPR011009;IPR000719;IPR017441;IPR008271; 2 Q0D715 Calcium-dependent protein kinase 18 (OsCDPK18) (OsCPK18) (EC 2.7.11.1) (OsCDPK5) Oryza sativa subsp. japonica (Rice) GCCQSSFL cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886] defense response to fungus [GO:0050832]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777] ATP binding [GO:0005524]; calcium-dependent protein kinase activity [GO:0010857]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0004683; GO:0005509; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0009931; GO:0010857; GO:0018105; GO:0035556; GO:0046777; GO:0050832; GO:0106310; GO:0106311 PF13499;PF00069; IPR011992;IPR018247;IPR002048;IPR011009;IPR000719;IPR017441;IPR008271; 2 P04289 Cytoplasmic envelopment protein 3 Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) GASGSKAR host cell Golgi membrane [GO:0044178]; host cell plasma membrane [GO:0020002]; viral tegument [GO:0019033]; virion membrane [GO:0055036] anatomical structure morphogenesis [GO:0009653]; viral budding from Golgi membrane [GO:0046760] GO:0009653; GO:0019033; GO:0020002; GO:0044178; GO:0046760; GO:0055036 PF11094; IPR024351;IPR016395; 2 P11283 Gag-Pro-Pol polyprotein [Cleaved into: Matrix protein p10; Phosphorylated protein pp21; Protein p3; Protein p8; Protein n; Capsid protein p27; Nucleocapsid protein-dUTPase (NC-dUTPase) (EC 3.6.1.23); Protease (EC 3.4.23.-); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)] Mouse mammary tumor virus (strain C3H) (MMTV) GAQFSKTA viral nucleocapsid [GO:0019013] DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826] aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; dUTP diphosphatase activity [GO:0004170]; nucleotide binding [GO:0000166]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270] GO:0000166; GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004170; GO:0004190; GO:0004523; GO:0006310; GO:0008270; GO:0015074; GO:0019013; GO:0039660; GO:0044826; GO:0046718; GO:0075713 PF00692;PF02337;PF00607;PF00552;PF02022;PF00075;PF00665;PF00077;PF00078;PF06817;PF00098; IPR001969;IPR003322;IPR038124;IPR043502;IPR029054;IPR036157;IPR033704;IPR000721;IPR017856;IPR036862;IPR001037;IPR001584;IPR003308;IPR001995;IPR021109;IPR034170;IPR018061;IPR008916;IPR008919;IPR010999;IPR043128;IPR012337;IPR002156;IPR036397;IPR000477;IPR010661;IPR001878;IPR036875; 2 P16051 Guanine nucleotide-binding protein alpha-2 subunit (G alpha-2) Dictyostelium discoideum (Slime mold) GICASSME cytosol [GO:0005829]; heterotrimeric G-protein complex [GO:0005834]; plasma membrane [GO:0005886] actin filament polymerization [GO:0030041]; activation of GTPase activity [GO:0090630]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; aggregation involved in sorocarp development [GO:0031152]; chemotaxis [GO:0006935]; phagocytosis [GO:0006909]; positive regulation of guanylate cyclase activity [GO:0031284]; positive regulation of guanyl-nucleotide exchange factor activity [GO:1905099]; positive regulation of phospholipase C activity [GO:0010863]; regulation of Ras protein signal transduction [GO:0046578] G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872] GO:0001664; GO:0003924; GO:0005525; GO:0005829; GO:0005834; GO:0005886; GO:0006909; GO:0006935; GO:0007188; GO:0007189; GO:0010863; GO:0030041; GO:0031152; GO:0031284; GO:0031683; GO:0046578; GO:0046872; GO:0090630; GO:1905099 PF00503; IPR002975;IPR001019;IPR011025;IPR027417; 2 P10823 Guanine nucleotide-binding protein alpha-2 subunit (GP2-alpha) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) GCLHSKTA cytosol [GO:0005829]; heterotrimeric G-protein complex [GO:0005834]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; ascospore formation [GO:0030437]; glucose mediated signaling pathway [GO:0010255]; hexose mediated signaling [GO:0009757]; invasive growth in response to glucose limitation [GO:0001403]; protein kinase A signaling [GO:0010737]; pseudohyphal growth [GO:0007124]; regulation of cell size [GO:0008361]; signal transduction [GO:0007165] G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872] GO:0001403; GO:0001664; GO:0003924; GO:0005525; GO:0005739; GO:0005829; GO:0005834; GO:0005886; GO:0007124; GO:0007165; GO:0007188; GO:0007189; GO:0008361; GO:0009757; GO:0010255; GO:0010737; GO:0030437; GO:0031683; GO:0046872 PF00503; IPR002975;IPR001019;IPR011025;IPR027417; 2 O95843 Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C) Homo sapiens (Human) GCCQSLFS photoreceptor disc membrane [GO:0097381] regulation of rhodopsin mediated signaling pathway [GO:0022400]; signal transduction [GO:0007165]; visual perception [GO:0007601] calcium ion binding [GO:0005509]; calcium sensitive guanylate cyclase activator activity [GO:0008048] GO:0005509; GO:0007165; GO:0007601; GO:0008048; GO:0022400; GO:0097381 PF13202;PF13499; IPR011992;IPR018247;IPR002048;IPR032992;IPR028846; 2 Q9NS86 LanC-like protein 2 (Testis-specific adriamycin sensitivity protein) Homo sapiens (Human) GLCSSSSA cortical actin cytoskeleton [GO:0030864]; cytosol [GO:0005829]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] carbohydrate metabolic process [GO:0005975]; negative regulation of transcription, DNA-templated [GO:0045892]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789] ATP binding [GO:0005524]; GTP binding [GO:0005525]; phosphatidylinositol-3-phosphate binding [GO:0032266]; phosphatidylinositol-4-phosphate binding [GO:0070273]; phosphatidylinositol-5-phosphate binding [GO:0010314] GO:0005524; GO:0005525; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0005975; GO:0009789; GO:0010314; GO:0030864; GO:0032266; GO:0045892; GO:0070273 PF05147; IPR012341;IPR007822;IPR020464; 2 P49006 MARCKS-related protein (MARCKS-like protein 1) (Macrophage myristoylated alanine-rich C kinase substrate) (Mac-MARCKS) (MacMARCKS) Homo sapiens (Human) GCFHSKAA cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; extracellular exosome [GO:0070062]; plasma membrane [GO:0005886] actin filament organization [GO:0007015]; central nervous system development [GO:0007417]; positive regulation of cell population proliferation [GO:0008284] actin filament binding [GO:0051015]; calmodulin binding [GO:0005516] GO:0005516; GO:0005737; GO:0005856; GO:0005886; GO:0007015; GO:0007417; GO:0008284; GO:0051015; GO:0070062 PF02063; IPR002101; 2 P84085 ADP-ribosylation factor 5 Homo sapiens (Human) GLTVSALF extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] GTPase activity [GO:0003924]; GTP binding [GO:0005525] intracellular protein transport [GO:0006886]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192] GO:0003924; GO:0005525; GO:0005794; GO:0005886; GO:0006886; GO:0006890; GO:0016192; GO:0048471; GO:0070062 PF00025; IPR027417;IPR005225;IPR006689; 2 Q5VT66 Mitochondrial amidoxime-reducing component 1 (mARC1) (EC 1.7.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 1) (MOSC domain-containing protein 1) (Moco sulfurase C-terminal domain-containing protein 1) Homo sapiens (Human) GETMSKRL integral component of membrane [GO:0016021]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nitric-oxide synthase complex [GO:1903958] cellular detoxification of nitrogen compound [GO:0070458]; detoxification of nitrogen compound [GO:0051410]; nitrate metabolic process [GO:0042126]; nitric oxide biosynthetic process [GO:0006809]; xenobiotic metabolic process [GO:0006805] molybdenum ion binding [GO:0030151]; molybdopterin cofactor binding [GO:0043546]; nitrate reductase activity [GO:0008940]; nitrite reductase activity [GO:0098809]; oxidoreductase activity, acting on other nitrogenous compounds as donors [GO:0016661]; pyridoxal phosphate binding [GO:0030170] GO:0005739; GO:0005741; GO:0006805; GO:0006809; GO:0008940; GO:0016021; GO:0016661; GO:0030151; GO:0030170; GO:0042126; GO:0043546; GO:0051410; GO:0070458; GO:0098809; GO:1903958 PF03473;PF03476; IPR005302;IPR005303;IPR011037; 2 P29966 Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (80K-L protein) (PKCSL) Homo sapiens (Human) GVSGSKGQ actin cytoskeleton [GO:0015629]; actin filament bundle [GO:0032432]; cell cortex [GO:0005938]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; germinal vesicle [GO:0042585]; plasma membrane [GO:0005886] actin crosslink formation [GO:0051764]; actin filament bundle assembly [GO:0051017]; actin filament organization [GO:0007015]; central nervous system development [GO:0007417] actin filament binding [GO:0051015]; calmodulin binding [GO:0005516]; identical protein binding [GO:0042802]; protein kinase C binding [GO:0005080] GO:0005080; GO:0005516; GO:0005737; GO:0005813; GO:0005886; GO:0005925; GO:0005938; GO:0007015; GO:0007417; GO:0015629; GO:0032432; GO:0042585; GO:0042802; GO:0051015; GO:0051017; GO:0051764; GO:0070062 PF02063; IPR002101; 2 Q9UPV7 PHD finger protein 24 Homo sapiens (Human) GAAGSSAL detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; gamma-aminobutyric acid signaling pathway [GO:0007214]; regulation of G protein-coupled receptor signaling pathway [GO:0008277]; regulation of synaptic transmission, GABAergic [GO:0032228] metal ion binding [GO:0046872] GO:0007214; GO:0008277; GO:0032228; GO:0046872; GO:0050966 PF16744; IPR011992;IPR031946;IPR019786;IPR011011;IPR013083; 2 Q84ME1 Probable E3 ubiquitin-protein ligase LUL3 (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase LUL3) (Protein LOG2-LIKE UBIQUITIN LIGASE 3) (RING finger protein 398) Arabidopsis thaliana (Mouse-ear cress) GLCGSKTQ protein ubiquitination [GO:0016567] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] GO:0004842; GO:0016567; GO:0046872; GO:0061630 IPR001841;IPR013083; 2 Q9LYB4 Probable glutathione peroxidase 5 (EC 1.11.1.9) Arabidopsis thaliana (Mouse-ear cress) GISLSKRR cytosol [GO:0005829]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; plasma membrane [GO:0005886] embryo development ending in seed dormancy [GO:0009793]; response to oxidative stress [GO:0006979] glutathione peroxidase activity [GO:0004602]; peroxidase activity [GO:0004601] GO:0004601; GO:0004602; GO:0005783; GO:0005829; GO:0005886; GO:0006979; GO:0009793; GO:0012505 PF00255; IPR000889;IPR029759;IPR029760;IPR036249; 2 Q7XJT7 Probable inactive receptor-like kinase BSK12 (Brassinosteroid-signaling kinase 12) (Protein SHORT SUSPENSOR) Arabidopsis thaliana (Mouse-ear cress) GCFHSTAA cytoplasmic side of plasma membrane [GO:0009898] brassinosteroid mediated signaling pathway [GO:0009742]; positive regulation of intracellular signal transduction [GO:1902533]; suspensor development [GO:0010098]; zygote elongation [GO:0080159] ATP binding [GO:0005524]; protein serine/threonine kinase activity [GO:0004674] GO:0004674; GO:0005524; GO:0009742; GO:0009898; GO:0010098; GO:0080159; GO:1902533 PF07714; IPR011009;IPR000719;IPR001245;IPR011990; 2 O75695 Protein XRP2 Homo sapiens (Human) GCCYSLSS centriole [GO:0005814]; ciliary basal body [GO:0036064]; cilium [GO:0005929]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; nuclear body [GO:0016604]; nucleoplasm [GO:0005654]; periciliary membrane compartment [GO:1990075]; plasma membrane [GO:0005886] cell morphogenesis [GO:0000902]; cilium assembly [GO:0060271]; post-Golgi vesicle-mediated transport [GO:0006892]; protein folding [GO:0006457]; protein transport [GO:0015031]; visual perception [GO:0007601] GTPase activator activity [GO:0005096]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; unfolded protein binding [GO:0051082] GO:0000287; GO:0000902; GO:0005096; GO:0005525; GO:0005654; GO:0005737; GO:0005794; GO:0005814; GO:0005886; GO:0005929; GO:0006457; GO:0006892; GO:0007601; GO:0015031; GO:0016604; GO:0031410; GO:0036064; GO:0051082; GO:0060271; GO:0070062; GO:1990075 PF07986; IPR017901;IPR016098;IPR036223;IPR006599;IPR036850;IPR012945;IPR039093; 2 Q6IAA8 Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho) Homo sapiens (Human) GCCYSSEN azurophil granule membrane [GO:0035577]; extracellular exosome [GO:0070062]; ficolin-1-rich granule membrane [GO:0101003]; late endosome membrane [GO:0031902]; lysosomal membrane [GO:0005765]; lysosome [GO:0005764]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; Ragulator complex [GO:0071986]; specific granule membrane [GO:0035579] cell cycle arrest [GO:0007050]; cellular protein localization [GO:0034613]; cellular response to amino acid starvation [GO:0034198]; cellular response to amino acid stimulus [GO:0071230]; cholesterol homeostasis [GO:0042632]; endosomal transport [GO:0016197]; endosome organization [GO:0007032]; lysosome localization [GO:0032418]; lysosome organization [GO:0007040]; neutrophil degranulation [GO:0043312]; positive regulation of MAPK cascade [GO:0043410]; positive regulation of TOR signaling [GO:0032008]; regulation of catalytic activity [GO:0050790]; regulation of cell growth [GO:0001558]; regulation of cholesterol efflux [GO:0010874]; regulation of cholesterol esterification [GO:0010872]; regulation of cholesterol import [GO:0060620]; regulation of macroautophagy [GO:0016241]; regulation of receptor recycling [GO:0001919] GTPase binding [GO:0051020] GO:0001558; GO:0001919; GO:0005764; GO:0005765; GO:0005886; GO:0007032; GO:0007040; GO:0007050; GO:0010872; GO:0010874; GO:0016197; GO:0016241; GO:0031902; GO:0032008; GO:0032418; GO:0034198; GO:0034613; GO:0035577; GO:0035579; GO:0042632; GO:0043312; GO:0043410; GO:0045121; GO:0050790; GO:0051020; GO:0060620; GO:0070062; GO:0071230; GO:0071986; GO:0101003 PF15454; IPR028209; 2 P21457 Recoverin (p26) Bos taurus (Bovine) GASSSSSV cytosol [GO:0005829]; membrane [GO:0016020]; perikaryon [GO:0043204]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750] phototransduction [GO:0007602]; regulation of calcium ion transport [GO:0051924]; visual perception [GO:0007601] calcium ion binding [GO:0005509] GO:0001750; GO:0001917; GO:0005509; GO:0005829; GO:0007601; GO:0007602; GO:0016020; GO:0043204; GO:0051924 PF13499;PF13833; IPR011992;IPR018247;IPR002048;IPR028846; 2 Q944A7 Serine/threonine-protein kinase BSK1 (EC 2.7.11.1) (Brassinosteroid-signaling kinase 1) Arabidopsis thaliana (Mouse-ear cress) GNGKSIAG plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773] brassinosteroid mediated signaling pathway [GO:0009742]; defense response to bacterium [GO:0042742]; defense response to fungus [GO:0050832]; response to abscisic acid [GO:0009737] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0004672; GO:0005524; GO:0005773; GO:0005886; GO:0009506; GO:0009737; GO:0009742; GO:0042742; GO:0050832; GO:0106310; GO:0106311 PF07714; IPR011009;IPR000719;IPR001245;IPR011990; 2 F4I7Y4 Serine/threonine-protein kinase BSK11 (EC 2.7.11.1) (Brassinosteroid-signaling kinase 11) Arabidopsis thaliana (Mouse-ear cress) GNSKSGAL plasma membrane [GO:0005886] brassinosteroid mediated signaling pathway [GO:0009742] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0005524; GO:0005886; GO:0009742; GO:0106310; GO:0106311 PF07714; IPR011009;IPR000719;IPR001245;IPR011990; 2 Q9LS26 Serine/threonine-protein kinase BSK2 (EC 2.7.11.1) (Brassinosteroid-signaling kinase 2) Arabidopsis thaliana (Mouse-ear cress) GLSFSGAR plasma membrane [GO:0005886] brassinosteroid mediated signaling pathway [GO:0009742] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0005524; GO:0005886; GO:0009742; GO:0106310; GO:0106311 PF00069; IPR011009;IPR000719;IPR011990; 2 Q86XR7 TIR domain-containing adapter molecule 2 (TICAM-2) (Putative NF-kappa-B-activating protein 502) (TRIF-related adapter molecule) (Toll-like receptor adaptor protein 3) (Toll/interleukin-1 receptor domain-containing protein) (MyD88-4) Homo sapiens (Human) GSQHSAAA cell projection [GO:0042995]; COPII-coated ER to Golgi transport vesicle [GO:0030134]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum-Golgi intermediate compartment [GO:0005793]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; late endosome [GO:0005770]; late endosome membrane [GO:0031902]; phagocytic cup [GO:0001891]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667] apoptotic signaling pathway [GO:0097190]; cellular response to lipopolysaccharide [GO:0071222]; endoplasmic reticulum to Golgi vesicle-mediated transport [GO:0006888]; Golgi organization [GO:0007030]; I-kappaB kinase/NF-kappaB signaling [GO:0007249]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; intracellular protein transport [GO:0006886]; MyD88-independent toll-like receptor signaling pathway [GO:0002756]; necroptotic process [GO:0070266]; negative regulation of chemokine (C-C motif) ligand 5 production [GO:0071650]; negative regulation of MyD88-independent toll-like receptor signaling pathway [GO:0034128]; negative regulation of toll-like receptor 4 signaling pathway [GO:0034144]; neutrophil degranulation [GO:0043312]; phagocytosis [GO:0006909]; positive regulation of chemokine (C-C motif) ligand 5 production [GO:0071651]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interleukin-18-mediated signaling pathway [GO:2000494]; positive regulation of toll-like receptor 4 signaling pathway [GO:0034145]; toll-like receptor 4 signaling pathway [GO:0034142]; TRAM-dependent toll-like receptor 4 signaling pathway [GO:0035669]; TRIF-dependent toll-like receptor signaling pathway [GO:0035666] GO:0001891; GO:0002756; GO:0005769; GO:0005770; GO:0005783; GO:0005793; GO:0005794; GO:0005886; GO:0006886; GO:0006888; GO:0006909; GO:0006954; GO:0007030; GO:0007249; GO:0010008; GO:0030134; GO:0030667; GO:0031901; GO:0031902; GO:0034128; GO:0034142; GO:0034144; GO:0034145; GO:0035666; GO:0035669; GO:0042995; GO:0043123; GO:0043312; GO:0045087; GO:0070266; GO:0071222; GO:0071650; GO:0071651; GO:0097190; GO:2000494 PF13676; IPR015720;IPR000157;IPR035897; 2 Q9BVX2 Transmembrane protein 106C (Endoplasmic reticulum membrane protein overexpressed in cancer) Homo sapiens (Human) GLCFSSAA endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021] GO:0005789; GO:0016021 PF07092; IPR009790; 2 O75896 Tumor suppressor candidate 2 (Fusion 1 protein) (Fus-1 protein) (PDGFA-associated protein 2) Homo sapiens (Human) GIGKSKIN mitochondrion [GO:0005739] cell cycle [GO:0007049]; cell maturation [GO:0048469]; inflammatory response [GO:0006954]; natural killer cell differentiation [GO:0001779]; negative regulation of interleukin-17 production [GO:0032700]; neutrophil-mediated killing of gram-negative bacterium [GO:0070945]; phagocytosis [GO:0006909]; positive regulation of interleukin-10 production [GO:0032733]; regulation of mitochondrial membrane potential [GO:0051881]; regulation of reactive oxygen species metabolic process [GO:2000377] GO:0001779; GO:0005739; GO:0006909; GO:0006954; GO:0007049; GO:0032700; GO:0032733; GO:0048469; GO:0051881; GO:0070945; GO:2000377 PF15000; IPR029393; 2 P07947 Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes) Homo sapiens (Human) GCFFSKRR cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; microtubule organizing center [GO:0005815]; plasma membrane [GO:0005886] cell differentiation [GO:0030154]; cellular protein modification process [GO:0006464]; ephrin receptor signaling pathway [GO:0048013]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; innate immune response [GO:0045087]; leukocyte migration [GO:0050900]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; regulation of vascular permeability [GO:0043114]; T cell costimulation [GO:0031295]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] ATP binding [GO:0005524]; enzyme binding [GO:0019899]; ion channel binding [GO:0044325]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] GO:0001784; GO:0002862; GO:0004713; GO:0004714; GO:0004715; GO:0005102; GO:0005524; GO:0005794; GO:0005815; GO:0005829; GO:0005886; GO:0005925; GO:0006464; GO:0007169; GO:0019899; GO:0030154; GO:0031234; GO:0031295; GO:0038096; GO:0043114; GO:0044325; GO:0045087; GO:0048013; GO:0050900; GO:0070062 PF07714;PF00017;PF00018; IPR011009;IPR000719;IPR017441;IPR001245;IPR000980;IPR036860;IPR036028;IPR001452;IPR008266;IPR020635;IPR035751; 2 P53139 Uncharacterized protein YGL108C Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) GASSSSAL cytosol [GO:0005829]; plasma membrane [GO:0005886] GO:0005829; GO:0005886 3 Q9MB58 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (6PF-2-K/Fru-2,6-P2ase) (AtF2KP) (PFK/FBPase) [Includes: 6-phosphofructo-2-kinase (EC 2.7.1.105); Fructose-2,6-bisphosphatase (EC 3.1.3.46)] Arabidopsis thaliana (Mouse-ear cress) GSLSSRGK cytosol [GO:0005829]; plasma membrane [GO:0005886] fructose 2,6-bisphosphate metabolic process [GO:0006003]; fructose 6-phosphate metabolic process [GO:0006002]; fructose metabolic process [GO:0006000]; regulation of carbon utilization [GO:0043609] 6-phosphofructo-2-kinase activity [GO:0003873]; ATP binding [GO:0005524]; fructose-2,6-bisphosphate 2-phosphatase activity [GO:0004331]; starch binding [GO:2001070] GO:0003873; GO:0004331; GO:0005524; GO:0005829; GO:0005886; GO:0006000; GO:0006002; GO:0006003; GO:0043609; GO:2001070 PF01591;PF00300; IPR003094;IPR013079;IPR013784;IPR002044;IPR013078;IPR029033;IPR013783;IPR027417;IPR001345; 3 Q02952 A-kinase anchor protein 12 (AKAP-12) (A-kinase anchor protein 250 kDa) (AKAP 250) (Gravin) (Myasthenia gravis autoantigen) Homo sapiens (Human) GAAHSASE cell cortex [GO:0005938]; cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; Schaffer collateral - CA1 synapse [GO:0098685] adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; cellular response to interleukin-1 [GO:0071347]; cellular response to tumor necrosis factor [GO:0071356]; G protein-coupled receptor signaling pathway [GO:0007186]; hepatic stellate cell activation [GO:0035733]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of vascular permeability [GO:0043116]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of hepatic stellate cell migration [GO:0061870]; positive regulation of nitric-oxide synthase biosynthetic process [GO:0051770]; positive regulation of oligodendrocyte apoptotic process [GO:1900143]; positive regulation of protein kinase A signaling [GO:0010739]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of protein kinase A signaling [GO:0010738]; regulation of protein kinase C signaling [GO:0090036]; response to electrical stimulus [GO:0051602]; response to lipopolysaccharide [GO:0032496] adenylate cyclase binding [GO:0008179]; calmodulin binding [GO:0005516]; protein kinase A binding [GO:0051018] GO:0005516; GO:0005737; GO:0005829; GO:0005856; GO:0005886; GO:0005925; GO:0005938; GO:0007186; GO:0007193; GO:0008179; GO:0010738; GO:0010739; GO:0032496; GO:0032760; GO:0035733; GO:0043025; GO:0043116; GO:0050804; GO:0051018; GO:0051602; GO:0051770; GO:0061870; GO:0070374; GO:0071347; GO:0071356; GO:0090036; GO:0098685; GO:1900143 PF10522;PF03832; IPR028540;IPR001573;IPR018459; 3 Q969J3 BLOC-1-related complex subunit 5 (Loss of heterozygosity 12 chromosomal region 1) (Myristoylated lysosomal protein) (Myrlysin) Homo sapiens (Human) GSGSSRSS BORC complex [GO:0099078]; cytoplasmic side of lysosomal membrane [GO:0098574]; intracellular membrane-bounded organelle [GO:0043231]; intrinsic component of membrane [GO:0031224]; plasma membrane [GO:0005886]; synaptic vesicle membrane [GO:0030672] lysosome localization [GO:0032418]; organelle transport along microtubule [GO:0072384]; positive regulation of anterograde synaptic vesicle transport [GO:1903744] GO:0005886; GO:0030672; GO:0031224; GO:0032418; GO:0043231; GO:0072384; GO:0098574; GO:0099078; GO:1903744 PF10158; IPR018780; 3 Q96BS2 Calcineurin B homologous protein 3 (Tescalcin) (TSC) Homo sapiens (Human) GCTLSAED cytoplasm [GO:0005737]; cytosol [GO:0005829]; lamellipodium [GO:0030027]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; ruffle [GO:0001726]; ruffle membrane [GO:0032587] cellular response to retinoic acid [GO:0071300]; male gonad development [GO:0008584]; megakaryocyte differentiation [GO:0030219]; negative regulation of cell population proliferation [GO:0008285]; positive regulation of gene expression [GO:0010628]; positive regulation of granulocyte differentiation [GO:0030854]; positive regulation of megakaryocyte differentiation [GO:0045654]; positive regulation of sodium:proton antiporter activity [GO:0032417]; positive regulation of transcription, DNA-templated [GO:0045893]; protein localization to plasma membrane [GO:0072659]; protein maturation [GO:0051604]; protein stabilization [GO:0050821]; protein transport [GO:0015031]; regulation of cell adhesion mediated by integrin [GO:0033628] calcium ion binding [GO:0005509]; magnesium ion binding [GO:0000287]; phosphatase inhibitor activity [GO:0019212]; protein homodimerization activity [GO:0042803]; protein kinase inhibitor activity [GO:0004860] GO:0000287; GO:0001726; GO:0004860; GO:0005509; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0008285; GO:0008584; GO:0010628; GO:0015031; GO:0019212; GO:0030027; GO:0030219; GO:0030854; GO:0032417; GO:0032587; GO:0033628; GO:0042803; GO:0045654; GO:0045893; GO:0050821; GO:0051604; GO:0071300; GO:0072659 IPR011992;IPR018247;IPR002048; 3 Q717R9 Cystin-1 (Cilia-associated protein) Homo sapiens (Human) GSGISSES ciliary membrane [GO:0060170]; cilium [GO:0005929]; cytoskeleton [GO:0005856]; cytosol [GO:0005829] cilium assembly [GO:0060271] GO:0005829; GO:0005856; GO:0005929; GO:0060170; GO:0060271 3 Q8R4T1 Cystin-1 (Cilia-associated protein) Mus musculus (Mouse) GGRSSCED axoneme [GO:0005930]; ciliary basal body [GO:0036064]; ciliary membrane [GO:0060170]; cytosol [GO:0005829]; membrane [GO:0016020]; nucleus [GO:0005634] inner ear development [GO:0048839]; kidney development [GO:0001822]; negative regulation of DNA-binding transcription factor activity [GO:0043433]; positive regulation of transcription by RNA polymerase II [GO:0045944] chromatin binding [GO:0003682]; transcription corepressor activity [GO:0003714] GO:0001822; GO:0003682; GO:0003714; GO:0005634; GO:0005829; GO:0005930; GO:0016020; GO:0036064; GO:0043433; GO:0045944; GO:0048839; GO:0060170 3 Q7RTS9 Dymeclin (Dyggve-Melchior-Clausen syndrome protein) Homo sapiens (Human) GSGSSRSG cytoplasm [GO:0005737]; Golgi apparatus [GO:0005794]; membrane [GO:0016020] bone development [GO:0060348]; Golgi organization [GO:0007030] enzyme binding [GO:0019899] GO:0005737; GO:0005794; GO:0007030; GO:0016020; GO:0019899; GO:0060348 IPR019142; 3 O60291 E3 ubiquitin-protein ligase MGRN1 (EC 2.3.2.27) (Mahogunin RING finger protein 1) (RING finger protein 156) (RING-type E3 ubiquitin transferase MGRN1) Homo sapiens (Human) GSLPSRRK cytoplasm [GO:0005737]; cytosol [GO:0005829]; early endosome [GO:0005769]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleus [GO:0005634]; plasma membrane [GO:0005886] endosome to lysosome transport [GO:0008333]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; negative regulation of smoothened signaling pathway [GO:0045879]; protein monoubiquitination [GO:0006513]; protein ubiquitination [GO:0016567] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] GO:0004842; GO:0005634; GO:0005737; GO:0005769; GO:0005783; GO:0005829; GO:0005886; GO:0006513; GO:0008333; GO:0016020; GO:0016567; GO:0043231; GO:0043951; GO:0045744; GO:0045879; GO:0046872; GO:0061630; GO:0070062 IPR001841;IPR013083; 3 Q96EQ8 E3 ubiquitin-protein ligase RNF125 (EC 2.3.2.27) (RING finger protein 125) (T-cell RING activation protein 1) (TRAC-1) Homo sapiens (Human) GSVSSLIS Golgi membrane [GO:0000139]; intracellular membrane-bounded organelle [GO:0043231]; VCP-NPL4-UFD1 AAA ATPase complex [GO:0034098] adaptive immune response [GO:0002250]; cellular response to leukemia inhibitory factor [GO:1990830]; negative regulation of RIG-I signaling pathway [GO:0039536]; negative regulation of type I interferon production [GO:0032480]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] p53 binding [GO:0002039]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] GO:0000139; GO:0000209; GO:0002039; GO:0002250; GO:0006511; GO:0008270; GO:0031624; GO:0032480; GO:0034098; GO:0039536; GO:0043231; GO:0061630; GO:1990830 PF05605;PF18574; IPR008598;IPR034734;IPR001841;IPR013083;IPR017907; 3 Q91DM1 Envelope small membrane protein (Protein E) (Glycoprotein 2a) (Protein GP2a) Equine arteritis virus (strain Bucyrus) (EAV) GSGASAED extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi membrane [GO:0044178]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; virion membrane [GO:0055036] pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259] ion channel activity [GO:0005216] GO:0005216; GO:0005576; GO:0016021; GO:0019031; GO:0039707; GO:0044167; GO:0044178; GO:0044385; GO:0051259; GO:0055036 3 P0C6Y6 Envelope small membrane protein (Protein E) (Glycoprotein 2b) (Protein GP2b) (Gs) Porcine reproductive and respiratory syndrome virus (strain Lelystad) (PRRSV) GCASSLPD extracellular region [GO:0005576]; host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi membrane [GO:0044178]; integral component of membrane [GO:0016021]; integral to membrane of host cell [GO:0044385]; viral envelope [GO:0019031]; virion membrane [GO:0055036] pore formation by virus in membrane of host cell [GO:0039707]; protein complex oligomerization [GO:0051259] ion channel activity [GO:0005216] GO:0005216; GO:0005576; GO:0016021; GO:0019031; GO:0039707; GO:0044167; GO:0044178; GO:0044385; GO:0051259; GO:0055036 PF07069; IPR009775; 3 Q9BRQ8 Ferroptosis suppressor protein 1 (FSP1) (EC 1.6.5.-) (Apoptosis-inducing factor homologous mitochondrion-associated inducer of death) (AMID) (p53-responsive gene 3 protein) Homo sapiens (Human) GSSQSVEI cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular space [GO:0005615]; integral component of membrane [GO:0016021]; lipid droplet [GO:0005811]; mitochondrial outer membrane [GO:0005741]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886] apoptotic mitochondrial changes [GO:0008637]; negative regulation of ferroptosis [GO:0110076]; positive regulation of apoptotic process [GO:0043065]; regulation of apoptotic process [GO:0042981]; regulation of cellular response to oxidative stress [GO:1900407]; ubiquinone metabolic process [GO:0006743] DNA binding [GO:0003677]; electron-transferring-flavoprotein dehydrogenase activity [GO:0004174]; flavin adenine dinucleotide binding [GO:0050660]; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor [GO:0016655] GO:0003677; GO:0004174; GO:0005615; GO:0005634; GO:0005737; GO:0005739; GO:0005741; GO:0005811; GO:0005829; GO:0005886; GO:0006743; GO:0008637; GO:0016021; GO:0016655; GO:0042981; GO:0043065; GO:0050660; GO:0110076; GO:1900407 PF07992; IPR036188;IPR023753; 3 Q9H8Y8 Golgi reassembly-stacking protein 2 (GRS2) (Golgi phosphoprotein 6) (GOLPH6) (Golgi reassembly-stacking protein of 55 kDa) (GRASP55) (p59) Homo sapiens (Human) GSLWSKIS endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; Golgi membrane [GO:0000139]; membrane [GO:0016020] cell differentiation [GO:0030154]; establishment of protein localization to plasma membrane [GO:0061951]; Golgi organization [GO:0007030]; organelle assembly [GO:0070925]; organelle organization [GO:0006996]; response to endoplasmic reticulum stress [GO:0034976]; spermatogenesis [GO:0007283] GO:0000139; GO:0005789; GO:0005794; GO:0006996; GO:0007030; GO:0007283; GO:0016020; GO:0030154; GO:0034976; GO:0061951; GO:0070925 PF04495; IPR007583;IPR024958;IPR036034; 3 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 (Adenylate cyclase-inhibiting G alpha protein) Homo sapiens (Human) GTASSLVS cell body [GO:0044297]; centrosome [GO:0005813]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; extracellular exosome [GO:0070062]; extracellular vesicle [GO:1903561]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; synapse [GO:0045202] adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell cycle [GO:0007049]; cell division [GO:0051301]; cell population proliferation [GO:0008283]; gamma-aminobutyric acid signaling pathway [GO:0007214]; G protein-coupled acetylcholine receptor signaling pathway [GO:0007213]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; G protein-coupled receptor signaling pathway [GO:0007186]; negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process [GO:0140199]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of apoptotic signaling pathway [GO:2001234]; negative regulation of calcium ion-dependent exocytosis [GO:0045955]; negative regulation of protein tyrosine phosphatase activity [GO:1903614]; negative regulation of synaptic transmission [GO:0050805]; platelet activation [GO:0030168]; positive regulation of cell migration [GO:0030335]; positive regulation of cell population proliferation [GO:0008284]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of insulin receptor signaling pathway [GO:0046628]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of neural precursor cell proliferation [GO:2000179]; positive regulation of renal sodium excretion [GO:0035815]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of urine volume [GO:0035810]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; protein folding [GO:0006457]; regulation of calcium ion transport [GO:0051924]; response to nutrient [GO:0007584]; signal transduction [GO:0007165] G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872] GO:0001664; GO:0001973; GO:0003924; GO:0005525; GO:0005654; GO:0005737; GO:0005813; GO:0005829; GO:0005834; GO:0005886; GO:0006457; GO:0007049; GO:0007165; GO:0007186; GO:0007188; GO:0007189; GO:0007193; GO:0007194; GO:0007213; GO:0007214; GO:0007584; GO:0008283; GO:0008284; GO:0016020; GO:0030168; GO:0030335; GO:0030425; GO:0030496; GO:0031683; GO:0032930; GO:0033864; GO:0035810; GO:0035815; GO:0044297; GO:0045121; GO:0045202; GO:0045955; GO:0046628; GO:0046872; GO:0050805; GO:0051301; GO:0051924; GO:0070062; GO:0070374; GO:0140199; GO:1903561; GO:1903614; GO:1904707; GO:2000179; GO:2001234 PF00503; IPR001408;IPR001019;IPR011025;IPR027417; 3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3) Homo sapiens (Human) GAGASAEE centrosome [GO:0005813]; cytoplasm [GO:0005737]; extracellular exosome [GO:0070062]; Golgi apparatus [GO:0005794]; heterotrimeric G-protein complex [GO:0005834]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; membrane raft [GO:0045121]; midbody [GO:0030496]; plasma membrane [GO:0005886]; zymogen granule [GO:0042588] adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; brain development [GO:0007420]; cell cycle [GO:0007049]; cell division [GO:0051301]; dopamine receptor signaling pathway [GO:0007212]; G protein-coupled receptor signaling pathway [GO:0007186]; GTP metabolic process [GO:0046039]; negative regulation of adenylate cyclase activity [GO:0007194]; negative regulation of apoptotic signaling pathway [GO:2001234]; platelet activation [GO:0030168]; positive regulation of macroautophagy [GO:0016239]; positive regulation of NAD(P)H oxidase activity [GO:0033864]; positive regulation of superoxide anion generation [GO:0032930]; positive regulation of vascular associated smooth muscle cell proliferation [GO:1904707]; protein folding [GO:0006457]; vesicle fusion [GO:0006906] GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904] GO:0001664; GO:0003924; GO:0005525; GO:0005737; GO:0005765; GO:0005794; GO:0005813; GO:0005834; GO:0005886; GO:0006457; GO:0006906; GO:0007049; GO:0007186; GO:0007188; GO:0007193; GO:0007194; GO:0007212; GO:0007420; GO:0016020; GO:0016239; GO:0019003; GO:0019904; GO:0030168; GO:0030496; GO:0031683; GO:0031821; GO:0032794; GO:0032930; GO:0033864; GO:0042588; GO:0045121; GO:0046039; GO:0046872; GO:0051301; GO:0070062; GO:1904707; GO:2001234 PF00503; IPR001408;IPR001019;IPR011025;IPR027417; 3 P09471 Guanine nucleotide-binding protein G(o) subunit alpha Homo sapiens (Human) GSEQSSEA cell body [GO:0044297]; dendrite [GO:0030425]; heterotrimeric G-protein complex [GO:0005834]; myelin sheath [GO:0043209]; plasma membrane [GO:0005886] adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; aging [GO:0007568]; dopamine receptor signaling pathway [GO:0007212]; forebrain development [GO:0030900]; locomotory behavior [GO:0007626]; muscle contraction [GO:0006936]; negative regulation of calcium ion transport [GO:0051926]; neuron projection development [GO:0031175]; odontogenesis of dentin-containing tooth [GO:0042475]; positive regulation of GTPase activity [GO:0043547]; protein folding [GO:0006457]; regulation of heart contraction [GO:0008016]; response to cytokine [GO:0034097]; response to drug [GO:0042493]; response to hydrogen peroxide [GO:0042542]; response to morphine [GO:0043278]; Wnt signaling pathway, calcium modulating pathway [GO:0007223] corticotropin-releasing hormone receptor 1 binding [GO:0051430]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; G protein-coupled serotonin receptor binding [GO:0031821]; GTPase activating protein binding [GO:0032794]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; mu-type opioid receptor binding [GO:0031852] GO:0001664; GO:0003924; GO:0005525; GO:0005834; GO:0005886; GO:0006457; GO:0006936; GO:0007188; GO:0007212; GO:0007223; GO:0007568; GO:0007626; GO:0008016; GO:0030425; GO:0030900; GO:0031175; GO:0031683; GO:0031821; GO:0031852; GO:0032794; GO:0034097; GO:0042475; GO:0042493; GO:0042542; GO:0043209; GO:0043278; GO:0043547; GO:0044297; GO:0046872; GO:0051430; GO:0051926 PF00503; IPR001408;IPR001019;IPR011025;IPR027417; 3 P11488 Guanine nucleotide-binding protein G(t) subunit alpha-1 (Transducin alpha-1 chain) Homo sapiens (Human) GNASSIVQ apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; heterotrimeric G-protein complex [GO:0005834]; membrane [GO:0016020]; neuronal cell body [GO:0043025]; photoreceptor connecting cilium [GO:0032391]; photoreceptor disc membrane [GO:0097381]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; photoreceptor outer segment membrane [GO:0042622]; plasma membrane [GO:0005886] adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; cell population proliferation [GO:0008283]; cellular response to electrical stimulus [GO:0071257]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of light stimulus involved in visual perception [GO:0050908]; eye photoreceptor cell development [GO:0042462]; G protein-coupled adenosine receptor signaling pathway [GO:0001973]; negative regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051344]; phototransduction, visible light [GO:0007603]; positive regulation of cyclic-nucleotide phosphodiesterase activity [GO:0051343]; protein folding [GO:0006457]; regulation of rhodopsin mediated signaling pathway [GO:0022400]; response to light intensity [GO:0009642]; response to light stimulus [GO:0009416]; retina development in camera-type eye [GO:0060041]; rhodopsin mediated signaling pathway [GO:0016056]; sensory perception of umami taste [GO:0050917]; signal transduction [GO:0007165]; visual perception [GO:0007601] acyl binding [GO:0000035]; GDP binding [GO:0019003]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein kinase binding [GO:0019901] GO:0000035; GO:0001580; GO:0001664; GO:0001750; GO:0001917; GO:0001973; GO:0003924; GO:0005525; GO:0005829; GO:0005834; GO:0005886; GO:0006457; GO:0007165; GO:0007188; GO:0007193; GO:0007601; GO:0007603; GO:0008283; GO:0009416; GO:0009642; GO:0016020; GO:0016056; GO:0016324; GO:0019003; GO:0019901; GO:0022400; GO:0031683; GO:0032391; GO:0042462; GO:0042622; GO:0043025; GO:0046872; GO:0050908; GO:0050917; GO:0051343; GO:0051344; GO:0060041; GO:0071257; GO:0097381 PF00503; IPR001408;IPR001019;IPR011025;IPR027417; 3 P19087 Guanine nucleotide-binding protein G(t) subunit alpha-2 (Transducin alpha-2 chain) Homo sapiens (Human) GSGASKNT heterotrimeric G-protein complex [GO:0005834]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; photoreceptor outer segment membrane [GO:0042622]; plasma membrane [GO:0005886] adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; detection of light stimulus involved in visual perception [GO:0050908]; G protein-coupled receptor signaling pathway [GO:0007186]; phototransduction [GO:0007602]; protein folding [GO:0006457]; visual perception [GO:0007601]; Wnt signaling pathway, calcium modulating pathway [GO:0007223] G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled photoreceptor activity [GO:0008020]; G protein-coupled receptor binding [GO:0001664]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872] GO:0001580; GO:0001664; GO:0001750; GO:0001917; GO:0003924; GO:0005525; GO:0005834; GO:0005886; GO:0006457; GO:0007186; GO:0007188; GO:0007223; GO:0007601; GO:0007602; GO:0008020; GO:0031683; GO:0042622; GO:0046872; GO:0050908 PF00503; IPR001408;IPR001019;IPR011025;IPR027417; 3 A8MTJ3 Guanine nucleotide-binding protein G(t) subunit alpha-3 (Gustducin alpha-3 chain) Homo sapiens (Human) GSVLGLCS acrosomal vesicle [GO:0001669]; apical plasma membrane [GO:0016324]; axoneme [GO:0005930]; heterotrimeric G-protein complex [GO:0005834]; photoreceptor inner segment [GO:0001917]; photoreceptor outer segment [GO:0001750]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; detection of chemical stimulus involved in sensory perception of bitter taste [GO:0001580]; G protein-coupled receptor signaling pathway [GO:0007186]; platelet activation [GO:0030168]; protein folding [GO:0006457]; response to nicotine [GO:0035094]; sensory perception of sweet taste [GO:0050916]; sensory perception of umami taste [GO:0050917] G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872] GO:0001580; GO:0001664; GO:0001669; GO:0001750; GO:0001917; GO:0003924; GO:0005525; GO:0005834; GO:0005886; GO:0005930; GO:0006457; GO:0007186; GO:0007188; GO:0007193; GO:0016324; GO:0030168; GO:0031683; GO:0032991; GO:0035094; GO:0046872; GO:0050916; GO:0050917 PF00503; IPR001408;IPR001019;IPR011025;IPR027417; 3 Q8CFC9 Leucine zipper putative tumor suppressor 1 (PSD-Zip70) Rattus norvegicus (Rat) GDVLSTHL apical plasma membrane [GO:0016324]; cell body [GO:0044297]; cytoplasm [GO:0005737]; dendritic shaft [GO:0043198]; dendritic spine [GO:0043197]; neuron projection [GO:0043005]; postsynaptic density [GO:0014069]; postsynaptic membrane [GO:0045211]; synapse [GO:0045202] mitotic cell cycle phase transition [GO:0044772]; negative regulation of macroautophagy [GO:0016242]; regulation of dendrite morphogenesis [GO:0048814]; regulation of synaptic plasticity [GO:0048167] microtubule binding [GO:0008017] GO:0005737; GO:0008017; GO:0014069; GO:0016242; GO:0016324; GO:0043005; GO:0043197; GO:0043198; GO:0044297; GO:0044772; GO:0045202; GO:0045211; GO:0048167; GO:0048814 IPR033293; 3 P07611 Myristoylated protein G9 (Protein F1) Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR)) GCTVSAED integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036] fusion of virus membrane with host plasma membrane [GO:0019064] GO:0016021; GO:0019031; GO:0019064; GO:0055036 PF03003; IPR004251; 3 Q7Z494 Nephrocystin-3 Homo sapiens (Human) GCTLSAEE cilium [GO:0005929]; cytosol [GO:0005829]; extracellular region [GO:0005576] atrial septum development [GO:0003283]; cilium assembly [GO:0060271]; convergent extension involved in gastrulation [GO:0060027]; determination of intestine left/right asymmetry [GO:0071908]; determination of left/right symmetry [GO:0007368]; determination of liver left/right asymmetry [GO:0071910]; determination of pancreatic left/right asymmetry [GO:0035469]; determination of stomach left/right asymmetry [GO:0071909]; epithelial cilium movement involved in determination of left/right asymmetry [GO:0060287]; heart looping [GO:0001947]; kidney development [GO:0001822]; kidney morphogenesis [GO:0060993]; lung development [GO:0030324]; maintenance of animal organ identity [GO:0048496]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; photoreceptor cell maintenance [GO:0045494]; regulation of planar cell polarity pathway involved in neural tube closure [GO:2000167]; regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000095]; ureter development [GO:0072189]; Wnt signaling pathway [GO:0016055] GO:0001822; GO:0001947; GO:0003283; GO:0005576; GO:0005829; GO:0005929; GO:0007368; GO:0016055; GO:0030324; GO:0035469; GO:0045494; GO:0048496; GO:0060027; GO:0060271; GO:0060287; GO:0060993; GO:0071908; GO:0071909; GO:0071910; GO:0072189; GO:0090090; GO:2000095; GO:2000167 PF13176; IPR027417;IPR013026;IPR011990;IPR019734; 3 P11078 Outer capsid protein mu-1 (Mu1) [Cleaved into: Outer capsid protein mu-1N; Outer capsid protein mu-1C] Reovirus type 3 (strain Dearing) (T3D) (Mammalian orthoreovirus 3) GSVLSTDS host cell endoplasmic reticulum [GO:0044165]; host cell mitochondrion [GO:0033650]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; viral outer capsid [GO:0039624] pathogenesis [GO:0009405]; permeabilization of host organelle membrane involved in viral entry into host cell [GO:0039665]; viral entry via permeabilization of inner membrane [GO:0099008] host cell surface binding [GO:0046812] GO:0009405; GO:0016020; GO:0020002; GO:0033650; GO:0039624; GO:0039665; GO:0044165; GO:0046812; GO:0099008 PF05993; IPR009113;IPR036256;IPR015961;IPR015962;IPR015960; 3 A4GNA8 Phosphatidylserine decarboxylase proenzyme 3 (EC 4.1.1.65) [Cleaved into: Phosphatidylserine decarboxylase 3 beta chain; Phosphatidylserine decarboxylase 3 alpha chain] Arabidopsis thaliana (Mouse-ear cress) GSRWSSEE cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789] phosphatidylethanolamine biosynthetic process [GO:0006646]; protein autoprocessing [GO:0016540] calcium ion binding [GO:0005509]; phosphatidylserine decarboxylase activity [GO:0004609] GO:0004609; GO:0005509; GO:0005783; GO:0005789; GO:0005829; GO:0006646; GO:0016540 PF13833;PF02666; IPR035892;IPR011992;IPR018247;IPR002048;IPR003817;IPR033177;IPR033179; 3 Q96TA1 Protein Niban 2 (Meg-3) (Melanoma invasion by ERK) (MINERVA) (Niban-like protein 1) (Protein FAM129B) Homo sapiens (Human) GSNSSRIG adherens junction [GO:0005912]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; plasma membrane [GO:0005886] axon guidance [GO:0007411]; cell differentiation [GO:0030154]; gonadotropin secretion [GO:0032274]; hypomethylation of CpG island [GO:0044029]; negative regulation of angiogenesis [GO:0016525]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of DNA biosynthetic process [GO:2000279]; negative regulation of Notch signaling pathway [GO:0045746]; negative regulation of transcription, DNA-templated [GO:0045892]; negative regulation of vascular endothelial growth factor receptor signaling pathway [GO:0030948]; positive regulation of embryonic development [GO:0040019]; positive regulation of skeletal muscle fiber development [GO:0048743]; positive regulation of transcription, DNA-templated [GO:0045893]; positive regulation of transcription regulatory region DNA binding [GO:2000679] cadherin binding [GO:0045296]; transcription coactivator activity [GO:0003713] GO:0003713; GO:0005634; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0005912; GO:0007411; GO:0008285; GO:0016525; GO:0030154; GO:0030948; GO:0032274; GO:0040019; GO:0043066; GO:0044029; GO:0045296; GO:0045746; GO:0045892; GO:0045893; GO:0048743; GO:0070062; GO:2000279; GO:2000679 IPR026088;IPR011993;IPR001849; 3 Q96MG8 Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 Homo sapiens (Human) GNGNSTET cytoplasm [GO:0005737]; membrane [GO:0016020] protein-L-isoaspartate (D-aspartate) O-methyltransferase activity [GO:0004719] GO:0004719; GO:0005737; GO:0016020 IPR000682;IPR029063; 3 Q9CB01 Ras-related protein RABF1 (AtRABF1) (Ras-related protein Ara-6) (Ras-related protein Rab5C) (AtRab5C) Arabidopsis thaliana (Mouse-ear cress) GQGKSREE cytoplasmic side of endosome membrane [GO:0010009]; cytosol [GO:0005829]; early endosome [GO:0005769]; early endosome membrane [GO:0031901]; endomembrane system [GO:0012505]; endoplasmic reticulum [GO:0005783]; endosome [GO:0005768]; plasma membrane [GO:0005886] early endosome to late endosome transport [GO:0045022]; endocytosis [GO:0006897]; intracellular protein transport [GO:0006886] GTPase activity [GO:0003924]; GTP binding [GO:0005525] GO:0003924; GO:0005525; GO:0005768; GO:0005769; GO:0005783; GO:0005829; GO:0005886; GO:0006886; GO:0006897; GO:0010009; GO:0012505; GO:0031901; GO:0045022 PF00071; IPR027417;IPR005225;IPR001806; 3 P18541 RING finger protein Z (Protein Z) (Zinc-binding protein) Lymphocytic choriomeningitis virus (strain Armstrong) (LCMV) GSILSRRI host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; virion [GO:0019012] viral budding from plasma membrane [GO:0046761]; viral budding via host ESCRT complex [GO:0039702] RNA binding [GO:0003723]; zinc ion binding [GO:0008270] GO:0003723; GO:0008270; GO:0016020; GO:0019012; GO:0020002; GO:0039702; GO:0044220; GO:0046761 PF03854; IPR024183;IPR038485;IPR003224; 3 Q9NRX5 Serine incorporator 1 (Tumor differentially expressed protein 1-like) (Tumor differentially expressed protein 2) Homo sapiens (Human) GGGVSVEL endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; plasma membrane [GO:0005886] membrane biogenesis [GO:0044091]; phosphatidylserine metabolic process [GO:0006658]; phospholipid biosynthetic process [GO:0008654]; positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity [GO:1904219]; positive regulation of serine C-palmitoyltransferase activity [GO:1904222]; sphingolipid metabolic process [GO:0006665] enzyme binding [GO:0019899]; protein-macromolecule adaptor activity [GO:0030674] GO:0005789; GO:0005886; GO:0006658; GO:0006665; GO:0008654; GO:0016020; GO:0016021; GO:0019899; GO:0030674; GO:0044091; GO:1904219; GO:1904222 PF03348; IPR029557;IPR005016; 3 Q96SL1 Solute carrier family 49 member 4 (Disrupted in renal cancer protein 2) (Disrupted in renal carcinoma protein 2) Homo sapiens (Human) GAGSSTEQ integral component of membrane [GO:0016021]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765] GO:0005765; GO:0016021; GO:0043231 IPR036259; 3 O15121 Sphingolipid delta(4)-desaturase DES1 (EC 1.14.19.17) (Cell migration-inducing gene 15 protein) (Degenerative spermatocyte homolog 1) (Dihydroceramide desaturase-1) (Membrane lipid desaturase) Homo sapiens (Human) GLVWSLIS endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of plasma membrane [GO:0005887]; membrane [GO:0016020]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886]; specific granule membrane [GO:0035579] ceramide biosynthetic process [GO:0046513]; myelin maintenance [GO:0043217]; neutrophil degranulation [GO:0043312]; sphingolipid biosynthetic process [GO:0030148]; unsaturated fatty acid biosynthetic process [GO:0006636] electron transfer activity [GO:0009055]; retinol isomerase activity [GO:0050251]; sphingolipid delta-4 desaturase activity [GO:0042284] GO:0005739; GO:0005783; GO:0005789; GO:0005886; GO:0005887; GO:0006636; GO:0009055; GO:0016020; GO:0030148; GO:0031966; GO:0035579; GO:0042284; GO:0043217; GO:0043312; GO:0046513; GO:0050251 PF00487;PF08557; IPR031196;IPR011388;IPR005804;IPR013866; 3 Q9H6Q3 Src-like-adapter 2 (Modulator of antigen receptor signaling) (MARS) (Src-like adapter protein 2) (SLAP-2) Homo sapiens (Human) GGAVSAGE cytoplasm [GO:0005737]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; nucleoplasm [GO:0005654]; phosphatidylinositol 3-kinase complex [GO:0005942]; plasma membrane [GO:0005886] antigen receptor-mediated signaling pathway [GO:0050851]; B cell mediated immunity [GO:0019724]; cytokine-mediated signaling pathway [GO:0019221]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol phosphorylation [GO:0046854]; regulation of immune response [GO:0050776]; T cell activation [GO:0042110] GO:0000122; GO:0005654; GO:0005737; GO:0005770; GO:0005794; GO:0005829; GO:0005886; GO:0005942; GO:0010008; GO:0019221; GO:0019724; GO:0035591; GO:0042110; GO:0043231; GO:0046854; GO:0046935; GO:0047485; GO:0050776; GO:0050849; GO:0050851; GO:0050860 PF00017;PF00018; IPR000980;IPR036860;IPR036028;IPR001452;IPR035054;IPR035052; 3 Q8R4L0 Src-like-adapter 2 (Src-like adapter protein 2) (SLAP-2) Mus musculus (Mouse) GSQVSVES cytoplasmic vesicle [GO:0031410]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; nucleoplasm [GO:0005654]; phosphatidylinositol 3-kinase complex [GO:0005942]; plasma membrane [GO:0005886] adaptive immune response [GO:0002250]; negative regulation of calcium-mediated signaling [GO:0050849]; negative regulation of T cell receptor signaling pathway [GO:0050860]; negative regulation of transcription by RNA polymerase II [GO:0000122]; phosphatidylinositol phosphorylation [GO:0046854]; T cell activation [GO:0042110] 1-phosphatidylinositol-3-kinase regulator activity [GO:0046935]; protein N-terminus binding [GO:0047485]; signaling adaptor activity [GO:0035591] GO:0000122; GO:0002250; GO:0005654; GO:0005770; GO:0005794; GO:0005886; GO:0005942; GO:0031410; GO:0035591; GO:0042110; GO:0043231; GO:0046854; GO:0046935; GO:0047485; GO:0050849; GO:0050860 PF00017; IPR000980;IPR036860;IPR036028;IPR001452;IPR035054;IPR035052; 3 P08631 Tyrosine-protein kinase HCK (EC 2.7.10.2) (Hematopoietic cell kinase) (Hemopoietic cell kinase) (p59-HCK/p60-HCK) (p59Hck) (p61Hck) Homo sapiens (Human) GSRVSRED caveola [GO:0005901]; cell projection [GO:0042995]; cytoskeleton [GO:0005856]; cytosol [GO:0005829]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; lysosome [GO:0005764]; nucleus [GO:0005634]; plasma membrane [GO:0005886]; transport vesicle [GO:0030133] cell adhesion [GO:0007155]; cell differentiation [GO:0030154]; cytokine-mediated signaling pathway [GO:0019221]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; inflammatory response [GO:0006954]; innate immune response [GO:0045087]; innate immune response-activating signal transduction [GO:0002758]; integrin-mediated signaling pathway [GO:0007229]; interferon-gamma-mediated signaling pathway [GO:0060333]; leukocyte degranulation [GO:0043299]; leukocyte migration involved in immune response [GO:0002522]; lipopolysaccharide-mediated signaling pathway [GO:0031663]; mesoderm development [GO:0007498]; negative regulation of apoptotic process [GO:0043066]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; peptidyl-tyrosine phosphorylation [GO:0018108]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament polymerization [GO:0030838]; positive regulation of cell population proliferation [GO:0008284]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of DNA-binding transcription factor activity [GO:0051090]; regulation of inflammatory response [GO:0050727]; regulation of phagocytosis [GO:0050764]; regulation of podosome assembly [GO:0071801]; respiratory burst after phagocytosis [GO:0045728]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] GO:0001784; GO:0002522; GO:0002758; GO:0002862; GO:0004713; GO:0004714; GO:0004715; GO:0005102; GO:0005524; GO:0005634; GO:0005764; GO:0005794; GO:0005829; GO:0005856; GO:0005886; GO:0005901; GO:0005925; GO:0006468; GO:0006954; GO:0007155; GO:0007169; GO:0007229; GO:0007498; GO:0008284; GO:0008360; GO:0018108; GO:0019221; GO:0030133; GO:0030154; GO:0030838; GO:0031234; GO:0031663; GO:0038096; GO:0042995; GO:0043066; GO:0043231; GO:0043299; GO:0045087; GO:0045728; GO:0046777; GO:0050690; GO:0050727; GO:0050764; GO:0051090; GO:0060333; GO:0071801; GO:2000251 PF07714;PF00017;PF00018; IPR035851;IPR011009;IPR000719;IPR017441;IPR001245;IPR000980;IPR036860;IPR036028;IPR001452;IPR008266;IPR020635; 4 P40327 26S proteasome regulatory subunit 4 homolog (Tat-binding homolog 5) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) GNRGSSTS cytoplasm [GO:0005737]; nucleus [GO:0005634]; proteasome regulatory particle, base subcomplex [GO:0008540] cellular protein-containing complex localization [GO:0034629]; nonfunctional rRNA decay [GO:0070651]; peptide catabolic process [GO:0043171]; positive regulation of protein catabolic process [GO:0045732]; proteasome regulatory particle assembly [GO:0070682]; ubiquitin-dependent protein catabolic process [GO:0006511] ATPase activity [GO:0016887]; ATP binding [GO:0005524]; proteasome-activating ATPase activity [GO:0036402]; TBP-class protein binding [GO:0017025] GO:0005524; GO:0005634; GO:0005737; GO:0006511; GO:0008540; GO:0016887; GO:0017025; GO:0034629; GO:0036402; GO:0043171; GO:0045732; GO:0070651; GO:0070682 PF00004;PF17862;PF16450; IPR005937;IPR003593;IPR041569;IPR003959;IPR003960;IPR027417;IPR032501; 4 P84077 ADP-ribosylation factor 1 Homo sapiens (Human) GNAPSHSS cell leading edge [GO:0031252]; COPI-coated vesicle [GO:0030137]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; glutamatergic synapse [GO:0098978]; Golgi membrane [GO:0000139]; late endosome [GO:0005770]; neuron projection [GO:0043005]; perinuclear region of cytoplasm [GO:0048471]; peroxisomal membrane [GO:0005778]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; protein-containing complex [GO:0032991]; sarcomere [GO:0030017]; trans-Golgi network [GO:0005802] actin filament organization [GO:0007015]; antigen processing and presentation of exogenous peptide antigen via MHC class II [GO:0019886]; cellular copper ion homeostasis [GO:0006878]; cellular response to virus [GO:0098586]; dendritic spine organization [GO:0097061]; Golgi to transport vesicle transport [GO:0055108]; interleukin-12-mediated signaling pathway [GO:0035722]; intracellular protein transport [GO:0006886]; long-term synaptic depression [GO:0060292]; lysosomal membrane organization [GO:0097212]; mitotic cleavage furrow ingression [GO:1990386]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of endocytosis [GO:0045807]; positive regulation of ER to Golgi vesicle-mediated transport [GO:1902953]; positive regulation of late endosome to lysosome transport [GO:1902824]; positive regulation of protein secretion [GO:0050714]; positive regulation of sodium ion transmembrane transport [GO:1902307]; post-Golgi vesicle-mediated transport [GO:0006892]; postsynaptic actin cytoskeleton organization [GO:0098974]; regulation of Arp2/3 complex-mediated actin nucleation [GO:0034315]; regulation of defense response to virus by virus [GO:0050690]; regulation of phospholipid metabolic process [GO:1903725]; regulation of receptor internalization [GO:0002090]; synaptic vesicle budding [GO:0070142]; very-low-density lipoprotein particle assembly [GO:0034379]; vesicle-mediated transport [GO:0016192] GDP binding [GO:0019003]; GTP binding [GO:0005525]; magnesium ion binding [GO:0000287]; phospholipase D activator activity [GO:1990583]; protein domain specific binding [GO:0019904]; RNA binding [GO:0003723] GO:0000139; GO:0000287; GO:0002090; GO:0003723; GO:0005525; GO:0005770; GO:0005778; GO:0005802; GO:0005829; GO:0005886; GO:0005925; GO:0006661; GO:0006878; GO:0006886; GO:0006892; GO:0007015; GO:0014069; GO:0016192; GO:0019003; GO:0019886; GO:0019904; GO:0030017; GO:0030137; GO:0031252; GO:0032991; GO:0034315; GO:0034379; GO:0035722; GO:0043005; GO:0045807; GO:0045956; GO:0048471; GO:0050690; GO:0050714; GO:0055108; GO:0060292; GO:0060999; GO:0070062; GO:0070142; GO:0097061; GO:0097212; GO:0098586; GO:0098974; GO:0098978; GO:1902307; GO:1902824; GO:1902953; GO:1903725; GO:1990386; GO:1990583 PF00025; IPR027417;IPR005225;IPR006689; 4 P61204 ADP-ribosylation factor 3 Homo sapiens (Human) GNAASGGS extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] intracellular protein transport [GO:0006886]; phosphatidylinositol biosynthetic process [GO:0006661]; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum [GO:0006890]; vesicle-mediated transport [GO:0016192] GTPase activity [GO:0003924]; GTP binding [GO:0005525] GO:0000139; GO:0003924; GO:0005525; GO:0005886; GO:0006661; GO:0006886; GO:0006890; GO:0016192; GO:0048471; GO:0070062 PF00025; IPR027417;IPR005225;IPR006689; 4 P40616 ADP-ribosylation factor-like protein 1 Homo sapiens (Human) GNAGSMDS cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; trans-Golgi network [GO:0005802]; trans-Golgi network membrane [GO:0032588] activation of phospholipase D activity [GO:0031584]; Golgi organization [GO:0007030]; intracellular protein transport [GO:0006886]; protein localization to Golgi apparatus [GO:0034067]; retrograde transport, endosome to Golgi [GO:0042147]; toxin metabolic process [GO:0009404]; vesicle-mediated transport [GO:0016192] enzyme activator activity [GO:0008047]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872]; protein domain specific binding [GO:0019904] GO:0003924; GO:0005525; GO:0005737; GO:0005794; GO:0005802; GO:0005829; GO:0006886; GO:0007030; GO:0008047; GO:0009404; GO:0016192; GO:0019904; GO:0031584; GO:0032588; GO:0034067; GO:0042147; GO:0046872 PF00025; IPR027417;IPR005225;IPR006689; 4 P38116 ADP-ribosylation factor-like protein 1 (Arf-like GTPase 1) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) GNIFANLF cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; trans-Golgi network [GO:0005802] cellular protein-containing complex localization [GO:0034629]; cytoplasm to vacuole transport by the Cvt pathway [GO:0032258]; endocytosis [GO:0006897]; Golgi to plasma membrane protein transport [GO:0043001]; intracellular protein transport [GO:0006886]; macroautophagy [GO:0016236]; protein localization to Golgi apparatus [GO:0034067]; protein localization to phagophore assembly site [GO:0034497]; protein targeting to vacuole [GO:0006623]; response to endoplasmic reticulum stress [GO:0034976]; vesicle-mediated transport [GO:0016192] GTPase activity [GO:0003924]; GTP binding [GO:0005525] GO:0003924; GO:0005525; GO:0005794; GO:0005802; GO:0005829; GO:0006623; GO:0006886; GO:0006897; GO:0016192; GO:0016236; GO:0032258; GO:0034067; GO:0034497; GO:0034629; GO:0034976; GO:0043001 PF00025; IPR027417;IPR005225;IPR006689; 4 Q96KC2 ADP-ribosylation factor-like protein 5B (ADP-ribosylation factor-like protein 8) Homo sapiens (Human) GNIFGNLL trans-Golgi network [GO:0005802] intracellular protein transport [GO:0006886]; protein localization to Golgi membrane [GO:1903292]; vesicle-mediated transport [GO:0016192] GTP binding [GO:0005525] GO:0005525; GO:0005802; GO:0006886; GO:0016192; GO:1903292 PF00025; IPR027417;IPR005225;IPR006689; 4 P63098 Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1) Homo sapiens (Human) GNNFSSVS calcineurin complex [GO:0005955]; cytosol [GO:0005829]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; sarcolemma [GO:0042383] calcineurin-NFAT signaling cascade [GO:0033173]; Fc-epsilon receptor signaling pathway [GO:0038095]; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway [GO:1900740]; positive regulation of transcription by RNA polymerase II [GO:0045944]; Wnt signaling pathway, calcium modulating pathway [GO:0007223] calcium-dependent protein serine/threonine phosphatase activity [GO:0004723]; calcium-dependent protein serine/threonine phosphatase regulator activity [GO:0008597]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; cyclosporin A binding [GO:0016018]; phosphatase binding [GO:0019902]; protein domain specific binding [GO:0019904] GO:0004723; GO:0005509; GO:0005516; GO:0005654; GO:0005739; GO:0005829; GO:0005955; GO:0007223; GO:0008597; GO:0016018; GO:0019902; GO:0019904; GO:0033173; GO:0038095; GO:0042383; GO:0045944; GO:1900740 PF13499; IPR015757;IPR011992;IPR018247;IPR002048; 4 Q96LZ3 Calcineurin subunit B type 2 (Calcineurin B-like protein) (CBLP) (Calcineurin BII) (CNBII) (PPP3R1-like) (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) Homo sapiens (Human) GNIFSSMF calcium-dependent protein serine/threonine phosphatase regulator activity [GO:0008597]; calcium ion binding [GO:0005509] GO:0005509; GO:0008597 PF13499; IPR015757;IPR011992;IPR018247;IPR002048; 4 P21137 cAMP-dependent protein kinase catalytic subunit (PKA C) (EC 2.7.11.11) Caenorhabditis elegans GLIFAKLW cAMP-dependent protein kinase complex [GO:0005952]; nucleus [GO:0005634] positive regulation of oocyte maturation [GO:1900195]; protein kinase A signaling [GO:0010737]; protein phosphorylation [GO:0006468] AMP-activated protein kinase activity [GO:0004679]; ATP binding [GO:0005524]; cAMP-dependent protein kinase activity [GO:0004691]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0004679; GO:0004691; GO:0005524; GO:0005634; GO:0005952; GO:0006468; GO:0010737; GO:0106310; GO:0106311; GO:1900195 PF00069; IPR011009;IPR000719;IPR017441;IPR008271;IPR044109; 4 Q13237 cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII) Homo sapiens (Human) GNISSSGG apical plasma membrane [GO:0016324]; cytosol [GO:0005829]; nuclear membrane [GO:0031965] MAPK cascade [GO:0000165]; negative regulation of chloride transport [GO:2001226]; peptidyl-serine autophosphorylation [GO:0036289]; protein localization to plasma membrane [GO:0072659]; protein phosphorylation [GO:0006468]; signal transduction [GO:0007165]; tetrahydrobiopterin metabolic process [GO:0046146] ATP binding [GO:0005524]; cGMP binding [GO:0030553]; cGMP-dependent protein kinase activity [GO:0004692]; identical protein binding [GO:0042802]; protein kinase activity [GO:0004672]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0000165; GO:0004672; GO:0004692; GO:0005524; GO:0005829; GO:0006468; GO:0007165; GO:0016324; GO:0030553; GO:0031965; GO:0036289; GO:0042802; GO:0046146; GO:0072659; GO:0106310; GO:0106311; GO:2001226 PF00027;PF00069; IPR000961;IPR002374;IPR018490;IPR018488;IPR000595;IPR011009;IPR000719;IPR017441;IPR014710;IPR008271;IPR035014; 4 Q923S6 E3 ubiquitin-protein ligase NEURL1 (EC 2.3.2.27) (Neuralized-like protein 1A) (m-neu1) (m-neuralized 1) (Neuralized1) (RING-type E3 ubiquitin transferase NEURL1) Mus musculus (Mouse) GNSMKSTS apical dendrite [GO:0097440]; cytoplasm [GO:0005737]; dendritic spine [GO:0043197]; perikaryon [GO:0043204]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] brain development [GO:0007420]; cellular response to amino acid stimulus [GO:0071230]; flagellated sperm motility [GO:0030317]; lactation [GO:0007595]; negative regulation of cell population proliferation [GO:0008285]; negative regulation of Notch signaling pathway [GO:0045746]; nervous system development [GO:0007399]; Notch signaling pathway [GO:0007219]; positive regulation of apoptotic process [GO:0043065]; positive regulation of dendritic spine development [GO:0060999]; positive regulation of epidermal growth factor-activated receptor activity [GO:0045741]; positive regulation of filopodium assembly [GO:0051491]; positive regulation of long-term neuronal synaptic plasticity [GO:0048170]; positive regulation of synapse maturation [GO:0090129]; protein monoubiquitination [GO:0006513]; skeletal muscle tissue development [GO:0007519]; sperm axoneme assembly [GO:0007288] metal ion binding [GO:0046872]; translation factor activity, non-nucleic acid binding [GO:0045183]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] GO:0004842; GO:0005737; GO:0005886; GO:0006513; GO:0007219; GO:0007288; GO:0007399; GO:0007420; GO:0007519; GO:0007595; GO:0008285; GO:0014069; GO:0030317; GO:0043065; GO:0043197; GO:0043204; GO:0045183; GO:0045741; GO:0045746; GO:0046872; GO:0048170; GO:0048471; GO:0051491; GO:0060999; GO:0061630; GO:0071230; GO:0090129; GO:0097440 PF07177; IPR043136;IPR037962;IPR006573;IPR001841;IPR013083; 4 Q96PY5 Formin-like protein 2 (Formin homology 2 domain-containing protein 2) Homo sapiens (Human) GGFFSSIF cytosol [GO:0005829] cell migration [GO:0016477]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; regulation of cell morphogenesis [GO:0022604]; regulation of cell shape [GO:0008360] actin filament binding [GO:0051015]; cadherin binding [GO:0045296]; small GTPase binding [GO:0031267] GO:0005829; GO:0007010; GO:0008360; GO:0016477; GO:0022604; GO:0030866; GO:0031267; GO:0045296; GO:0051015 PF06367;PF06371;PF02181; IPR016024;IPR014767;IPR015425;IPR042201;IPR010472;IPR043592;IPR027656;IPR014768;IPR010473; 4 Q8IVF7 Formin-like protein 3 (Formin homology 2 domain-containing protein 3) (WW domain-binding protein 3) (WBP-3) Homo sapiens (Human) GCGPSSGR cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; intracellular membrane-bounded organelle [GO:0043231]; plasma membrane [GO:0005886] angiogenesis [GO:0001525]; cell migration [GO:0016477]; cortical actin cytoskeleton organization [GO:0030866]; cytoskeleton organization [GO:0007010]; regulation of cell shape [GO:0008360] actin filament binding [GO:0051015]; GTPase activating protein binding [GO:0032794]; small GTPase binding [GO:0031267] GO:0001525; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0007010; GO:0008360; GO:0016477; GO:0030866; GO:0031267; GO:0032794; GO:0043231; GO:0051015 PF06367;PF06371;PF02181; IPR016024;IPR015425;IPR042201;IPR010472;IPR043592;IPR027655;IPR014768;IPR010473; 4 Q08358 Polyprotein pp220 (220 kDa polyprotein) [Cleaved into: p34; p14; p37; p150] African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V) (ASFV) GQGVSSGQ host cell nucleus [GO:0042025]; host cell perinuclear region of cytoplasm [GO:0044220]; virion [GO:0019012] viral capsid assembly [GO:0019069] GO:0019012; GO:0019069; GO:0042025; GO:0044220 4 Q9S752 Probable E3 ubiquitin-protein ligase LOG2 (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase LOG2) (Protein LOSS OF GDU2) (RING finger protein 215) Arabidopsis thaliana (Mouse-ear cress) GCGCSSHP plasma membrane [GO:0005886] abscisic acid-activated signaling pathway involved in stomatal movement [GO:1901527]; amino acid homeostasis [GO:0080144]; protein ubiquitination [GO:0016567]; response to abscisic acid [GO:0009737] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] GO:0004842; GO:0005886; GO:0009737; GO:0016567; GO:0046872; GO:0061630; GO:0080144; GO:1901527 IPR001841;IPR013083; 4 O88778 Protein bassoon Rattus norvegicus (Rat) GNEASYPA axon [GO:0030424]; axon cytoplasm [GO:1904115]; cell surface [GO:0009986]; cytoskeleton of presynaptic active zone [GO:0048788]; dendrite [GO:0030425]; excitatory synapse [GO:0060076]; extrinsic component of membrane [GO:0019898]; GABA-ergic synapse [GO:0098982]; glutamatergic synapse [GO:0098978]; Golgi-associated vesicle [GO:0005798]; hippocampal mossy fiber to CA3 synapse [GO:0098686]; inhibitory synapse [GO:0060077]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]; piccolo-bassoon transport vesicle [GO:1990257]; postsynaptic density [GO:0014069]; presynapse [GO:0098793]; presynaptic active zone [GO:0048786]; presynaptic active zone cytoplasmic component [GO:0098831]; ribbon synapse [GO:0097470]; Schaffer collateral - CA1 synapse [GO:0098685]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; synaptic vesicle membrane [GO:0030672]; trans-Golgi network [GO:0005802] axo-dendritic transport [GO:0008088]; cytoskeleton organization [GO:0007010]; presynapse to nucleus signaling pathway [GO:0099526]; presynaptic active zone assembly [GO:1904071]; protein localization to synapse [GO:0035418]; regulation of synaptic vesicle cycle [GO:0098693]; regulation of ubiquitin protein ligase activity [GO:1904666]; retrograde axonal transport [GO:0008090]; synapse organization [GO:0050808] dynein light chain binding [GO:0045503]; metal ion binding [GO:0046872]; structural constituent of presynaptic active zone [GO:0098882]; transcription corepressor binding [GO:0001222] GO:0001222; GO:0005798; GO:0005802; GO:0007010; GO:0008021; GO:0008088; GO:0008090; GO:0009986; GO:0014069; GO:0019898; GO:0030424; GO:0030425; GO:0030672; GO:0035418; GO:0043025; GO:0044306; GO:0045202; GO:0045503; GO:0046872; GO:0048786; GO:0048788; GO:0050808; GO:0060076; GO:0060077; GO:0097470; GO:0098685; GO:0098686; GO:0098693; GO:0098793; GO:0098831; GO:0098882; GO:0098978; GO:0098982; GO:0099526; GO:1904071; GO:1904115; GO:1904666; GO:1990257 PF05715; IPR030627;IPR011011;IPR008899;IPR013083; 4 G5EBX9 Serine/threonine-protein phosphatase with EF-hands pef-1 (CePPEF) (EC 3.1.3.16) (Phosphatase with EF hands 1) Caenorhabditis elegans GNEASLEG axon [GO:0030424]; cilium [GO:0005929]; cytosol [GO:0005829]; dendrite [GO:0030425]; neuronal cell body [GO:0043025]; nucleus [GO:0005634]; perikaryon [GO:0043204]; plasma membrane [GO:0005886] detection of stimulus involved in sensory perception [GO:0050906] calcium ion binding [GO:0005509]; iron ion binding [GO:0005506]; manganese ion binding [GO:0030145]; protein serine/threonine phosphatase activity [GO:0004722]; protein serine phosphatase activity [GO:0106306]; protein threonine phosphatase activity [GO:0106307] GO:0004722; GO:0005506; GO:0005509; GO:0005634; GO:0005829; GO:0005886; GO:0005929; GO:0030145; GO:0030424; GO:0030425; GO:0043025; GO:0043204; GO:0050906; GO:0106306; GO:0106307 PF13202;PF00149;PF08321; IPR004843;IPR011992;IPR018247;IPR002048;IPR029052;IPR013235;IPR012008;IPR006186; 4 Q60898 Src-like-adapter (Src-like-adapter protein 1) (SLAP-1) (mSLAP) Mus musculus (Mouse) GNEASYPL dendritic spine [GO:0043197]; endosome [GO:0005768]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; focal adhesion [GO:0005925] cell differentiation [GO:0030154]; innate immune response [GO:0045087]; regulation of signal transduction [GO:0009966]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102] GO:0004713; GO:0004715; GO:0005102; GO:0005768; GO:0005925; GO:0007169; GO:0009966; GO:0030154; GO:0031234; GO:0043197; GO:0045087 PF00017;PF00018; IPR000980;IPR036860;IPR036028;IPR001452;IPR035055;IPR035052;IPR035596; 4 P06239 Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK) Homo sapiens (Human) GNLESAEG cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; immunological synapse [GO:0001772]; membrane raft [GO:0045121]; pericentriolar material [GO:0000242]; plasma membrane [GO:0005886] activation of cysteine-type endopeptidase activity involved in apoptotic process [GO:0006919]; B cell receptor signaling pathway [GO:0050853]; cell differentiation [GO:0030154]; cellular zinc ion homeostasis [GO:0006882]; cytokine-mediated signaling pathway [GO:0019221]; hemopoiesis [GO:0030097]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; leukocyte migration [GO:0050900]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of heterotypic cell-cell adhesion [GO:0034116]; positive regulation of intrinsic apoptotic signaling pathway [GO:2001244]; positive regulation of leukocyte cell-cell adhesion [GO:1903039]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell receptor signaling pathway [GO:0050862]; protein phosphorylation [GO:0006468]; regulation of defense response to virus by virus [GO:0050690]; regulation of lymphocyte activation [GO:0051249]; release of sequestered calcium ion into cytosol [GO:0051209]; response to drug [GO:0042493]; T cell costimulation [GO:0031295]; T cell differentiation [GO:0030217]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169] ATPase binding [GO:0051117]; ATP binding [GO:0005524]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; identical protein binding [GO:0042802]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphatidylinositol 3-kinase binding [GO:0043548]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; phosphotyrosine residue binding [GO:0001784]; protein C-terminus binding [GO:0008022]; protein kinase binding [GO:0019901]; protein phosphatase binding [GO:0019903]; protein serine/threonine phosphatase activity [GO:0004722]; protein tyrosine kinase activity [GO:0004713]; SH2 domain binding [GO:0042169]; signaling receptor binding [GO:0005102]; T cell receptor binding [GO:0042608]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] GO:0000242; GO:0001772; GO:0001784; GO:0004713; GO:0004714; GO:0004715; GO:0004722; GO:0005102; GO:0005524; GO:0005829; GO:0005886; GO:0006468; GO:0006882; GO:0006919; GO:0007169; GO:0008022; GO:0016004; GO:0018108; GO:0019221; GO:0019901; GO:0019903; GO:0030097; GO:0030154; GO:0030168; GO:0030217; GO:0031234; GO:0031295; GO:0034116; GO:0035556; GO:0042169; GO:0042493; GO:0042608; GO:0042609; GO:0042610; GO:0042802; GO:0043274; GO:0043548; GO:0045087; GO:0045121; GO:0050690; GO:0050852; GO:0050853; GO:0050862; GO:0050870; GO:0050900; GO:0051117; GO:0051209; GO:0051249; GO:0051897; GO:0070062; GO:1903039; GO:2001244 PF07714;PF00017;PF00018; IPR011009;IPR035850;IPR035749;IPR000719;IPR017441;IPR001245;IPR000980;IPR036860;IPR036028;IPR001452;IPR008266;IPR020635; 4 O43149 Zinc finger ZZ-type and EF-hand domain-containing protein 1 Homo sapiens (Human) GNGSVKPK calcium ion binding [GO:0005509]; zinc ion binding [GO:0008270] GO:0005509; GO:0008270 PF03256;PF00569; IPR004939;IPR011992;IPR002048;IPR008979;IPR000433;IPR043145;IPR040099;IPR041986; 5 Q9NPB3 Calcium-binding protein 2 (CaBP2) Homo sapiens (Human) GNCCRSPA Golgi apparatus [GO:0005794]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] sensory perception of sound [GO:0007605]; signal transduction [GO:0007165]; visual perception [GO:0007601] calcium channel regulator activity [GO:0005246]; calcium ion binding [GO:0005509] GO:0005246; GO:0005509; GO:0005794; GO:0005886; GO:0007165; GO:0007601; GO:0007605; GO:0048471 PF00036;PF13499; IPR015754;IPR043582;IPR011992;IPR018247;IPR002048; 5 Q06850 Calcium-dependent protein kinase 1 (AtCDPK 1) (CDPK 1) (EC 2.7.11.1) (Calcium-dependent protein kinase isoform AK1) Arabidopsis thaliana (Mouse-ear cress) GNCLKSPT cytoplasm [GO:0005737]; nucleus [GO:0005634]; peroxisomal membrane [GO:0005778]; peroxisome [GO:0005777] intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of cell death [GO:0010941]; regulation of leaf senescence [GO:1900055] ATP binding [GO:0005524]; calcium-dependent protein kinase activity [GO:0010857]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0004672; GO:0004674; GO:0004683; GO:0005509; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005777; GO:0005778; GO:0006468; GO:0009931; GO:0010857; GO:0010941; GO:0018105; GO:0035556; GO:0046777; GO:0106310; GO:0106311; GO:1900055 PF13499;PF00069; IPR011992;IPR018247;IPR002048;IPR011009;IPR000719;IPR017441;IPR008271; 5 Q8W4I7 Calcium-dependent protein kinase 13 (EC 2.7.11.1) Arabidopsis thaliana (Mouse-ear cress) GNCAKRPW cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777] ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; protein serine/threonine kinase activity [GO:0004674]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0004674; GO:0004683; GO:0005509; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0009931; GO:0018105; GO:0035556; GO:0046777; GO:0106310; GO:0106311 PF13499;PF00069; IPR011992;IPR018247;IPR002048;IPR011009;IPR000719;IPR017441;IPR008271; 5 Q38870 Calcium-dependent protein kinase 2 (EC 2.7.11.1) (Calmodulin-domain protein kinase CDPK isoform 2) Arabidopsis thaliana (Mouse-ear cress) GNLLKVLT cytoplasm [GO:0005737]; endoplasmic reticulum membrane [GO:0005789]; nucleus [GO:0005634] intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777] ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0004683; GO:0005509; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005789; GO:0009931; GO:0018105; GO:0035556; GO:0046777; GO:0106310; GO:0106311 PF13499;PF00069; IPR011992;IPR018247;IPR002048;IPR011009;IPR000719;IPR017441;IPR008271; 5 Q9NUQ9 CYFIP-related Rac1 interactor B (L1) Homo sapiens (Human) GAHLVRRY cilium [GO:0005929]; extracellular exosome [GO:0070062]; extracellular region [GO:0005576]; membrane [GO:0016020]; mitochondrion [GO:0005739]; platelet alpha granule lumen [GO:0031093] cellular response to molecule of bacterial origin [GO:0071219]; negative regulation of actin filament polymerization [GO:0030837]; negative regulation of small GTPase mediated signal transduction [GO:0051058]; platelet degranulation [GO:0002576]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of memory T cell activation [GO:2000568]; positive regulation of T cell activation [GO:0050870]; positive regulation of T cell mediated cytotoxicity [GO:0001916]; regulation of cell migration [GO:0030334]; regulation of chemotaxis [GO:0050920]; regulation of establishment of cell polarity [GO:2000114]; regulation of mitochondrial fission [GO:0090140] MHC class Ib protein binding, via antigen binding groove [GO:0023030]; small GTPase binding [GO:0031267] GO:0001916; GO:0002576; GO:0005576; GO:0005739; GO:0005929; GO:0016020; GO:0023030; GO:0030334; GO:0030837; GO:0031093; GO:0031267; GO:0032729; GO:0050870; GO:0050920; GO:0051058; GO:0070062; GO:0071219; GO:0090140; GO:2000114; GO:2000568 PF07159; IPR039789;IPR009828; 5 P13200 Cytoplasmic envelopment protein 3 Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) GAHLARRY host cell Golgi membrane [GO:0044178]; host cell plasma membrane [GO:0020002]; viral tegument [GO:0019033]; virion membrane [GO:0055036] viral budding from Golgi membrane [GO:0046760] GO:0019033; GO:0020002; GO:0044178; GO:0046760; GO:0055036 IPR034705; 5 Q8IWE4 DCN1-like protein 3 (DCNL3) (DCUN1 domain-containing protein 3) (Defective in cullin neddylation protein 1-like protein 3) (Squamous cell carcinoma-related oncogene 3) Homo sapiens (Human) GLLCSRSR cytoplasm [GO:0005737]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; ubiquitin ligase complex [GO:0000151] negative regulation of cell growth [GO:0030308]; negative regulation of G1/S transition of mitotic cell cycle [GO:2000134]; negative regulation of protein neddylation [GO:2000435]; positive regulation of apoptotic process [GO:0043065]; positive regulation of protein neddylation [GO:2000436]; positive regulation of ubiquitin-protein transferase activity [GO:0051443]; post-translational protein modification [GO:0043687]; protein neddylation [GO:0045116]; regulation of cell cycle process [GO:0010564]; regulation of protein neddylation [GO:2000434]; response to gamma radiation [GO:0010332]; response to UV-C [GO:0010225] cullin family protein binding [GO:0097602]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin-like protein binding [GO:0032182] GO:0000151; GO:0005634; GO:0005737; GO:0005886; GO:0010225; GO:0010332; GO:0010564; GO:0030308; GO:0031624; GO:0032182; GO:0043065; GO:0043687; GO:0045116; GO:0048471; GO:0051443; GO:0097602; GO:2000134; GO:2000434; GO:2000435; GO:2000436 PF03556; IPR014764;IPR042460;IPR005176; 5 Q9C0E8 Endoplasmic reticulum junction formation protein lunapark (ER junction formation factor lunapark) Homo sapiens (Human) GGLFSRWR endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; endoplasmic reticulum tubular network [GO:0071782]; endoplasmic reticulum tubular network membrane [GO:0098826]; integral component of endoplasmic reticulum membrane [GO:0030176]; integral component of membrane [GO:0016021]; nucleoplasm [GO:0005654] blood coagulation [GO:0007596]; embryonic digit morphogenesis [GO:0042733]; embryonic forelimb morphogenesis [GO:0035115]; endoplasmic reticulum organization [GO:0007029]; endoplasmic reticulum tubular network maintenance [GO:0071788]; endoplasmic reticulum tubular network organization [GO:0071786]; limb development [GO:0060173]; positive regulation of endoplasmic reticulum tubular network organization [GO:1903373]; regulation of chondrocyte differentiation [GO:0032330] identical protein binding [GO:0042802]; metal ion binding [GO:0046872] GO:0005654; GO:0005783; GO:0005789; GO:0007029; GO:0007596; GO:0016021; GO:0030176; GO:0032330; GO:0035115; GO:0042733; GO:0042802; GO:0046872; GO:0060173; GO:0071782; GO:0071786; GO:0071788; GO:0098826; GO:1903373 PF10058; IPR040115;IPR019273; 5 P18064 Guanine nucleotide-binding protein alpha-1 subunit (GP-alpha-1) Arabidopsis thaliana (Mouse-ear cress) GSTDSKLN endoplasmic reticulum membrane [GO:0005789]; heterotrimeric G-protein complex [GO:0005834]; peroxisome [GO:0005777]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506] abscisic acid-activated signaling pathway [GO:0009738]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; blue light signaling pathway [GO:0009785]; cell death [GO:0008219]; gibberellic acid mediated signaling pathway [GO:0009740]; G protein-coupled receptor signaling pathway [GO:0007186]; L-phenylalanine biosynthetic process [GO:0009094]; positive regulation of abscisic acid-activated signaling pathway [GO:0009789]; reactive oxygen species metabolic process [GO:0072593]; regulation of cell population proliferation [GO:0042127]; regulation of stomatal closure [GO:0090333]; regulation of stomatal movement [GO:0010119]; response to glucose [GO:0009749]; response to low fluence blue light stimulus by blue low-fluence system [GO:0010244]; response to pheromone [GO:0019236]; seed germination [GO:0009845]; sphingosine-1-phosphate receptor signaling pathway [GO:0003376]; thylakoid membrane organization [GO:0010027]; tyrosine biosynthetic process [GO:0006571] channel regulator activity [GO:0016247]; G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; GTPase activity [GO:0003924]; GTPase binding [GO:0051020]; GTPase inhibitor activity [GO:0005095]; GTP binding [GO:0005525]; metal ion binding [GO:0046872] GO:0001664; GO:0003376; GO:0003924; GO:0005095; GO:0005525; GO:0005777; GO:0005789; GO:0005834; GO:0005886; GO:0006571; GO:0007186; GO:0007188; GO:0008219; GO:0009094; GO:0009506; GO:0009738; GO:0009740; GO:0009749; GO:0009785; GO:0009789; GO:0009845; GO:0010027; GO:0010119; GO:0010244; GO:0016247; GO:0019236; GO:0031683; GO:0042127; GO:0046872; GO:0051020; GO:0072593; GO:0090333 PF00503; IPR001019;IPR011025;IPR027417;IPR002976; 5 P63252 Inward rectifier potassium channel 2 (Cardiac inward rectifier potassium channel) (Inward rectifier K(+) channel Kir2.1) (IRK-1) (hIRK1) (Potassium channel, inwardly rectifying subfamily J member 2) Homo sapiens (Human) GAYLSQPN dendritic spine [GO:0043197]; Golgi apparatus [GO:0005794]; integral component of plasma membrane [GO:0005887]; intercalated disc [GO:0014704]; intrinsic component of membrane [GO:0031224]; neuronal cell body [GO:0043025]; plasma membrane [GO:0005886]; rough endoplasmic reticulum [GO:0005791]; smooth endoplasmic reticulum [GO:0005790]; T-tubule [GO:0030315]; voltage-gated potassium channel complex [GO:0008076] cardiac conduction [GO:0061337]; cardiac muscle cell action potential involved in contraction [GO:0086002]; cellular potassium ion homeostasis [GO:0030007]; cellular response to mechanical stimulus [GO:0071260]; magnesium ion transport [GO:0015693]; membrane depolarization during cardiac muscle cell action potential [GO:0086012]; membrane repolarization during action potential [GO:0086011]; membrane repolarization during cardiac muscle cell action potential [GO:0086013]; positive regulation of potassium ion transmembrane transport [GO:1901381]; potassium ion import across plasma membrane [GO:1990573]; potassium ion transmembrane transport [GO:0071805]; potassium ion transport [GO:0006813]; protein homotetramerization [GO:0051289]; regulation of cardiac muscle cell contraction [GO:0086004]; regulation of heart rate by cardiac conduction [GO:0086091]; regulation of ion transmembrane transport [GO:0034765]; regulation of membrane repolarization [GO:0060306]; regulation of resting membrane potential [GO:0060075]; regulation of skeletal muscle contraction via regulation of action potential [GO:0014861]; relaxation of cardiac muscle [GO:0055119]; relaxation of skeletal muscle [GO:0090076] identical protein binding [GO:0042802]; inward rectifier potassium channel activity [GO:0005242]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546]; voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization [GO:0086008] GO:0005242; GO:0005546; GO:0005790; GO:0005791; GO:0005794; GO:0005886; GO:0005887; GO:0006813; GO:0008076; GO:0014704; GO:0014861; GO:0015693; GO:0030007; GO:0030315; GO:0031224; GO:0034765; GO:0042802; GO:0043025; GO:0043197; GO:0051289; GO:0055119; GO:0060075; GO:0060306; GO:0061337; GO:0071260; GO:0071805; GO:0086002; GO:0086004; GO:0086008; GO:0086011; GO:0086012; GO:0086013; GO:0086091; GO:0090076; GO:1901381; GO:1990573 PF01007;PF17655;PF08466; IPR014756;IPR041647;IPR016449;IPR003271;IPR013518;IPR013673;IPR040445; 5 P17568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (Cell adhesion protein SQM1) (Complex I-B18) (CI-B18) (NADH-ubiquinone oxidoreductase B18 subunit) Homo sapiens (Human) GSVRTNRY mitochondrial inner membrane [GO:0005743]; mitochondrial intermembrane space [GO:0005758]; mitochondrial respiratory chain complex I [GO:0005747]; mitochondrion [GO:0005739] mitochondrial electron transport, NADH to ubiquinone [GO:0006120]; mitochondrial respiratory chain complex I assembly [GO:0032981] NADH dehydrogenase (ubiquinone) activity [GO:0008137] GO:0005739; GO:0005743; GO:0005747; GO:0005758; GO:0006120; GO:0008137; GO:0032981 PF05676; IPR008698; 5 Q02368 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (Complex I-B18) (CI-B18) (NADH-ubiquinone oxidoreductase B18 subunit) Bos taurus (Bovine) GNTCVGPS mitochondrial intermembrane space [GO:0005758]; mitochondrial respiratory chain complex I [GO:0005747] mitochondrial respiratory chain complex I assembly [GO:0032981] NADH dehydrogenase (ubiquinone) activity [GO:0008137] GO:0005747; GO:0005758; GO:0008137; GO:0032981 PF05676; IPR008698; 5 Q96262 Plasma membrane-associated cation-binding protein 1 (AtPCAP1) (Microtubule-destabilizing protein 25) Arabidopsis thaliana (Mouse-ear cress) GNACVGPN anchored component of plasma membrane [GO:0046658]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; host cell [GO:0043657]; plasma membrane [GO:0005886]; plasmodesma [GO:0009506]; vacuole [GO:0005773] cellular response to copper ion [GO:0071280]; cellular response to iron ion [GO:0071281]; cellular response to magnesium ion [GO:0071286]; cellular response to magnesium starvation [GO:0010350]; cellular response to mannitol stimulus [GO:0071325]; cellular response to molecule of bacterial origin [GO:0071219]; cellular response to potassium ion [GO:0035865]; cellular response to salt stress [GO:0071472]; cellular response to sorbitol [GO:0072709]; cortical microtubule organization [GO:0043622]; defense response to bacterium [GO:0042742]; intracellular transport of virus [GO:0075733]; negative regulation of microtubule polymerization [GO:0031115]; negative regulation of unidimensional cell growth [GO:0051511]; N-terminal protein myristoylation [GO:0006499]; positive regulation of microtubule depolymerization [GO:0031117]; response to calcium ion [GO:0051592]; response to cold [GO:0009409]; response to water deprivation [GO:0009414]; stomatal closure [GO:0090332] calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; copper ion binding [GO:0005507]; microtubule binding [GO:0008017]; phosphatidylinositol-3,4,5-trisphosphate binding [GO:0005547]; phosphatidylinositol-3,4-bisphosphate binding [GO:0043325]; phosphatidylinositol-3,5-bisphosphate binding [GO:0080025]; phosphatidylinositol-4,5-bisphosphate binding [GO:0005546] GO:0005507; GO:0005509; GO:0005516; GO:0005546; GO:0005547; GO:0005773; GO:0005829; GO:0005881; GO:0005886; GO:0006499; GO:0008017; GO:0009409; GO:0009414; GO:0009506; GO:0010350; GO:0031115; GO:0031117; GO:0035865; GO:0042742; GO:0043325; GO:0043622; GO:0043657; GO:0046658; GO:0051511; GO:0051592; GO:0071219; GO:0071280; GO:0071281; GO:0071286; GO:0071325; GO:0071472; GO:0072709; GO:0075733; GO:0080025; GO:0090332 PF05558; IPR008469; 5 Q9LU05 Plasma membrane-associated cation-binding protein 2 (AtPCAP2) (Lysine rich protein At168) (Microtubule-associated protein 18) Arabidopsis thaliana (Mouse-ear cress) GQCVTKCK anchored component of plasma membrane [GO:0046658]; cytoplasm [GO:0005737]; microtubule [GO:0005874]; plasma membrane [GO:0005886]; pollen tube [GO:0090406] cell morphogenesis [GO:0000902]; cortical microtubule organization [GO:0043622]; leaf senescence [GO:0010150]; negative regulation of microtubule polymerization [GO:0031115]; regulation of cell shape [GO:0008360]; response to abscisic acid [GO:0009737]; response to arsenic-containing substance [GO:0046685]; response to cold [GO:0009409]; response to gibberellin [GO:0009739]; response to metal ion [GO:0010038]; response to salt stress [GO:0009651]; root hair cell tip growth [GO:0048768]; signal transduction [GO:0007165] 1-phosphatidylinositol binding [GO:0005545]; calmodulin binding [GO:0005516]; microtubule binding [GO:0008017]; phosphatidylinositol phosphate binding [GO:1901981]; signaling receptor activity [GO:0038023] GO:0000902; GO:0005516; GO:0005545; GO:0005737; GO:0005874; GO:0005886; GO:0007165; GO:0008017; GO:0008360; GO:0009409; GO:0009651; GO:0009737; GO:0009739; GO:0010038; GO:0010150; GO:0031115; GO:0038023; GO:0043622; GO:0046658; GO:0046685; GO:0048768; GO:0090406; GO:1901981 PF05558; IPR008469; 5 P26313 Pre-glycoprotein polyprotein GP complex (Pre-GP-C) [Cleaved into: Stable signal peptide (SSP); Glycoprotein G1 (GP1); Glycoprotein G2 (GP2)] Junin mammarenavirus (JUNV) (Junn mammarenavirus) GQFISFMQ host cell endoplasmic reticulum membrane [GO:0044167]; host cell Golgi membrane [GO:0044178]; host cell plasma membrane [GO:0020002]; integral component of membrane [GO:0016021]; viral envelope [GO:0019031]; virion membrane [GO:0055036] fusion of virus membrane with host endosome membrane [GO:0039654]; receptor-mediated endocytosis of virus by host cell [GO:0019065]; virion attachment to host cell [GO:0019062] metal ion binding [GO:0046872] GO:0016021; GO:0019031; GO:0019062; GO:0019065; GO:0020002; GO:0039654; GO:0044167; GO:0044178; GO:0046872; GO:0055036 PF00798; IPR001535;IPR043015; 5 Q8IV36 Protein HID1 (Down-regulated in multiple cancers 1) (HID1 domain-containing protein) (Protein hid-1 homolog) Homo sapiens (Human) GYWKSKVV cytoplasm [GO:0005737]; cytoplasmic microtubule [GO:0005881]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; extrinsic component of Golgi membrane [GO:0090498]; Golgi apparatus [GO:0005794]; Golgi medial cisterna [GO:0005797]; Golgi trans cisterna [GO:0000138]; membrane [GO:0016020] GO:0000138; GO:0005737; GO:0005794; GO:0005797; GO:0005829; GO:0005881; GO:0016020; GO:0070062; GO:0090498 PF12722; IPR026705; 5 O15355 Protein phosphatase 1G (EC 3.1.3.16) (Protein phosphatase 1C) (Protein phosphatase 2C isoform gamma) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma) Homo sapiens (Human) GYWNSKVV cytoplasm [GO:0005737]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] cell cycle arrest [GO:0007050]; peptidyl-threonine dephosphorylation [GO:0035970]; protein dephosphorylation [GO:0006470] metal ion binding [GO:0046872]; protein serine/threonine phosphatase activity [GO:0004722]; protein serine phosphatase activity [GO:0106306]; protein threonine phosphatase activity [GO:0106307] GO:0004722; GO:0005634; GO:0005654; GO:0005737; GO:0006470; GO:0007050; GO:0016020; GO:0035970; GO:0046872; GO:0106306; GO:0106307 PF00481; IPR015655;IPR000222;IPR036457;IPR001932; 5 Q9Y3C5 RING finger protein 11 Homo sapiens (Human) GQKSSKVH early endosome [GO:0005769]; extracellular exosome [GO:0070062]; nucleus [GO:0005634]; recycling endosome [GO:0055037]; ubiquitin ligase complex [GO:0000151] protein autoubiquitination [GO:0051865]; ubiquitin-dependent protein catabolic process [GO:0006511] DNA binding [GO:0003677]; ubiquitin protein ligase activity [GO:0061630]; zinc ion binding [GO:0008270] GO:0000151; GO:0003677; GO:0005634; GO:0005769; GO:0006511; GO:0008270; GO:0051865; GO:0055037; GO:0061630; GO:0070062 PF13639; IPR042981;IPR001841;IPR013083; 5 Q04272 Vacuolar protein sorting-associated protein 20 (Amino acid sensor-independent protein 10) (Charged multivesicular body protein 6) (ESCRT-III complex subunit VPS20) (Vacuolar protein-targeting protein 20) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) GAELCKRI cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; ESCRT III complex [GO:0000815]; multivesicular body [GO:0005771]; vacuolar membrane [GO:0005774] ATP export [GO:1904669]; intralumenal vesicle formation [GO:0070676]; late endosome to vacuole transport [GO:0045324]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; protein transport [GO:0015031]; ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [GO:0043162]; vesicle budding from membrane [GO:0006900] GO:0000815; GO:0005737; GO:0005771; GO:0005774; GO:0005783; GO:0005829; GO:0006900; GO:0015031; GO:0032511; GO:0043162; GO:0045324; GO:0070676; GO:1904669 PF03357; IPR005024; 6 P62241 40S ribosomal protein S8 (Small ribosomal subunit protein eS8) Homo sapiens (Human) GNRHAKAS cytosol [GO:0005829]; cytosolic ribosome [GO:0022626]; cytosolic small ribosomal subunit [GO:0022627]; endoplasmic reticulum [GO:0005783]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; ribonucleoprotein complex [GO:1990904] cytoplasmic translation [GO:0002181]; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [GO:0000462]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; translation [GO:0006412]; translational initiation [GO:0006413]; viral transcription [GO:0019083] RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] GO:0000184; GO:0000462; GO:0002181; GO:0003723; GO:0003735; GO:0005634; GO:0005654; GO:0005783; GO:0005829; GO:0005925; GO:0006412; GO:0006413; GO:0006614; GO:0016020; GO:0019083; GO:0022626; GO:0022627; GO:0070062; GO:1990904 PF01201; IPR042563;IPR001047;IPR022309;IPR018283; 6 O43687 A-kinase anchor protein 7 isoforms alpha and beta (AKAP-7 isoforms alpha and beta) (A-kinase anchor protein 18 kDa) (AKAP 18) (Protein kinase A-anchoring protein 7 isoforms alpha/beta) (PRKA7 isoforms alpha/beta) Homo sapiens (Human) GNSALRAH apical plasma membrane [GO:0016324]; lateral plasma membrane [GO:0016328]; plasma membrane [GO:0005886] action potential [GO:0001508]; cellular response to cAMP [GO:0071320]; intracellular signal transduction [GO:0035556]; ion transport [GO:0006811]; positive regulation of delayed rectifier potassium channel activity [GO:1902261]; positive regulation of potassium ion transmembrane transport [GO:1901381]; protein localization [GO:0008104]; regulation of membrane repolarization [GO:0060306] protein kinase A binding [GO:0051018] GO:0001508; GO:0005886; GO:0006811; GO:0008104; GO:0016324; GO:0016328; GO:0035556; GO:0051018; GO:0060306; GO:0071320; GO:1901381; GO:1902261 PF10470; IPR019511; 6 P27216 Annexin A13 (Annexin XIII) (Annexin-13) (Intestine-specific annexin) (ISA) Homo sapiens (Human) GNKQAKAP apical plasma membrane [GO:0016324]; basolateral plasma membrane [GO:0016323]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; exocytic vesicle [GO:0070382]; extracellular exosome [GO:0070062]; extracellular space [GO:0005615]; extrinsic component of membrane [GO:0019898]; membrane raft [GO:0045121]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] cell differentiation [GO:0030154]; negative regulation of Golgi to plasma membrane protein transport [GO:0042997]; positive regulation of Golgi to plasma membrane protein transport [GO:0042998] calcium-dependent phospholipid binding [GO:0005544]; calcium ion binding [GO:0005509]; phosphatidylglycerol binding [GO:1901611]; phosphatidylserine binding [GO:0001786] GO:0001786; GO:0005509; GO:0005544; GO:0005615; GO:0005654; GO:0005737; GO:0005886; GO:0016323; GO:0016324; GO:0019898; GO:0030154; GO:0031410; GO:0042997; GO:0042998; GO:0045121; GO:0070062; GO:0070382; GO:1901611 PF00191; IPR001464;IPR018502;IPR018252;IPR037104;IPR009166; 6 Q38868 Calcium-dependent protein kinase 9 (EC 2.7.11.1) (Calmodulin-domain protein kinase CDPK isoform 9) Arabidopsis thaliana (Mouse-ear cress) GNRAFKAH cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; plasma membrane [GO:0005886] intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; signal transduction [GO:0007165] ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0004683; GO:0005509; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0007165; GO:0009931; GO:0018105; GO:0035556; GO:0046777; GO:0106310; GO:0106311 PF13499;PF00069; IPR011992;IPR018247;IPR002048;IPR011009;IPR000719;IPR017441;IPR008271; 6 Q9SG12 CDPK-related kinase 6 (AtCRK6) (EC 2.7.11.1) (Calcium/calmodulin-dependent protein kinase CRK6) Arabidopsis thaliana (Mouse-ear cress) GNRAFKSH cytoplasm [GO:0005737]; nucleus [GO:0005634]; plasma membrane [GO:0005886] intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777] ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; metal ion binding [GO:0046872]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0004683; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005886; GO:0009931; GO:0018105; GO:0035556; GO:0046777; GO:0046872; GO:0106310; GO:0106311 PF00069; IPR011992;IPR011009;IPR000719;IPR017441;IPR008271; 6 Q14254 Flotillin-2 (Epidermal surface antigen) (ESA) (Membrane component chromosome 17 surface marker 1) Homo sapiens (Human) GNSAARSD adherens junction [GO:0005912]; basolateral plasma membrane [GO:0016323]; caveola [GO:0005901]; cell-cell contact zone [GO:0044291]; cytoplasmic vesicle [GO:0031410]; endocytic vesicle [GO:0030139]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; flotillin complex [GO:0016600]; focal adhesion [GO:0005925]; intracellular membrane-bounded organelle [GO:0043231]; lamellipodium [GO:0030027]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; uropod [GO:0001931]; vesicle [GO:0031982] cell adhesion [GO:0007155]; epidermis development [GO:0008544]; membrane raft assembly [GO:0001765]; negative regulation of amyloid precursor protein catabolic process [GO:1902992]; negative regulation of gene expression [GO:0010629]; positive regulation of establishment of T cell polarity [GO:1903905]; positive regulation of NF-kappaB transcription factor activity [GO:0051092]; protein localization to plasma membrane [GO:0072659]; protein localization to plasma membrane raft [GO:0044860]; protein stabilization [GO:0050821]; regulation of myoblast differentiation [GO:0045661]; regulation of necroptotic process [GO:0060544] GO:0001765; GO:0001931; GO:0005768; GO:0005886; GO:0005901; GO:0005912; GO:0005925; GO:0007155; GO:0008544; GO:0010629; GO:0016020; GO:0016323; GO:0016600; GO:0030027; GO:0030139; GO:0031410; GO:0031982; GO:0043231; GO:0044291; GO:0044860; GO:0045661; GO:0048471; GO:0050821; GO:0051092; GO:0060544; GO:0070062; GO:0072659; GO:1902992; GO:1903905 PF01145;PF15975; IPR001107;IPR036013;IPR031905;IPR027705; 6 P03355 Gag-Pol polyprotein (Pr180gag-pol) [Cleaved into: Matrix protein p15 (MA); RNA-binding phosphoprotein p12 (pp12); Capsid protein p30 (CA); Nucleocapsid protein p10-Pol (NC-pol); Protease (PR) (EC 3.4.23.-) (p14); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4) (p80); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-) (p46)] Moloney murine leukemia virus (isolate Shinnick) (MoMLV) GISRDNWH host cell late endosome membrane [GO:0044185]; host cell plasma membrane [GO:0020002]; host multivesicular body [GO:0072494]; membrane [GO:0016020]; protein-DNA complex [GO:0032993]; viral nucleocapsid [GO:0019013] DNA catabolic process [GO:0006308]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826]; viral translational readthrough [GO:0039705]; virion assembly [GO:0019068] aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; retroviral 3' processing activity [GO:0044824]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural constituent of virion [GO:0039660]; zinc ion binding [GO:0008270] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0006308; GO:0006310; GO:0008270; GO:0016020; GO:0019013; GO:0019068; GO:0020002; GO:0032993; GO:0039657; GO:0039660; GO:0039705; GO:0044185; GO:0044824; GO:0044826; GO:0046718; GO:0072494; GO:0075713 PF01140;PF01141;PF02093;PF18697;PF00075;PF17919;PF00665;PF00077;PF00078;PF00098;PF16721; IPR001969;IPR043502;IPR000840;IPR036946;IPR039464;IPR002079;IPR003036;IPR001584;IPR040643;IPR001995;IPR021109;IPR018061;IPR008919;IPR010999;IPR043128;IPR012337;IPR002156;IPR036397;IPR000477;IPR041577;IPR001878;IPR036875; 6 P38405 Guanine nucleotide-binding protein G(olf) subunit alpha (Adenylate cyclase-stimulating G alpha protein, olfactory type) Homo sapiens (Human) GNCHTVGP extracellular exosome [GO:0070062]; heterotrimeric G-protein complex [GO:0005834]; plasma membrane [GO:0005886] adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; sensory perception of chemical stimulus [GO:0007606]; signal transduction [GO:0007165] G-protein beta/gamma-subunit complex binding [GO:0031683]; G protein-coupled receptor binding [GO:0001664]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872] GO:0001664; GO:0003924; GO:0005525; GO:0005834; GO:0005886; GO:0007165; GO:0007188; GO:0007189; GO:0007191; GO:0007193; GO:0007606; GO:0031683; GO:0046872; GO:0070062 PF00503; IPR000367;IPR001019;IPR011025;IPR027417; 6 P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Adenylate cyclase-stimulating G alpha protein) Homo sapiens (Human) GQTVTTPL cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; heterotrimeric G-protein complex [GO:0005834]; intrinsic component of membrane [GO:0031224]; membrane [GO:0016020]; plasma membrane [GO:0005886]; trans-Golgi network membrane [GO:0032588] activation of adenylate cyclase activity [GO:0007190]; adenylate cyclase-activating adrenergic receptor signaling pathway [GO:0071880]; adenylate cyclase-activating dopamine receptor signaling pathway [GO:0007191]; adenylate cyclase-activating G protein-coupled receptor signaling pathway [GO:0007189]; bone development [GO:0060348]; cellular response to catecholamine stimulus [GO:0071870]; cellular response to glucagon stimulus [GO:0071377]; cellular response to prostaglandin E stimulus [GO:0071380]; cognition [GO:0050890]; developmental growth [GO:0048589]; G protein-coupled receptor signaling pathway [GO:0007186]; hair follicle placode formation [GO:0060789]; intracellular transport [GO:0046907]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; platelet aggregation [GO:0070527]; positive regulation of cAMP-mediated signaling [GO:0043950]; positive regulation of cold-induced thermogenesis [GO:0120162]; positive regulation of GTPase activity [GO:0043547]; regulation of insulin secretion [GO:0050796]; renal water homeostasis [GO:0003091]; sensory perception of smell [GO:0007608] adenylate cyclase activator activity [GO:0010856]; G-protein beta/gamma-subunit complex binding [GO:0031683]; GTPase activity [GO:0003924]; GTP binding [GO:0005525]; metal ion binding [GO:0046872] GO:0002862; GO:0003091; GO:0003924; GO:0005525; GO:0005737; GO:0005829; GO:0005834; GO:0005886; GO:0007186; GO:0007189; GO:0007190; GO:0007191; GO:0007608; GO:0010856; GO:0016020; GO:0031224; GO:0031683; GO:0032588; GO:0043547; GO:0043950; GO:0046872; GO:0046907; GO:0048589; GO:0050796; GO:0050890; GO:0060348; GO:0060789; GO:0070062; GO:0070527; GO:0071377; GO:0071380; GO:0071870; GO:0071880; GO:0120162 PF00503; IPR000367;IPR001019;IPR011025;IPR027417; 6 P13231 Hisactophilin-1 (Histidine-rich actin-binding protein 1) (HS I) Dictyostelium discoideum (Slime mold) GHCYSRNI actin cytoskeleton [GO:0015629]; cytosol [GO:0005829]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886] actin filament polymerization [GO:0030041] actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; fatty acid binding [GO:0005504]; lipid binding [GO:0008289]; protein-macromolecule adaptor activity [GO:0030674] GO:0003785; GO:0005504; GO:0005829; GO:0005886; GO:0008289; GO:0015629; GO:0030041; GO:0030674; GO:0045335; GO:0051015 PF06268; IPR008999;IPR022768; 6 P42526 Hisactophilin-2 (Histidine-rich actin-binding protein 2) (HS II) Dictyostelium discoideum (Slime mold) GNSRSRVG cytosol [GO:0005829]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886] response to acidic pH [GO:0010447] actin filament binding [GO:0051015]; fatty acid binding [GO:0005504]; lipid binding [GO:0008289]; protein-macromolecule adaptor activity [GO:0030674] GO:0005504; GO:0005829; GO:0005886; GO:0008289; GO:0010447; GO:0030674; GO:0045335; GO:0051015 PF06268; IPR008999;IPR022768; 6 Q8N9N7 Leucine-rich repeat-containing protein 57 Homo sapiens (Human) GCLGGNSK extracellular exosome [GO:0070062]; membrane [GO:0016020] GO:0016020; GO:0070062 PF00560;PF13855; IPR001611;IPR003591;IPR032675; 6 Q6P9B6 MTOR-associated protein MEAK7 (MEAK7) (MTOR associated protein, eak-7 homolog) (TBC/LysM-associated domain-containing protein 1) (TLD domain-containing protein 1) Homo sapiens (Human) GNCFAKNH cytoplasm [GO:0005737]; cytosol [GO:0005829]; lysosomal membrane [GO:0005765]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654] negative regulation of oxidative stress-induced neuron death [GO:1903204]; positive regulation of protein localization to lysosome [GO:0150032]; regulation of cell migration [GO:0030334]; regulation of cell population proliferation [GO:0042127]; response to amino acid [GO:0043200]; response to insulin [GO:0032868]; response to nutrient levels [GO:0031667]; TOR signaling [GO:0031929] GO:0005654; GO:0005730; GO:0005737; GO:0005765; GO:0005829; GO:0016020; GO:0030334; GO:0031667; GO:0031929; GO:0032868; GO:0042127; GO:0043200; GO:0150032; GO:1903204 PF07534; IPR006571; 6 Q14699 Raftlin (Cell migration-inducing gene 2 protein) (Raft-linking protein) Homo sapiens (Human) GCVQCKDK cytoplasm [GO:0005737]; early endosome [GO:0005769]; endosome [GO:0005768]; extracellular exosome [GO:0070062]; membrane raft [GO:0045121]; plasma membrane [GO:0005886]; protein-containing complex [GO:0032991] B cell receptor signaling pathway [GO:0050853]; dsRNA transport [GO:0033227]; membrane raft assembly [GO:0001765]; positive regulation of growth rate [GO:0040010]; positive regulation of interleukin-17 production [GO:0032740]; protein localization to membrane raft [GO:1903044]; protein transport into membrane raft [GO:0032596]; response to exogenous dsRNA [GO:0043330]; T cell antigen processing and presentation [GO:0002457]; T cell receptor signaling pathway [GO:0050852]; toll-like receptor 3 signaling pathway [GO:0034138] double-stranded RNA binding [GO:0003725] GO:0001765; GO:0002457; GO:0003725; GO:0005737; GO:0005768; GO:0005769; GO:0005886; GO:0032596; GO:0032740; GO:0032991; GO:0033227; GO:0034138; GO:0040010; GO:0043330; GO:0045121; GO:0050852; GO:0050853; GO:0070062; GO:1903044 PF15250; IPR028169; 6 O73557 RING finger protein Z (Protein Z) (Zinc-binding protein) Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) (LASV) GGSHSQTP host cell perinuclear region of cytoplasm [GO:0044220]; host cell plasma membrane [GO:0020002]; membrane [GO:0016020]; virion [GO:0019012] viral budding from plasma membrane [GO:0046761]; viral budding via host ESCRT complex [GO:0039702] RNA binding [GO:0003723]; zinc ion binding [GO:0008270] GO:0003723; GO:0008270; GO:0016020; GO:0019012; GO:0020002; GO:0039702; GO:0044220; GO:0046761 PF03854; IPR024183;IPR038485;IPR003224; 6 Q8NHG7 Small VCP/p97-interacting protein Homo sapiens (Human) GCGLNKLE anchored component of membrane [GO:0031225]; endoplasmic reticulum membrane [GO:0005789]; extracellular exosome [GO:0070062]; Golgi membrane [GO:0000139]; plasma membrane [GO:0005886]; secretory granule membrane [GO:0030667]; smooth endoplasmic reticulum membrane [GO:0030868]; tertiary granule membrane [GO:0070821] negative regulation of ER-associated ubiquitin-dependent protein catabolic process [GO:1903070]; negative regulation of protein-containing complex assembly [GO:0031333]; negative regulation of retrograde protein transport, ER to cytosol [GO:1904153]; negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly [GO:1904240]; neutrophil degranulation [GO:0043312]; positive regulation of autophagy [GO:0010508]; positive regulation of protein lipidation [GO:1903061] ATPase binding [GO:0051117]; protein self-association [GO:0043621] GO:0000139; GO:0005789; GO:0005886; GO:0010508; GO:0030667; GO:0030868; GO:0031225; GO:0031333; GO:0043312; GO:0043621; GO:0051117; GO:0070062; GO:0070821; GO:1903061; GO:1903070; GO:1904153; GO:1904240 PF15811; IPR031632; 6 Q564G3 Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2 (EC 1.14.18.5) (EC 1.14.19.17) (Degenerative spermatocyte homolog 2) (Sphingolipid 4-desaturase) (Sphingolipid C4-monooxygenase) Rattus norvegicus (Rat) GCLGNSKT endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021] ceramide biosynthetic process [GO:0046513]; sphinganine metabolic process [GO:0006667]; sphingolipid biosynthetic process [GO:0030148] sphingolipid delta-4 desaturase activity [GO:0042284]; sphingosine hydroxylase activity [GO:0000170] GO:0000170; GO:0005789; GO:0006667; GO:0016021; GO:0030148; GO:0042284; GO:0046513 PF00487;PF08557; IPR011388;IPR005804;IPR013866; 6 O75410 Transforming acidic coiled-coil-containing protein 1 (Gastric cancer antigen Ga55) (Taxin-1) Homo sapiens (Human) GLCFPCPG cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; midbody [GO:0030496]; nucleus [GO:0005634] cell division [GO:0051301]; cell population proliferation [GO:0008283]; cerebral cortex development [GO:0021987]; microtubule cytoskeleton organization [GO:0000226]; mitotic spindle organization [GO:0007052] estrogen receptor binding [GO:0030331]; glucocorticoid receptor binding [GO:0035259]; nuclear receptor binding [GO:0016922]; nuclear receptor coactivator activity [GO:0030374]; peroxisome proliferator activated receptor binding [GO:0042975]; retinoic acid receptor binding [GO:0042974]; retinoid X receptor binding [GO:0046965]; thyroid hormone receptor binding [GO:0046966] GO:0000226; GO:0005634; GO:0005737; GO:0005815; GO:0005829; GO:0007052; GO:0008283; GO:0016020; GO:0016922; GO:0021987; GO:0030331; GO:0030374; GO:0030496; GO:0035259; GO:0042974; GO:0042975; GO:0046965; GO:0046966; GO:0051301 PF05010; IPR039915;IPR007707; 6 P06241 Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene Syn) (Proto-oncogene c-Fyn) (Src-like kinase) (SLK) (p59-Fyn) Homo sapiens (Human) GQLCCFPF actin filament [GO:0005884]; cell body [GO:0044297]; cytosol [GO:0005829]; dendrite [GO:0030425]; endosome [GO:0005768]; extrinsic component of cytoplasmic side of plasma membrane [GO:0031234]; glial cell projection [GO:0097386]; glutamatergic synapse [GO:0098978]; membrane raft [GO:0045121]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; perinuclear endoplasmic reticulum [GO:0097038]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069]; postsynaptic density, intracellular component [GO:0099092]; Schaffer collateral - CA1 synapse [GO:0098685] activated T cell proliferation [GO:0050798]; adaptive immune response [GO:0002250]; axon guidance [GO:0007411]; blood coagulation [GO:0007596]; calcium ion transport [GO:0006816]; cell differentiation [GO:0030154]; cellular response to amyloid-beta [GO:1904646]; cellular response to glycine [GO:1905430]; cellular response to L-glutamate [GO:1905232]; cellular response to peptide hormone stimulus [GO:0071375]; cellular response to platelet-derived growth factor stimulus [GO:0036120]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cytokine-mediated signaling pathway [GO:0019221]; dendrite morphogenesis [GO:0048813]; dendritic spine maintenance [GO:0097062]; detection of mechanical stimulus involved in sensory perception of pain [GO:0050966]; ephrin receptor signaling pathway [GO:0048013]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; feeding behavior [GO:0007631]; forebrain development [GO:0030900]; heart process [GO:0003015]; innate immune response [GO:0045087]; intracellular signal transduction [GO:0035556]; learning [GO:0007612]; leukocyte migration [GO:0050900]; MAPK cascade [GO:0000165]; modulation of chemical synaptic transmission [GO:0050804]; negative regulation of dendritic spine maintenance [GO:1902951]; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [GO:2001240]; negative regulation of gene expression [GO:0010629]; negative regulation of hydrogen peroxide biosynthetic process [GO:0010730]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of neuron apoptotic process [GO:0043524]; negative regulation of oxidative stress-induced cell death [GO:1903202]; negative regulation of protein catabolic process [GO:0042177]; negative regulation of protein ubiquitination [GO:0031397]; neuron migration [GO:0001764]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet activation [GO:0030168]; positive regulation of cysteine-type endopeptidase activity [GO:2001056]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of neuron death [GO:1901216]; positive regulation of neuron projection development [GO:0010976]; positive regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903997]; positive regulation of phosphatidylinositol 3-kinase signaling [GO:0014068]; positive regulation of protein kinase B signaling [GO:0051897]; positive regulation of protein localization to membrane [GO:1905477]; positive regulation of protein localization to nucleus [GO:1900182]; positive regulation of protein targeting to membrane [GO:0090314]; positive regulation of tyrosine phosphorylation of STAT protein [GO:0042531]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of calcium ion import across plasma membrane [GO:1905664]; regulation of cell shape [GO:0008360]; regulation of defense response to virus by virus [GO:0050690]; regulation of glutamate receptor signaling pathway [GO:1900449]; regulation of peptidyl-tyrosine phosphorylation [GO:0050730]; response to amyloid-beta [GO:1904645]; response to drug [GO:0042493]; response to ethanol [GO:0045471]; response to hydrogen peroxide [GO:0042542]; response to singlet oxygen [GO:0000304]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell costimulation [GO:0031295]; T cell receptor signaling pathway [GO:0050852]; transmembrane receptor protein tyrosine kinase signaling pathway [GO:0007169]; vascular endothelial growth factor receptor signaling pathway [GO:0048010] alpha-tubulin binding [GO:0043014]; ATP binding [GO:0005524]; CD4 receptor binding [GO:0042609]; CD8 receptor binding [GO:0042610]; disordered domain specific binding [GO:0097718]; enzyme binding [GO:0019899]; ephrin receptor binding [GO:0046875]; growth factor receptor binding [GO:0070851]; identical protein binding [GO:0042802]; ion channel binding [GO:0044325]; metal ion binding [GO:0046872]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; peptide hormone receptor binding [GO:0051428]; phosphatidylinositol 3-kinase binding [GO:0043548]; phospholipase activator activity [GO:0016004]; phospholipase binding [GO:0043274]; protein tyrosine kinase activity [GO:0004713]; signaling receptor binding [GO:0005102]; tau protein binding [GO:0048156]; tau-protein kinase activity [GO:0050321]; T cell receptor binding [GO:0042608]; transmembrane receptor protein tyrosine kinase activity [GO:0004714]; type 5 metabotropic glutamate receptor binding [GO:0031802] GO:0000165; GO:0000304; GO:0001764; GO:0002223; GO:0002250; GO:0002862; GO:0003015; GO:0004713; GO:0004714; GO:0004715; GO:0005102; GO:0005524; GO:0005634; GO:0005739; GO:0005768; GO:0005829; GO:0005884; GO:0005886; GO:0006468; GO:0006816; GO:0007169; GO:0007411; GO:0007596; GO:0007612; GO:0007631; GO:0008360; GO:0010629; GO:0010730; GO:0010976; GO:0014068; GO:0014069; GO:0016004; GO:0018108; GO:0019221; GO:0019899; GO:0030154; GO:0030168; GO:0030425; GO:0030900; GO:0031234; GO:0031295; GO:0031397; GO:0031802; GO:0035556; GO:0036120; GO:0038096; GO:0042177; GO:0042493; GO:0042531; GO:0042542; GO:0042608; GO:0042609; GO:0042610; GO:0042802; GO:0043014; GO:0043123; GO:0043274; GO:0043524; GO:0043548; GO:0044297; GO:0044325; GO:0045087; GO:0045121; GO:0045471; GO:0046777; GO:0046872; GO:0046875; GO:0048010; GO:0048013; GO:0048156; GO:0048471; GO:0048813; GO:0050321; GO:0050690; GO:0050730; GO:0050798; GO:0050804; GO:0050852; GO:0050900; GO:0050966; GO:0051428; GO:0051897; GO:0070851; GO:0071375; GO:0071560; GO:0090314; GO:0097038; GO:0097062; GO:0097386; GO:0097718; GO:0098685; GO:0098978; GO:0099092; GO:1900182; GO:1900449; GO:1901216; GO:1902951; GO:1903202; GO:1903997; GO:1904645; GO:1904646; GO:1905232; GO:1905430; GO:1905477; GO:1905664; GO:2001056; GO:2001240 PF07714;PF00017;PF00018; IPR035750;IPR011009;IPR000719;IPR017441;IPR001245;IPR000980;IPR036860;IPR036028;IPR001452;IPR008266;IPR020635; 7 P29728 2'-5'-oligoadenylate synthase 2 ((2-5')oligo(A) synthase 2) (2-5A synthase 2) (EC 2.7.7.84) (p69 OAS / p71 OAS) (p69OAS / p71OAS) Homo sapiens (Human) GNTAIAKK cytoplasm [GO:0005737]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471] defense response to bacterium [GO:0042742]; defense response to virus [GO:0051607]; interferon-gamma-mediated signaling pathway [GO:0060333]; interleukin-27-mediated signaling pathway [GO:0070106]; negative regulation of viral genome replication [GO:0045071]; nucleobase-containing compound metabolic process [GO:0006139]; positive regulation of interferon-beta production [GO:0032728]; positive regulation of tumor necrosis factor production [GO:0032760]; regulation of lactation [GO:1903487]; regulation of ribonuclease activity [GO:0060700]; response to virus [GO:0009615]; RNA catabolic process [GO:0006401]; type I interferon signaling pathway [GO:0060337] 2'-5'-oligoadenylate synthetase activity [GO:0001730]; ATP binding [GO:0005524]; double-stranded RNA binding [GO:0003725]; metal ion binding [GO:0046872] GO:0001730; GO:0003725; GO:0005524; GO:0005654; GO:0005737; GO:0005829; GO:0006139; GO:0006401; GO:0009615; GO:0016020; GO:0032728; GO:0032760; GO:0042742; GO:0043231; GO:0045071; GO:0046872; GO:0048471; GO:0051607; GO:0060333; GO:0060337; GO:0060700; GO:0070106; GO:1903487 PF01909;PF10421; IPR018952;IPR038121;IPR026774;IPR006117;IPR043518;IPR006116;IPR043519;IPR002934; 7 P62191 26S proteasome regulatory subunit 4 (P26s4) (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1) Homo sapiens (Human) GNAAAAKK cytosol [GO:0005829]; membrane [GO:0016020]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; proteasome accessory complex [GO:0022624]; proteasome complex [GO:0000502]; proteasome regulatory particle, base subcomplex [GO:0008540] anaphase-promoting complex-dependent catabolic process [GO:0031145]; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [GO:0002479]; Fc-epsilon receptor signaling pathway [GO:0038095]; interleukin-1-mediated signaling pathway [GO:0070498]; MAPK cascade [GO:0000165]; negative regulation of canonical Wnt signaling pathway [GO:0090090]; negative regulation of G2/M transition of mitotic cell cycle [GO:0010972]; negative regulation of neuron death [GO:1901215]; NIK/NF-kappaB signaling [GO:0038061]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; post-translational protein modification [GO:0043687]; pre-replicative complex assembly [GO:0036388]; proteasome-mediated ubiquitin-dependent protein catabolic process [GO:0043161]; protein deubiquitination [GO:0016579]; protein folding [GO:0006457]; protein polyubiquitination [GO:0000209]; regulation of cellular amino acid metabolic process [GO:0006521]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of mitotic cell cycle phase transition [GO:1901990]; regulation of mRNA stability [GO:0043488]; regulation of transcription from RNA polymerase II promoter in response to hypoxia [GO:0061418]; SCF-dependent proteasomal ubiquitin-dependent protein catabolic process [GO:0031146]; stimulatory C-type lectin receptor signaling pathway [GO:0002223]; T cell receptor signaling pathway [GO:0050852]; transmembrane transport [GO:0055085]; tumor necrosis factor-mediated signaling pathway [GO:0033209]; Wnt signaling pathway, planar cell polarity pathway [GO:0060071] ATPase activity [GO:0016887]; ATP binding [GO:0005524]; proteasome-activating ATPase activity [GO:0036402]; RNA binding [GO:0003723]; TBP-class protein binding [GO:0017025] GO:0000165; GO:0000209; GO:0000502; GO:0002223; GO:0002479; GO:0003723; GO:0005524; GO:0005634; GO:0005654; GO:0005829; GO:0006457; GO:0006521; GO:0008540; GO:0010972; GO:0016020; GO:0016579; GO:0016887; GO:0017025; GO:0022624; GO:0031145; GO:0031146; GO:0033209; GO:0036388; GO:0036402; GO:0038061; GO:0038095; GO:0043161; GO:0043488; GO:0043687; GO:0050852; GO:0055085; GO:0060071; GO:0061418; GO:0070498; GO:0090090; GO:0090263; GO:1901215; GO:1901990; GO:1902036 PF00004;PF17862;PF16450; IPR005937;IPR035244;IPR003593;IPR041569;IPR003959;IPR003960;IPR027417;IPR032501; 7 P09108 43 kDa receptor-associated protein of the synapse (RAPsyn) (43 kDa postsynaptic protein) (Acetylcholine receptor-associated 43 kDa protein) Tetronarce californica (Pacific electric ray) (Torpedo californica) GNAATAKK cytoplasm [GO:0005737]; cytoskeleton [GO:0005856]; postsynaptic membrane [GO:0045211] chemical synaptic transmission [GO:0007268] acetylcholine receptor binding [GO:0033130]; metal ion binding [GO:0046872]; protein-membrane adaptor activity [GO:0043495] GO:0005737; GO:0005856; GO:0007268; GO:0033130; GO:0043495; GO:0045211; GO:0046872 PF10579;PF13176;PF13639; IPR001237;IPR018293;IPR019568;IPR013026;IPR011990;IPR019734;IPR001841;IPR013083; 7 Q920K5 Brain and acute leukemia cytoplasmic protein Rattus norvegicus (Rat) GNMDGKAV cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane raft [GO:0045121]; neuron projection [GO:0043005]; nucleoplasm [GO:0005654]; postsynaptic density [GO:0014069] GO:0005654; GO:0005737; GO:0005829; GO:0014069; GO:0043005; GO:0045121 PF06989; IPR009728; 7 Q9P203 BTB/POZ domain-containing protein 7 Homo sapiens (Human) GCIGSRTV nucleus [GO:0005634] morphogenesis of a branching epithelium [GO:0061138]; multicellular organism development [GO:0007275]; regulation of branching involved in salivary gland morphogenesis [GO:0060693] GO:0005634; GO:0007275; GO:0060693; GO:0061138 PF07707;PF00651; IPR011705;IPR000210;IPR042345;IPR011333; 7 P25296 Calcineurin subunit B (Calcineurin regulatory subunit) (Protein phosphatase 2B regulatory subunit) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) GCGGSRAD calcineurin complex [GO:0005955] adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion [GO:0000754]; cellular ion homeostasis [GO:0006873]; fungal-type cell wall organization [GO:0031505]; protein dephosphorylation [GO:0006470] calcium-dependent protein serine/threonine phosphatase regulator activity [GO:0008597]; calcium ion binding [GO:0005509] GO:0000754; GO:0005509; GO:0005955; GO:0006470; GO:0006873; GO:0008597; GO:0031505 PF13499; IPR015757;IPR011992;IPR018247;IPR002048; 7 Q38872 Calcium-dependent protein kinase 6 (EC 2.7.11.1) (Calcium-dependent protein kinase isoform CDPK3) (AtCDPK3) (Calmodulin-domain protein kinase CDPK isoform 6) Arabidopsis thaliana (Mouse-ear cress) GQSQSGGH cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleus [GO:0005634]; plasma membrane [GO:0005886] abscisic acid-activated signaling pathway [GO:0009738]; intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105]; protein autophosphorylation [GO:0046777]; regulation of anion channel activity [GO:0010359]; regulation of stomatal movement [GO:0010119]; regulation of stomatal opening [GO:1902456]; response to abscisic acid [GO:0009737] ATP binding [GO:0005524]; calcium-dependent protein serine/threonine kinase activity [GO:0009931]; calcium ion binding [GO:0005509]; calmodulin binding [GO:0005516]; calmodulin-dependent protein kinase activity [GO:0004683]; protein serine/threonine kinase activity [GO:0004674]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0004674; GO:0004683; GO:0005509; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0009737; GO:0009738; GO:0009931; GO:0010119; GO:0010359; GO:0016020; GO:0018105; GO:0035556; GO:0046777; GO:0106310; GO:0106311; GO:1902456 PF13499;PF00069; IPR011992;IPR018247;IPR002048;IPR011009;IPR000719;IPR017441;IPR008271; 7 P17612 cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11) Homo sapiens (Human) GNIMDGKS acrosomal vesicle [GO:0001669]; calcium channel complex [GO:0034704]; cAMP-dependent protein kinase complex [GO:0005952]; centrosome [GO:0005813]; ciliary base [GO:0097546]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendritic spine [GO:0043197]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; mitochondrion [GO:0005739]; neuromuscular junction [GO:0031594]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleotide-activated protein kinase complex [GO:0031588]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane raft [GO:0044853]; sperm flagellum [GO:0036126]; sperm midpiece [GO:0097225] activation of protein kinase A activity [GO:0034199]; adaptive immune response [GO:0002250]; blood coagulation [GO:0007596]; calcium-mediated signaling using intracellular calcium source [GO:0035584]; cell communication by electrical coupling involved in cardiac conduction [GO:0086064]; cellular response to epinephrine stimulus [GO:0071872]; cellular response to glucagon stimulus [GO:0071377]; cellular response to glucose stimulus [GO:0071333]; cellular response to heat [GO:0034605]; cellular response to parathyroid hormone stimulus [GO:0071374]; chemical synaptic transmission [GO:0007268]; ciliary basal body-plasma membrane docking [GO:0097711]; cytokine-mediated signaling pathway [GO:0019221]; G2/M transition of mitotic cell cycle [GO:0000086]; high-density lipoprotein particle assembly [GO:0034380]; mesoderm formation [GO:0001707]; modulation of chemical synaptic transmission [GO:0050804]; mRNA processing [GO:0006397]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; neural tube closure [GO:0001843]; peptidyl-serine phosphorylation [GO:0018105]; peptidyl-threonine phosphorylation [GO:0018107]; positive regulation of cell cycle arrest [GO:0071158]; positive regulation of protein export from nucleus [GO:0046827]; protein autophosphorylation [GO:0046777]; protein kinase A signaling [GO:0010737]; protein phosphorylation [GO:0006468]; regulation of bicellular tight junction assembly [GO:2000810]; regulation of cardiac conduction [GO:1903779]; regulation of cardiac muscle contraction [GO:0055117]; regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [GO:0010881]; regulation of cytosolic calcium ion concentration [GO:0051480]; regulation of G2/M transition of mitotic cell cycle [GO:0010389]; regulation of heart rate [GO:0002027]; regulation of macroautophagy [GO:0016241]; regulation of osteoblast differentiation [GO:0045667]; regulation of proteasomal protein catabolic process [GO:0061136]; regulation of protein binding [GO:0043393]; regulation of protein processing [GO:0070613]; regulation of ryanodine-sensitive calcium-release channel activity [GO:0060314]; renal water homeostasis [GO:0003091]; sperm capacitation [GO:0048240]; stimulatory C-type lectin receptor signaling pathway [GO:0002223] AMP-activated protein kinase activity [GO:0004679]; ATP binding [GO:0005524]; cAMP-dependent protein kinase activity [GO:0004691]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; protein domain specific binding [GO:0019904]; protein kinase activity [GO:0004672]; protein kinase A regulatory subunit binding [GO:0034237]; protein kinase binding [GO:0019901]; protein serine/threonine/tyrosine kinase activity [GO:0004712]; protein serine/threonine kinase activity [GO:0004674]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311]; ubiquitin protein ligase binding [GO:0031625] GO:0000086; GO:0000287; GO:0001669; GO:0001707; GO:0001843; GO:0002027; GO:0002223; GO:0002250; GO:0002862; GO:0003091; GO:0004672; GO:0004674; GO:0004679; GO:0004691; GO:0004712; GO:0005524; GO:0005634; GO:0005654; GO:0005737; GO:0005739; GO:0005813; GO:0005829; GO:0005952; GO:0006397; GO:0006468; GO:0007268; GO:0007596; GO:0010389; GO:0010737; GO:0010881; GO:0016020; GO:0016241; GO:0016607; GO:0018105; GO:0018107; GO:0019221; GO:0019901; GO:0019904; GO:0030145; GO:0031588; GO:0031594; GO:0031625; GO:0034199; GO:0034237; GO:0034380; GO:0034605; GO:0034704; GO:0035584; GO:0036126; GO:0043197; GO:0043393; GO:0044853; GO:0045667; GO:0046777; GO:0046827; GO:0048240; GO:0048471; GO:0050804; GO:0051480; GO:0055117; GO:0060314; GO:0061136; GO:0070062; GO:0070613; GO:0071158; GO:0071333; GO:0071374; GO:0071377; GO:0071872; GO:0086064; GO:0097225; GO:0097546; GO:0097711; GO:0106310; GO:0106311; GO:1901621; GO:1903779; GO:2000810 PF00069; IPR000961;IPR011009;IPR000719;IPR017441;IPR008271;IPR044109; 7 P68181 cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11) Mus musculus (Mouse) GQDQTKQQ cAMP-dependent protein kinase complex [GO:0005952]; centrosome [GO:0005813]; ciliary base [GO:0097546]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; neural tube closure [GO:0001843]; protein kinase A signaling [GO:0010737]; protein phosphorylation [GO:0006468]; regulation of protein processing [GO:0070613]; response to clozapine [GO:0097338] AMP-activated protein kinase activity [GO:0004679]; ATP binding [GO:0005524]; cAMP-dependent protein kinase activity [GO:0004691]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311]; ubiquitin protein ligase binding [GO:0031625] GO:0000287; GO:0001843; GO:0004679; GO:0004691; GO:0005524; GO:0005634; GO:0005737; GO:0005813; GO:0005829; GO:0005886; GO:0005952; GO:0006468; GO:0007188; GO:0010737; GO:0031625; GO:0048471; GO:0051447; GO:0070613; GO:0097338; GO:0097546; GO:0106310; GO:0106311; GO:1901621 PF00069; IPR000961;IPR011009;IPR000719;IPR017441;IPR008271;IPR044109; 7 P22694 cAMP-dependent protein kinase catalytic subunit beta (PKA C-beta) (EC 2.7.11.11) Homo sapiens (Human) GAKQSGPA cAMP-dependent protein kinase complex [GO:0005952]; centrosome [GO:0005813]; ciliary base [GO:0097546]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; synapse [GO:0045202] activation of protein kinase A activity [GO:0034199]; adaptive immune response [GO:0002250]; adenylate cyclase-modulating G protein-coupled receptor signaling pathway [GO:0007188]; blood coagulation [GO:0007596]; cellular response to glucagon stimulus [GO:0071377]; chemical synaptic transmission [GO:0007268]; high-density lipoprotein particle assembly [GO:0034380]; negative regulation of inflammatory response to antigenic stimulus [GO:0002862]; negative regulation of meiotic cell cycle [GO:0051447]; negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning [GO:1901621]; neural tube closure [GO:0001843]; protein kinase A signaling [GO:0010737]; protein phosphorylation [GO:0006468]; regulation of protein processing [GO:0070613]; renal water homeostasis [GO:0003091]; response to clozapine [GO:0097338]; signal transduction [GO:0007165]; stimulatory C-type lectin receptor signaling pathway [GO:0002223] AMP-activated protein kinase activity [GO:0004679]; ATP binding [GO:0005524]; cAMP-dependent protein kinase activity [GO:0004691]; magnesium ion binding [GO:0000287]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311]; ubiquitin protein ligase binding [GO:0031625] GO:0000287; GO:0001843; GO:0002223; GO:0002250; GO:0002862; GO:0003091; GO:0004679; GO:0004691; GO:0005524; GO:0005634; GO:0005654; GO:0005813; GO:0005829; GO:0005886; GO:0005952; GO:0006468; GO:0007165; GO:0007188; GO:0007268; GO:0007596; GO:0010737; GO:0031625; GO:0034199; GO:0034380; GO:0045202; GO:0048471; GO:0051447; GO:0070062; GO:0070613; GO:0071377; GO:0097338; GO:0097546; GO:0106310; GO:0106311; GO:1901621 PF00069; IPR000961;IPR011009;IPR000719;IPR017441;IPR008271;IPR044109; 7 O00408 cGMP-dependent 3',5'-cyclic phosphodiesterase (EC 3.1.4.17) (Cyclic GMP-stimulated phosphodiesterase) (CGS-PDE) (cGSPDE) Homo sapiens (Human) GNSCRGSF cytoplasm [GO:0005737]; cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; Golgi apparatus [GO:0005794]; mitochondrial inner membrane [GO:0005743]; mitochondrial matrix [GO:0005759]; mitochondrial outer membrane [GO:0005741]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; synaptic membrane [GO:0097060] adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway [GO:0007193]; aorta development [GO:0035904]; cAMP-mediated signaling [GO:0019933]; cellular response to 2,3,7,8-tetrachlorodibenzodioxine [GO:1904613]; cellular response to cAMP [GO:0071320]; cellular response to cGMP [GO:0071321]; cellular response to drug [GO:0035690]; cellular response to granulocyte macrophage colony-stimulating factor stimulus [GO:0097011]; cellular response to macrophage colony-stimulating factor stimulus [GO:0036006]; cellular response to mechanical stimulus [GO:0071260]; cellular response to transforming growth factor beta stimulus [GO:0071560]; cGMP catabolic process [GO:0046069]; cGMP-mediated signaling [GO:0019934]; establishment of endothelial barrier [GO:0061028]; G protein-coupled receptor signaling pathway [GO:0007186]; heart valve development [GO:0003170]; monocyte differentiation [GO:0030224]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of cGMP-mediated signaling [GO:0010754]; negative regulation of transcription by RNA polymerase II [GO:0000122]; negative regulation of vascular permeability [GO:0043116]; positive regulation of gene expression [GO:0010628]; positive regulation of inflammatory response [GO:0050729]; positive regulation of vascular permeability [GO:0043117]; regulation of cAMP-mediated signaling [GO:0043949]; regulation of cGMP-mediated signaling [GO:0010752]; regulation of mitochondrion organization [GO:0010821]; signal transduction [GO:0007165]; ventricular septum development [GO:0003281] 3',5'-cyclic-AMP phosphodiesterase activity [GO:0004115]; 3',5'-cyclic-GMP phosphodiesterase activity [GO:0047555]; 3',5'-cyclic-nucleotide phosphodiesterase activity [GO:0004114]; cAMP binding [GO:0030552]; cGMP binding [GO:0030553]; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity [GO:0004118]; identical protein binding [GO:0042802]; magnesium ion binding [GO:0000287]; phosphate ion binding [GO:0042301]; protein homodimerization activity [GO:0042803]; TPR domain binding [GO:0030911]; zinc ion binding [GO:0008270] GO:0000122; GO:0000287; GO:0003170; GO:0003281; GO:0004114; GO:0004115; GO:0004118; GO:0005634; GO:0005737; GO:0005741; GO:0005743; GO:0005759; GO:0005783; GO:0005794; GO:0005829; GO:0005886; GO:0007165; GO:0007186; GO:0007193; GO:0008270; GO:0010628; GO:0010752; GO:0010754; GO:0010821; GO:0019933; GO:0019934; GO:0030224; GO:0030552; GO:0030553; GO:0030911; GO:0035690; GO:0035904; GO:0036006; GO:0042301; GO:0042734; GO:0042802; GO:0042803; GO:0043116; GO:0043117; GO:0043949; GO:0043951; GO:0046069; GO:0047555; GO:0048471; GO:0050729; GO:0061028; GO:0071260; GO:0071320; GO:0071321; GO:0071560; GO:0097011; GO:0097060; GO:1904613 PF01590;PF13185;PF00233; IPR003018;IPR029016;IPR003607;IPR023088;IPR002073;IPR036971;IPR023174; 7 Q96PX1 E3 ubiquitin ligase RNF157 (EC 2.3.2.27) (RING finger protein 157) (RING-type E3 ubiquitin transferase RNF157) Homo sapiens (Human) GNQLAGIA cell body [GO:0044297]; cytoplasm [GO:0005737]; early endosome [GO:0005769]; nucleus [GO:0005634]; plasma membrane [GO:0005886] endosome to lysosome transport [GO:0008333]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cAMP-mediated signaling [GO:0043951]; negative regulation of G protein-coupled receptor signaling pathway [GO:0045744]; positive regulation of dendrite extension [GO:1903861]; protein autoubiquitination [GO:0051865]; protein ubiquitination [GO:0016567] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] GO:0005634; GO:0005737; GO:0005769; GO:0005886; GO:0008333; GO:0016567; GO:0043066; GO:0043951; GO:0044297; GO:0045744; GO:0046872; GO:0051865; GO:0061630; GO:1903861 IPR001841;IPR013083; 7 Q8NHG8 E3 ubiquitin-protein ligase ZNRF2 (EC 2.3.2.27) (Protein Ells2) (RING finger protein 202) (RING-type E3 ubiquitin transferase ZNRF2) (Zinc/RING finger protein 2) Homo sapiens (Human) GAAPSKIV cell projection [GO:0042995]; cytoplasm [GO:0005737]; cytoplasmic vesicle membrane [GO:0030659]; cytosol [GO:0005829]; endosome membrane [GO:0010008]; fibrillar center [GO:0001650]; intracellular membrane-bounded organelle [GO:0043231]; lysosomal membrane [GO:0005765]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886]; presynaptic membrane [GO:0042734]; protein-containing complex [GO:0032991] protein polyubiquitination [GO:0000209] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630] GO:0000209; GO:0001650; GO:0005654; GO:0005737; GO:0005765; GO:0005829; GO:0005886; GO:0010008; GO:0030659; GO:0032991; GO:0042734; GO:0042995; GO:0043231; GO:0046872; GO:0061630 PF13639; IPR001841;IPR013083; 7 P79880 Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A) Gallus gallus (Chicken) GQACGHSI cone photoreceptor outer segment [GO:0120199]; photoreceptor inner segment [GO:0001917] cellular response to calcium ion [GO:0071277]; positive regulation of guanylate cyclase activity [GO:0031284]; visual perception [GO:0007601] calcium ion binding [GO:0005509]; calcium sensitive guanylate cyclase activator activity [GO:0008048]; guanylate cyclase regulator activity [GO:0030249] GO:0001917; GO:0005509; GO:0007601; GO:0008048; GO:0030249; GO:0031284; GO:0071277; GO:0120199 PF13499;PF13833; IPR011992;IPR018247;IPR002048;IPR033022;IPR028846; 7 P46065 Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A) Bos taurus (Bovine) GNSASNIV cone photoreceptor outer segment [GO:0120199]; membrane [GO:0016020]; photoreceptor inner segment [GO:0001917] cellular response to calcium ion [GO:0071277]; phototransduction [GO:0007602]; positive regulation of guanylate cyclase activity [GO:0031284]; regulation of guanylate cyclase activity [GO:0031282]; visual perception [GO:0007601] calcium ion binding [GO:0005509]; calcium sensitive guanylate cyclase activator activity [GO:0008048]; guanylate cyclase regulator activity [GO:0030249] GO:0001917; GO:0005509; GO:0007601; GO:0007602; GO:0008048; GO:0016020; GO:0030249; GO:0031282; GO:0031284; GO:0071277; GO:0120199 PF13499;PF13833; IPR011992;IPR018247;IPR002048;IPR033022;IPR028846; 7 Q9UJ68 Mitochondrial peptide methionine sulfoxide reductase (EC 1.8.4.11) (Peptide-methionine (S)-S-oxide reductase) (Peptide Met(O) reductase) (Protein-methionine-S-oxide reductase) (PMSR) Homo sapiens (Human) GNGESQLS actin cytoskeleton [GO:0015629]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; mitochondrion [GO:0005739]; nucleoplasm [GO:0005654]; plasma membrane [GO:0005886] cellular protein modification process [GO:0006464]; cellular response to oxidative stress [GO:0034599]; methionine metabolic process [GO:0006555]; protein repair [GO:0030091]; response to oxidative stress [GO:0006979] L-methionine-(S)-S-oxide reductase activity [GO:0036456]; peptide-methionine (S)-S-oxide reductase activity [GO:0008113] GO:0005654; GO:0005737; GO:0005739; GO:0005829; GO:0005886; GO:0006464; GO:0006555; GO:0006979; GO:0008113; GO:0015629; GO:0030091; GO:0034599; GO:0036456; GO:0070062 PF01625; IPR002569;IPR036509; 7 Q99570 Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) Homo sapiens (Human) GANTSRKP autophagosome [GO:0005776]; axoneme [GO:0005930]; cytosol [GO:0005829]; intracellular membrane-bounded organelle [GO:0043231]; late endosome [GO:0005770]; membrane [GO:0016020]; microtubule cytoskeleton [GO:0015630]; nucleus-vacuole junction [GO:0071561]; phagocytic vesicle membrane [GO:0030670]; phosphatidylinositol 3-kinase complex, class III [GO:0035032]; phosphatidylinositol 3-kinase complex, class III, type I [GO:0034271]; phosphatidylinositol 3-kinase complex, class III, type II [GO:0034272] autophagy of peroxisome [GO:0030242]; cellular response to glucose starvation [GO:0042149]; late endosome to vacuole transport [GO:0045324]; macroautophagy [GO:0016236]; phosphatidylinositol biosynthetic process [GO:0006661]; positive regulation of phosphatidylinositol 3-kinase activity [GO:0043552]; protein phosphorylation [GO:0006468]; protein targeting to vacuole [GO:0006623]; receptor catabolic process [GO:0032801]; regulation of cytokinesis [GO:0032465]; toll-like receptor 9 signaling pathway [GO:0034162] ATP binding [GO:0005524]; protein kinase activity [GO:0004672]; protein serine/threonine kinase activity [GO:0004674]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0004672; GO:0004674; GO:0005524; GO:0005770; GO:0005776; GO:0005829; GO:0005930; GO:0006468; GO:0006623; GO:0006661; GO:0015630; GO:0016020; GO:0016236; GO:0030242; GO:0030670; GO:0032465; GO:0032801; GO:0034162; GO:0034271; GO:0034272; GO:0035032; GO:0042149; GO:0043231; GO:0043552; GO:0045324; GO:0071561; GO:0106310; GO:0106311 PF00069;PF00400; IPR011989;IPR016024;IPR021133;IPR011009;IPR000719;IPR008271;IPR015943;IPR001680;IPR019775;IPR017986;IPR036322; 7 Q86XD5 Protein FAM131B Homo sapiens (Human) GANASNYP cytosol [GO:0005829]; nucleoplasm [GO:0005654] GO:0005654; GO:0005829 PF15010; IPR026782; 7 Q8WU08 Serine/threonine-protein kinase 32A (EC 2.7.11.1) (Yet another novel kinase 1) Homo sapiens (Human) GALTSRQH plasma membrane [GO:0005886] intracellular signal transduction [GO:0035556]; peptidyl-serine phosphorylation [GO:0018105] ATP binding [GO:0005524]; metal ion binding [GO:0046872]; protein serine/threonine kinase activity [GO:0004674]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0004674; GO:0005524; GO:0005886; GO:0018105; GO:0035556; GO:0046872; GO:0106310; GO:0106311 PF00069; IPR011009;IPR000719;IPR017441;IPR008271; 8 Q8TB92 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic (EC 4.1.3.4) (3-hydroxy-3-methylglutaryl-CoA lyase-like protein 1) (HMGCL-like 1) (Endoplasmic reticulum 3-hydroxy-3-methylglutaryl-CoA lyase) (er-cHL) Homo sapiens (Human) GCGTSKVL cytosol [GO:0005829]; endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; membrane [GO:0016020]; perinuclear region of cytoplasm [GO:0048471] ketone body biosynthetic process [GO:0046951]; leucine catabolic process [GO:0006552]; lipid metabolic process [GO:0006629] hydroxymethylglutaryl-CoA lyase activity [GO:0004419]; metal ion binding [GO:0046872] GO:0004419; GO:0005783; GO:0005789; GO:0005829; GO:0006552; GO:0006629; GO:0016020; GO:0046872; GO:0046951; GO:0048471 PF00682; IPR013785;IPR030021;IPR043594;IPR000891; 8 Q7FZF1 Calcineurin B-like protein 5 (SOS3-like calcium-binding protein 4) Arabidopsis thaliana (Mouse-ear cress) GCVCSKQL cytoplasm [GO:0005737]; nucleus [GO:0005634] calcium-mediated signaling [GO:0019722]; response to osmotic stress [GO:0006970]; response to salt stress [GO:0009651]; response to water deprivation [GO:0009414] calcium ion binding [GO:0005509] GO:0005509; GO:0005634; GO:0005737; GO:0006970; GO:0009414; GO:0009651; GO:0019722 PF12763;PF13499; IPR011992;IPR002048;IPR000261; 8 Q5M775 Cytospin-B (Nuclear structure protein 5) (NSP5) (Sperm antigen HCMOGT-1) (Sperm antigen with calponin homology and coiled-coil domains 1) Homo sapiens (Human) GNGMTKVL cytosol [GO:0005829]; fibrillar center [GO:0001650]; filamentous actin [GO:0031941]; intracellular membrane-bounded organelle [GO:0043231]; membrane [GO:0016020]; microtubule organizing center [GO:0005815]; nucleoplasm [GO:0005654] actin cytoskeleton organization [GO:0030036] GO:0001650; GO:0005654; GO:0005815; GO:0005829; GO:0016020; GO:0030036; GO:0031941; GO:0043231 PF00307; IPR001715;IPR036872; 8 Q9H1R2 Dual specificity protein phosphatase 15 (EC 3.1.3.16) (EC 3.1.3.48) (VH1-related member Y) (Vaccinia virus VH1-related dual-specific protein phosphatase Y) Homo sapiens (Human) GNGMNKIL cytosol [GO:0005829]; plasma membrane [GO:0005886] dephosphorylation [GO:0016311]; positive regulation of JNK cascade [GO:0046330]; regulation of cell population proliferation [GO:0042127]; transforming growth factor beta receptor signaling pathway [GO:0007179] phosphatase activity [GO:0016791]; protein serine phosphatase activity [GO:0106306]; protein threonine phosphatase activity [GO:0106307]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine phosphatase activity [GO:0004725] GO:0004725; GO:0005829; GO:0005886; GO:0007179; GO:0008138; GO:0016311; GO:0016791; GO:0042127; GO:0046330; GO:0106306; GO:0106307 IPR029021;IPR008984;IPR016130;IPR000387;IPR020422; 8 Q9NRW4 Dual specificity protein phosphatase 22 (EC 3.1.3.16) (EC 3.1.3.48) (JNK-stimulatory phosphatase-1) (JSP-1) (Low molecular weight dual specificity phosphatase 2) (LMW-DSP2) (Mitogen-activated protein kinase phosphatase x) (MAP kinase phosphatase x) (MKP-x) Homo sapiens (Human) GNSHCVPQ cytoplasm [GO:0005737]; cytosol [GO:0005829]; filamentous actin [GO:0031941]; leading edge of lamellipodium [GO:0061851]; nucleus [GO:0005634]; plasma membrane [GO:0005886] cellular response to epidermal growth factor stimulus [GO:0071364]; negative regulation of cell migration [GO:0030336]; negative regulation of focal adhesion assembly [GO:0051895]; negative regulation of non-membrane spanning protein tyrosine kinase activity [GO:1903996]; negative regulation of transcription by RNA polymerase II [GO:0000122]; peptidyl-tyrosine dephosphorylation [GO:0035335]; positive regulation of JNK cascade [GO:0046330]; regulation of cell population proliferation [GO:0042127]; transforming growth factor beta receptor signaling pathway [GO:0007179] non-membrane spanning protein tyrosine phosphatase activity [GO:0004726]; protein serine phosphatase activity [GO:0106306]; protein threonine phosphatase activity [GO:0106307]; protein tyrosine/serine/threonine phosphatase activity [GO:0008138]; protein tyrosine kinase binding [GO:1990782]; protein tyrosine phosphatase activity [GO:0004725] GO:0000122; GO:0004725; GO:0004726; GO:0005634; GO:0005737; GO:0005829; GO:0005886; GO:0007179; GO:0008138; GO:0030336; GO:0031941; GO:0035335; GO:0042127; GO:0046330; GO:0051895; GO:0061851; GO:0071364; GO:0106306; GO:0106307; GO:1903996; GO:1990782 IPR029021;IPR000387;IPR020422; 8 O00461 Golgi integral membrane protein 4 (Golgi integral membrane protein, cis) (GIMPc) (Golgi phosphoprotein 4) (Golgi-localized phosphoprotein of 130 kDa) (Golgi phosphoprotein of 130 kDa) Homo sapiens (Human) GNSHHKRK cis-Golgi network [GO:0005801]; endocytic vesicle [GO:0030139]; endosome membrane [GO:0010008]; Golgi apparatus [GO:0005794]; Golgi cisterna membrane [GO:0032580]; Golgi lumen [GO:0005796]; Golgi membrane [GO:0000139]; integral component of membrane [GO:0016021]; membrane [GO:0016020]; transport vesicle [GO:0030133] GO:0000139; GO:0005794; GO:0005796; GO:0005801; GO:0010008; GO:0016020; GO:0016021; GO:0030133; GO:0030139; GO:0032580 IPR042336; 8 P03145 Large envelope protein (L glycoprotein) (L-HBsAg) (LHB) (Large S protein) (Large surface protein) (Major surface antigen) [Cleaved into: Truncated S protein (St)] Duck hepatitis B virus (strain United States/DHBV-16) (DHBV) GNVPSAVK integral component of membrane [GO:0016021]; virion membrane [GO:0055036] membrane fusion involved in viral entry into host cell [GO:0039663]; virion attachment to host cell [GO:0019062] GO:0016021; GO:0019062; GO:0039663; GO:0055036 PF00695; IPR000349; 8 P08473 Neprilysin (EC 3.4.24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10) Homo sapiens (Human) GNHSGRPE axon [GO:0030424]; brush border [GO:0005903]; cell surface [GO:0009986]; cytoplasm [GO:0005737]; cytoplasmic vesicle [GO:0031410]; dendrite [GO:0030425]; early endosome [GO:0005769]; extracellular exosome [GO:0070062]; focal adhesion [GO:0005925]; integral component of membrane [GO:0016021]; integral component of plasma membrane [GO:0005887]; membrane raft [GO:0045121]; neuronal cell body [GO:0043025]; neuron projection terminus [GO:0044306]; plasma membrane [GO:0005886]; presynapse [GO:0098793]; secretory granule membrane [GO:0030667]; synapse [GO:0045202]; synaptic vesicle [GO:0008021]; trans-Golgi network [GO:0005802] aging [GO:0007568]; amyloid-beta clearance [GO:0097242]; amyloid-beta clearance by cellular catabolic process [GO:0150094]; amyloid-beta metabolic process [GO:0050435]; angiotensin maturation [GO:0002003]; cellular response to cytokine stimulus [GO:0071345]; cellular response to UV-A [GO:0071492]; cellular response to UV-B [GO:0071493]; creatinine metabolic process [GO:0046449]; kidney development [GO:0001822]; learning or memory [GO:0007611]; lung development [GO:0030324]; neuropeptide processing [GO:0061837]; neutrophil degranulation [GO:0043312]; peptide metabolic process [GO:0006518]; placenta development [GO:0001890]; positive regulation of long-term synaptic potentiation [GO:1900273]; positive regulation of neurogenesis [GO:0050769]; protein processing [GO:0016485]; proteolysis [GO:0006508]; replicative senescence [GO:0090399]; sensory perception of pain [GO:0019233] cardiolipin binding [GO:1901612]; endopeptidase activity [GO:0004175]; exopeptidase activity [GO:0008238]; metalloendopeptidase activity [GO:0004222]; metallopeptidase activity [GO:0008237]; oligopeptidase activity [GO:0070012]; peptide binding [GO:0042277]; phosphatidylserine binding [GO:0001786]; protein homodimerization activity [GO:0042803]; zinc ion binding [GO:0008270] GO:0001786; GO:0001822; GO:0001890; GO:0002003; GO:0004175; GO:0004222; GO:0005737; GO:0005769; GO:0005802; GO:0005886; GO:0005887; GO:0005903; GO:0005925; GO:0006508; GO:0006518; GO:0007568; GO:0007611; GO:0008021; GO:0008237; GO:0008238; GO:0008270; GO:0009986; GO:0016021; GO:0016485; GO:0019233; GO:0030324; GO:0030424; GO:0030425; GO:0030667; GO:0031410; GO:0042277; GO:0042803; GO:0043025; GO:0043312; GO:0044306; GO:0045121; GO:0045202; GO:0046449; GO:0050435; GO:0050769; GO:0061837; GO:0070012; GO:0070062; GO:0071345; GO:0071492; GO:0071493; GO:0090399; GO:0097242; GO:0098793; GO:0150094; GO:1900273; GO:1901612 PF01431;PF05649; IPR024079;IPR029727;IPR000718;IPR018497;IPR042089;IPR008753; 8 P29473 Nitric oxide synthase, endothelial (EC 1.14.13.39) (Constitutive NOS) (cNOS) (EC-NOS) (Endothelial NOS) (eNOS) (NOS type III) (NOSIII) Bos taurus (Bovine) GQQPGKVL caveola [GO:0005901]; cytoskeleton [GO:0005856]; Golgi apparatus [GO:0005794] arginine catabolic process [GO:0006527]; blood coagulation [GO:0007596]; cellular response to laminar fluid shear stress [GO:0071499]; mitochondrion organization [GO:0007005]; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [GO:1902042]; negative regulation of leukocyte cell-cell adhesion [GO:1903038]; nitric oxide biosynthetic process [GO:0006809]; positive regulation of guanylate cyclase activity [GO:0031284] calmodulin binding [GO:0005516]; flavin adenine dinucleotide binding [GO:0050660]; FMN binding [GO:0010181]; heme binding [GO:0020037]; metal ion binding [GO:0046872]; NADP binding [GO:0050661]; nitric-oxide synthase activity [GO:0004517] GO:0004517; GO:0005516; GO:0005794; GO:0005856; GO:0005901; GO:0006527; GO:0006809; GO:0007005; GO:0007596; GO:0010181; GO:0020037; GO:0031284; GO:0046872; GO:0050660; GO:0050661; GO:0071499; GO:1902042; GO:1903038 PF00667;PF00258;PF00175;PF02898; IPR003097;IPR017927;IPR001094;IPR008254;IPR001709;IPR029039;IPR039261;IPR023173;IPR012144;IPR004030;IPR036119;IPR001433;IPR017938; 8 O60936 Nucleolar protein 3 (Apoptosis repressor with CARD) (Muscle-enriched cytoplasmic protein) (Myp) (Nucleolar protein of 30 kDa) (Nop30) Homo sapiens (Human) GQHPAKSM cytoplasm [GO:0005737]; cytosol [GO:0005829]; membrane [GO:0016020]; mitochondrion [GO:0005739]; nucleolus [GO:0005730]; sarcoplasmic reticulum [GO:0016529] blood vessel remodeling [GO:0001974]; cardiac muscle cell apoptotic process [GO:0010659]; inhibition of cysteine-type endopeptidase activity involved in apoptotic process [GO:1990001]; intrinsic apoptotic signaling pathway [GO:0097193]; mRNA splice site selection [GO:0006376]; negative regulation of apoptotic process [GO:0043066]; negative regulation of cardiac muscle cell apoptotic process [GO:0010667]; negative regulation of extrinsic apoptotic signaling pathway [GO:2001237]; negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway [GO:1903298]; negative regulation of mitochondrial membrane permeability involved in apoptotic process [GO:1902109]; negative regulation of muscle atrophy [GO:0014736]; negative regulation of necrotic cell death [GO:0060547]; negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [GO:1902176]; negative regulation of release of cytochrome c from mitochondria [GO:0090201]; negative regulation of tumor necrosis factor-mediated signaling pathway [GO:0010804]; protein complex oligomerization [GO:0051259]; regulation of NIK/NF-kappaB signaling [GO:1901222]; release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [GO:0014808]; response to hypoxia [GO:0001666]; response to injury involved in regulation of muscle adaptation [GO:0014876]; response to ischemia [GO:0002931]; RNA splicing [GO:0008380] calcium ion binding [GO:0005509]; caspase binding [GO:0089720]; cysteine-type endopeptidase inhibitor activity involved in apoptotic process [GO:0043027]; death effector domain binding [GO:0035877]; death receptor binding [GO:0005123]; identical protein binding [GO:0042802]; RNA binding [GO:0003723] GO:0001666; GO:0001974; GO:0002931; GO:0003723; GO:0005123; GO:0005509; GO:0005730; GO:0005737; GO:0005739; GO:0005829; GO:0006376; GO:0008380; GO:0010659; GO:0010667; GO:0010804; GO:0014736; GO:0014808; GO:0014876; GO:0016020; GO:0016529; GO:0035877; GO:0042802; GO:0043027; GO:0043066; GO:0051259; GO:0060547; GO:0089720; GO:0090201; GO:0097193; GO:1901222; GO:1902109; GO:1902176; GO:1903298; GO:1990001; GO:2001237 PF00619; IPR001315;IPR011029; 8 Q494U1 Pleckstrin homology domain-containing family N member 1 (PH domain-containing family N member 1) (Cardiolipin and phosphatidic acid-binding protein) Homo sapiens (Human) GKSESQMD cytoskeleton [GO:0005856]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739]; plasma membrane [GO:0005886] 3'-UTR-mediated mRNA destabilization [GO:0061158]; positive regulation of apoptotic process [GO:0043065]; response to hypoxia [GO:0001666] cardiolipin binding [GO:1901612]; phosphatidic acid binding [GO:0070300]; phosphatidylinositol phosphate binding [GO:1901981]; phosphatidylserine binding [GO:0001786] GO:0001666; GO:0001786; GO:0005739; GO:0005856; GO:0005886; GO:0031966; GO:0043065; GO:0061158; GO:0070300; GO:1901612; GO:1901981 IPR011993;IPR001849;IPR042835;IPR037839; 8 P16452 Protein 4.2 (P4.2) (Erythrocyte membrane protein band 4.2) (Erythrocyte protein 4.2) Homo sapiens (Human) GNVNAREE cortical cytoskeleton [GO:0030863]; cytoskeleton [GO:0005856]; plasma membrane [GO:0005886] cell morphogenesis [GO:0000902]; erythrocyte maturation [GO:0043249]; hemoglobin metabolic process [GO:0020027]; iron ion homeostasis [GO:0055072]; peptide cross-linking [GO:0018149]; regulation of cell shape [GO:0008360]; spleen development [GO:0048536] ATP binding [GO:0005524]; protein-glutamine gamma-glutamyltransferase activity [GO:0003810]; structural constituent of cytoskeleton [GO:0005200] GO:0000902; GO:0003810; GO:0005200; GO:0005524; GO:0005856; GO:0005886; GO:0008360; GO:0018149; GO:0020027; GO:0030863; GO:0043249; GO:0048536; GO:0055072 PF00927;PF01841;PF00868; IPR013783;IPR014756;IPR038765;IPR002931;IPR036985;IPR023608;IPR013808;IPR008958;IPR036238;IPR001102; 8 O75688 Protein phosphatase 1B (EC 3.1.3.16) (Protein phosphatase 2C isoform beta) (PP2C-beta) Homo sapiens (Human) GQALGIKS cytosol [GO:0005829]; membrane [GO:0016020]; nucleolus [GO:0005730]; nucleus [GO:0005634] negative regulation of defense response to virus [GO:0050687]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of interferon-beta production [GO:0032688]; negative regulation of NIK/NF-kappaB signaling [GO:1901223]; N-terminal protein myristoylation [GO:0006499]; peptidyl-threonine dephosphorylation [GO:0035970]; positive regulation of canonical Wnt signaling pathway [GO:0090263]; protein dephosphorylation [GO:0006470] magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; protein serine/threonine phosphatase activity [GO:0004722]; protein serine phosphatase activity [GO:0106306]; protein threonine phosphatase activity [GO:0106307] GO:0000287; GO:0004722; GO:0005634; GO:0005730; GO:0005829; GO:0006470; GO:0006499; GO:0016020; GO:0030145; GO:0032688; GO:0035970; GO:0043124; GO:0050687; GO:0090263; GO:0106306; GO:0106307; GO:1901223 PF00481;PF07830; IPR000222;IPR012911;IPR036580;IPR036457;IPR001932; 8 Q7LDG7 RAS guanyl-releasing protein 2 (Calcium and DAG-regulated guanine nucleotide exchange factor I) (CalDAG-GEFI) (Cdc25-like protein) (hCDC25L) (F25B3.3 kinase-like protein) Homo sapiens (Human) GAFLDKPK cytosol [GO:0005829]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; ruffle membrane [GO:0032587]; synapse [GO:0045202] adaptive immune response [GO:0002250]; cellular response to calcium ion [GO:0071277]; positive regulation of GTPase activity [GO:0043547]; Ras protein signal transduction [GO:0007265]; regulation of cell growth [GO:0001558]; signal transduction [GO:0007165] calcium ion binding [GO:0005509]; diacylglycerol binding [GO:0019992]; guanyl-nucleotide exchange factor activity [GO:0005085]; lipid binding [GO:0008289] GO:0001558; GO:0002250; GO:0005085; GO:0005509; GO:0005829; GO:0005886; GO:0007165; GO:0007265; GO:0008289; GO:0019992; GO:0032587; GO:0043005; GO:0043547; GO:0045202; GO:0071277 PF00130;PF13499;PF00617;PF00618; IPR011992;IPR018247;IPR002048;IPR002219;IPR008937;IPR000651;IPR023578;IPR001895;IPR036964; 8 Q8WVD5 RING finger protein 141 (Zinc finger protein 230) Homo sapiens (Human) GNLKSVGQ membrane [GO:0016020] protein autoubiquitination [GO:0051865]; regulation of transcription, DNA-templated [GO:0006355] metal ion binding [GO:0046872]; ubiquitin-protein transferase activity [GO:0004842] GO:0004842; GO:0006355; GO:0016020; GO:0046872; GO:0051865 IPR043400;IPR001841;IPR013083;IPR017907; 8 P11801 Serine/threonine-protein kinase H1 (EC 2.7.11.1) (Protein serine kinase H1) (PSK-H1) Homo sapiens (Human) GNGMCSRK cytosol [GO:0005829]; endoplasmic reticulum membrane [GO:0005789]; Golgi apparatus [GO:0005794]; microtubule organizing center [GO:0005815]; nuclear speck [GO:0016607]; plasma membrane [GO:0005886] determination of left/right symmetry [GO:0007368]; heart development [GO:0007507] ATP binding [GO:0005524]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311] GO:0005524; GO:0005789; GO:0005794; GO:0005815; GO:0005829; GO:0005886; GO:0007368; GO:0007507; GO:0016607; GO:0106310; GO:0106311 PF00069; IPR011009;IPR000719;IPR017441;IPR008271; 8 Q9SCY5 SNF1-related protein kinase regulatory subunit beta-2 (AKIN subunit beta-2) (AKINB2) (AKINbeta2) Arabidopsis thaliana (Mouse-ear cress) GNAQERPS plasma membrane [GO:0005886] carbohydrate metabolic process [GO:0005975]; fatty acid biosynthetic process [GO:0006633]; nitrate assimilation [GO:0042128] ATP binding [GO:0005524] GO:0005524; GO:0005886; GO:0005975; GO:0006633; GO:0042128 PF16561;PF04739; IPR032640;IPR006828;IPR037256;IPR013783;IPR014756;IPR043554; 8 P00519 Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150) Homo sapiens (Human) GQQISDQT actin cytoskeleton [GO:0015629]; cell leading edge [GO:0031252]; cytoplasm [GO:0005737]; cytosol [GO:0005829]; dendrite [GO:0030425]; mitochondrion [GO:0005739]; neuronal cell body [GO:0043025]; nuclear body [GO:0016604]; nuclear membrane [GO:0031965]; nucleolus [GO:0005730]; nucleoplasm [GO:0005654]; nucleus [GO:0005634]; perinuclear region of cytoplasm [GO:0048471]; postsynapse [GO:0098794]; protein-containing complex [GO:0032991] actin cytoskeleton organization [GO:0030036]; actin filament branching [GO:0090135]; activated T cell proliferation [GO:0050798]; activation of protein kinase C activity [GO:1990051]; alpha-beta T cell differentiation [GO:0046632]; autophagy [GO:0006914]; B-1 B cell homeostasis [GO:0001922]; B cell proliferation involved in immune response [GO:0002322]; B cell receptor signaling pathway [GO:0050853]; Bergmann glial cell differentiation [GO:0060020]; cell cycle arrest [GO:0007050]; cellular protein modification process [GO:0006464]; cellular response to DNA damage stimulus [GO:0006974]; cellular response to dopamine [GO:1903351]; cellular response to hydrogen peroxide [GO:0070301]; cellular response to lipopolysaccharide [GO:0071222]; cellular response to oxidative stress [GO:0034599]; cerebellum morphogenesis [GO:0021587]; circulatory system development [GO:0072359]; collateral sprouting [GO:0048668]; DNA conformation change [GO:0071103]; DNA damage induced protein phosphorylation [GO:0006975]; endocytosis [GO:0006897]; endothelial cell migration [GO:0043542]; epidermal growth factor receptor signaling pathway [GO:0007173]; establishment of protein localization [GO:0045184]; Fc-gamma receptor signaling pathway involved in phagocytosis [GO:0038096]; integrin-mediated signaling pathway [GO:0007229]; intrinsic apoptotic signaling pathway in response to DNA damage [GO:0008630]; microspike assembly [GO:0030035]; mismatch repair [GO:0006298]; mitochondrial depolarization [GO:0051882]; mitotic cell cycle [GO:0000278]; negative regulation of BMP signaling pathway [GO:0030514]; negative regulation of cell-cell adhesion [GO:0022408]; negative regulation of cellular senescence [GO:2000773]; negative regulation of endothelial cell apoptotic process [GO:2000352]; negative regulation of ERK1 and ERK2 cascade [GO:0070373]; negative regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043124]; negative regulation of long-term synaptic potentiation [GO:1900272]; negative regulation of mitotic cell cycle [GO:0045930]; negative regulation of phospholipase C activity [GO:1900275]; negative regulation of protein serine/threonine kinase activity [GO:0071901]; negative regulation of ubiquitin-protein transferase activity [GO:0051444]; neural tube closure [GO:0001843]; neuroepithelial cell differentiation [GO:0060563]; neuromuscular process controlling balance [GO:0050885]; neuropilin signaling pathway [GO:0038189]; peptidyl-tyrosine autophosphorylation [GO:0038083]; peptidyl-tyrosine phosphorylation [GO:0018108]; platelet-derived growth factor receptor-beta signaling pathway [GO:0035791]; positive regulation of actin cytoskeleton reorganization [GO:2000251]; positive regulation of actin filament binding [GO:1904531]; positive regulation of apoptotic process [GO:0043065]; positive regulation of blood vessel branching [GO:1905555]; positive regulation of cell migration involved in sprouting angiogenesis [GO:0090050]; positive regulation of cytosolic calcium ion concentration [GO:0007204]; positive regulation of endothelial cell migration [GO:0010595]; positive regulation of ERK1 and ERK2 cascade [GO:0070374]; positive regulation of focal adhesion assembly [GO:0051894]; positive regulation of I-kappaB kinase/NF-kappaB signaling [GO:0043123]; positive regulation of interferon-gamma production [GO:0032729]; positive regulation of interleukin-2 production [GO:0032743]; positive regulation of microtubule binding [GO:1904528]; positive regulation of mitotic cell cycle [GO:0045931]; positive regulation of muscle cell differentiation [GO:0051149]; positive regulation of neuron death [GO:1901216]; positive regulation of osteoblast proliferation [GO:0033690]; positive regulation of oxidoreductase activity [GO:0051353]; positive regulation of peptidyl-tyrosine phosphorylation [GO:0050731]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of release of sequestered calcium ion into cytosol [GO:0051281]; positive regulation of stress fiber assembly [GO:0051496]; positive regulation of substrate adhesion-dependent cell spreading [GO:1900026]; positive regulation of transcription by RNA polymerase II [GO:0045944]; positive regulation of Wnt signaling pathway, planar cell polarity pathway [GO:2000096]; post-embryonic development [GO:0009791]; protein autophosphorylation [GO:0046777]; protein phosphorylation [GO:0006468]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of actin cytoskeleton reorganization [GO:2000249]; regulation of apoptotic process [GO:0042981]; regulation of autophagy [GO:0010506]; regulation of axon extension [GO:0030516]; regulation of Cdc42 protein signal transduction [GO:0032489]; regulation of cell adhesion [GO:0030155]; regulation of cell motility [GO:2000145]; regulation of endocytosis [GO:0030100]; regulation of extracellular matrix organization [GO:1903053]; regulation of hematopoietic stem cell differentiation [GO:1902036]; regulation of microtubule polymerization [GO:0031113]; regulation of modification of synaptic structure [GO:1905244]; regulation of response to DNA damage stimulus [GO:2001020]; regulation of T cell differentiation [GO:0045580]; regulation of transcription, DNA-templated [GO:0006355]; response to oxidative stress [GO:0006979]; signal transduction in response to DNA damage [GO:0042770]; spleen development [GO:0048536]; substrate adhesion-dependent cell spreading [GO:0034446]; T cell receptor signaling pathway [GO:0050852]; thymus development [GO:0048538]; transitional one stage B cell differentiation [GO:0002333] actin filament binding [GO:0051015]; actin monomer binding [GO:0003785]; ATP binding [GO:0005524]; bubble DNA binding [GO:0000405]; DNA binding [GO:0003677]; ephrin receptor binding [GO:0046875]; four-way junction DNA binding [GO:0000400]; kinase activity [GO:0016301]; magnesium ion binding [GO:0000287]; manganese ion binding [GO:0030145]; mitogen-activated protein kinase binding [GO:0051019]; neuropilin binding [GO:0038191]; nicotinate-nucleotide adenylyltransferase activity [GO:0004515]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; phosphotyrosine residue binding [GO:0001784]; proline-rich region binding [GO:0070064]; protein C-terminus binding [GO:0008022]; protein kinase activity [GO:0004672]; protein kinase C binding [GO:0005080]; protein tyrosine kinase activity [GO:0004713]; sequence-specific double-stranded DNA binding [GO:1990837]; SH2 domain binding [GO:0042169]; SH3 domain binding [GO:0017124]; syntaxin binding [GO:0019905]; transcription coactivator activity [GO:0003713]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] GO:0000278; GO:0000287; GO:0000400; GO:0000405; GO:0001784; GO:0001843; GO:0001922; GO:0001934; GO:0002322; GO:0002333; GO:0003677; GO:0003713; GO:0003785; GO:0004515; GO:0004672; GO:0004713; GO:0004714; GO:0004715; GO:0005080; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0005739; GO:0005829; GO:0006298; GO:0006355; GO:0006464; GO:0006468; GO:0006897; GO:0006914; GO:0006974; GO:0006975; GO:0006979; GO:0007050; GO:0007173; GO:0007204; GO:0007229; GO:0008022; GO:0008630; GO:0009791; GO:0010506; GO:0010595; GO:0015629; GO:0016301; GO:0016604; GO:0017124; GO:0018108; GO:0019905; GO:0021587; GO:0022408; GO:0030035; GO:0030036; GO:0030100; GO:0030145; GO:0030155; GO:0030425; GO:0030514; GO:0030516; GO:0031113; GO:0031252; GO:0031965; GO:0032489; GO:0032729; GO:0032743; GO:0032956; GO:0032991; GO:0033690; GO:0034446; GO:0034599; GO:0035791; GO:0038083; GO:0038096; GO:0038189; GO:0038191; GO:0042169; GO:0042770; GO:0042981; GO:0043025; GO:0043065; GO:0043123; GO:0043124; GO:0043542; GO:0045184; GO:0045580; GO:0045930; GO:0045931; GO:0045944; GO:0046632; GO:0046777; GO:0046875; GO:0048471; GO:0048536; GO:0048538; GO:0048668; GO:0050731; GO:0050798; GO:0050852; GO:0050853; GO:0050885; GO:0051015; GO:0051019; GO:0051149; GO:0051281; GO:0051353; GO:0051444; GO:0051496; GO:0051882; GO:0051894; GO:0060020; GO:0060563; GO:0070064; GO:0070301; GO:0070373; GO:0070374; GO:0071103; GO:0071222; GO:0071901; GO:0072359; GO:0090050; GO:0090135; GO:0098794; GO:1900026; GO:1900272; GO:1900275; GO:1901216; GO:1902036; GO:1903053; GO:1903351; GO:1904528; GO:1904531; GO:1905244; GO:1905555; GO:1990051; GO:1990837; GO:2000096; GO:2000145; GO:2000249; GO:2000251; GO:2000352; GO:2000773; GO:2001020 PF08919;PF07714;PF00017;PF00018; IPR033221;IPR035837;IPR015015;IPR011009;IPR000719;IPR017441;IPR001245;IPR000980;IPR036860;IPR036028;IPR001452;IPR008266;IPR020635; 8 Q9P206 Uncharacterized protein KIAA1522 Homo sapiens (Human) GTQRLCGR cell differentiation [GO:0030154] GO:0030154 9 P61313 60S ribosomal protein L15 (Large ribosomal subunit protein eL15) Homo sapiens (Human) GQIFSRSA A band [GO:0031672]; cytosol [GO:0005829]; cytosolic large ribosomal subunit [GO:0022625]; cytosolic ribosome [GO:0022626]; membrane [GO:0016020]; nucleus [GO:0005634]; ribosome [GO:0005840] cytoplasmic translation [GO:0002181]; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [GO:0000184]; response to ethanol [GO:0045471]; rRNA processing [GO:0006364]; SRP-dependent cotranslational protein targeting to membrane [GO:0006614]; translation [GO:0006412]; translational initiation [GO:0006413]; viral transcription [GO:0019083] cadherin binding [GO:0045296]; RNA binding [GO:0003723]; structural constituent of ribosome [GO:0003735] GO:0000184; GO:0002181; GO:0003723; GO:0003735; GO:0005634; GO:0005829; GO:0005840; GO:0006364; GO:0006412; GO:0006413; GO:0006614; GO:0016020; GO:0019083; GO:0022625; GO:0022626; GO:0031672; GO:0045296; GO:0045471 PF00827; IPR024794;IPR000439;IPR020925;IPR012678; 9 Q9Y689 ADP-ribosylation factor-like protein 5A Homo sapiens (Human) GGGDGAAF trans-Golgi network [GO:0005802] intracellular protein transport [GO:0006886]; protein localization to Golgi membrane [GO:1903292]; vesicle-mediated transport [GO:0016192] GTP binding [GO:0005525] GO:0005525; GO:0005802; GO:0006886; GO:0016192; GO:1903292 PF00025; IPR027417;IPR005225;IPR006689; 9 Q9P2G1 Ankyrin repeat and IBR domain-containing protein 1 (EC 2.3.2.31) Homo sapiens (Human) GHALCVCS cytoplasm [GO:0005737]; ubiquitin ligase complex [GO:0000151] positive regulation of proteasomal ubiquitin-dependent protein catabolic process [GO:0032436]; protein polyubiquitination [GO:0000209]; ubiquitin-dependent protein catabolic process [GO:0006511] metal ion binding [GO:0046872]; ubiquitin conjugating enzyme binding [GO:0031624]; ubiquitin protein ligase activity [GO:0061630] GO:0000151; GO:0000209; GO:0005737; GO:0006511; GO:0031624; GO:0032436; GO:0046872; GO:0061630 PF00023;PF01485; IPR002110;IPR020683;IPR036770;IPR031127;IPR002867;IPR044066;IPR003903;IPR001841;IPR013083; 9 Q9NZU7 Calcium-binding protein 1 (CaBP1) (Calbrain) (Caldendrin) Homo sapiens (Human) GVRNCLYG cell cortex [GO:0005938]; cytoskeleton [GO:0005856]; extracellular space [GO:0005615]; Golgi membrane [GO:0000139]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886]; postsynaptic density [GO:0014069] negative regulation of protein import into nucleus [GO:0042308]; response to stimulus [GO:0050896]; visual perception [GO:0007601] calcium-dependent protein binding [GO:0048306]; calcium ion binding [GO:0005509]; enzyme inhibitor activity [GO:0004857]; nuclear localization sequence binding [GO:0008139] GO:0000139; GO:0004857; GO:0005509; GO:0005615; GO:0005856; GO:0005886; GO:0005938; GO:0007601; GO:0008139; GO:0014069; GO:0042308; GO:0048306; GO:0048471; GO:0050896 PF13499; IPR043582;IPR011992;IPR018247;IPR002048; 9 Q96FZ7 Charged multivesicular body protein 6 (Chromatin-modifying protein 6) (Vacuolar protein sorting-associated protein 20) (Vps20) (hVps20) Homo sapiens (Human) GNTTTKFR cytosol [GO:0005829]; endosome membrane [GO:0010008]; ESCRT III complex [GO:0000815]; extracellular exosome [GO:0070062]; late endosome membrane [GO:0031902]; membrane [GO:0016020]; multivesicular body [GO:0005771] endosomal transport [GO:0016197]; ESCRT III complex assembly [GO:1904902]; late endosome to vacuole transport via multivesicular body sorting pathway [GO:0032511]; macroautophagy [GO:0016236]; midbody abscission [GO:0061952]; mitotic metaphase plate congression [GO:0007080]; mitotic nuclear envelope reassembly [GO:0007084]; multivesicular body assembly [GO:0036258]; negative regulation of epidermal growth factor-activated receptor activity [GO:0007175]; nucleus organization [GO:0006997]; protein transport [GO:0015031]; regulation of protein catabolic process [GO:0042176]; vesicle budding from membrane [GO:0006900]; viral budding via host ESCRT complex [GO:0039702]; viral life cycle [GO:0019058] protein-containing complex binding [GO:0044877]; protein N-terminus binding [GO:0047485] GO:0000815; GO:0005771; GO:0005829; GO:0006900; GO:0006997; GO:0007080; GO:0007084; GO:0007175; GO:0010008; GO:0015031; GO:0016020; GO:0016197; GO:0016236; GO:0019058; GO:0031902; GO:0032511; GO:0036258; GO:0039702; GO:0042176; GO:0044877; GO:0047485; GO:0061952; GO:0070062; GO:1904902 PF03357; IPR005024; 9 Q13319 Cyclin-dependent kinase 5 activator 2 (CDK5 activator 2) (Cyclin-dependent kinase 5 regulatory subunit 2) (p39) (p39I) Homo sapiens (Human) GMKHSSRC cytoplasm [GO:0005737]; growth cone [GO:0030426]; membrane [GO:0016020]; neuron projection [GO:0043005]; plasma membrane [GO:0005886]; protein kinase 5 complex [GO:0016533] cerebellum development [GO:0021549]; hippocampus development [GO:0021766]; layer formation in cerebral cortex [GO:0021819]; neuron migration [GO:0001764]; positive regulation of calcium ion-dependent exocytosis [GO:0045956]; regulation of cyclin-dependent protein serine/threonine kinase activity [GO:0000079]; superior olivary nucleus maturation [GO:0021722] actin binding [GO:0003779]; cyclin-dependent protein serine/threonine kinase activator activity [GO:0061575]; lipid binding [GO:0008289] GO:0000079; GO:0001764; GO:0003779; GO:0005737; GO:0005886; GO:0008289; GO:0016020; GO:0016533; GO:0021549; GO:0021722; GO:0021766; GO:0021819; GO:0030426; GO:0043005; GO:0045956; GO:0061575 PF03261; IPR004944;IPR036915; 9 Q155Q3 Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1) Homo sapiens (Human) GNAAGSAE cytoskeleton [GO:0005856]; cytosol [GO:0005829]; focal adhesion [GO:0005925] canonical Wnt signaling pathway [GO:0060070]; cerebral cortex radially oriented cell migration [GO:0021799]; forebrain ventricular zone progenitor cell division [GO:0021869]; negative regulation of neuron differentiation [GO:0045665]; positive regulation of Wnt signaling pathway [GO:0030177]; regulation of actin cytoskeleton organization [GO:0032956]; regulation of microtubule cytoskeleton organization [GO:0070507] actin binding [GO:0003779]; gamma-tubulin binding [GO:0043015]; protein domain specific binding [GO:0019904] GO:0003779; GO:0005829; GO:0005856; GO:0005925; GO:0019904; GO:0021799; GO:0021869; GO:0030177; GO:0032956; GO:0043015; GO:0045665; GO:0060070; GO:0070507 PF00307;PF00778; IPR001715;IPR036872;IPR001158;IPR038207;IPR029800;IPR015506;IPR029071; 9 Q7L9B9 Endonuclease/exonuclease/phosphatase family domain-containing protein 1 Homo sapiens (Human) GNANGKDE anchored component of plasma membrane [GO:0046658]; plasma membrane [GO:0005886] DNA repair [GO:0006281]; intracellular receptor signaling pathway [GO:0030522]; positive regulation of cholesterol efflux [GO:0010875] DNA binding [GO:0003677] GO:0003677; GO:0005886; GO:0006281; GO:0010875; GO:0030522; GO:0046658 IPR004509;IPR036691;IPR003583;IPR010994; 9 O95466 Formin-like protein 1 (CLL-associated antigen KW-13) (Leukocyte formin) Homo sapiens (Human) GSTLGCHR bleb [GO:0032059]; cell cortex [GO:0005938]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; phagocytic vesicle [GO:0045335]; plasma membrane [GO:0005886] actin filament severing [GO:0051014]; cell migration [GO:0016477]; cortical actin cytoskeleton organization [GO:0030866]; regulation of cell shape [GO:0008360] actin filament binding [GO:0051015]; GTPase activating protein binding [GO:0032794]; small GTPase binding [GO:0031267] GO:0005829; GO:0005886; GO:0005938; GO:0008360; GO:0016020; GO:0016477; GO:0030866; GO:0031267; GO:0032059; GO:0032794; GO:0045335; GO:0051014; GO:0051015; GO:0070062 PF06367;PF06371;PF02181; IPR016024;IPR014767;IPR015425;IPR042201;IPR010472;IPR043592;IPR027657;IPR014768;IPR010473; 9 P03362 Gag-Pro-Pol polyprotein (Pr160Gag-Pro-Pol) [Cleaved into: Matrix protein p19 (MA); Capsid protein p24 (CA); Nucleocapsid protein p15-pro (NC') (NC-pro); Protease (PR) (EC 3.4.23.-); p1; Reverse transcriptase/ribonuclease H, p49 subunit (p49 RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Reverse transcriptase/ribonuclease H, p62 subunit (p62 RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)] Human T-cell leukemia virus 1 (strain Japan ATK-1 subtype A) (HTLV-1) GAYKYIQE viral nucleocapsid [GO:0019013] DNA integration [GO:0015074]; DNA recombination [GO:0006310]; establishment of integrated proviral latency [GO:0075713]; suppression by virus of host gene expression [GO:0039657]; viral entry into host cell [GO:0046718]; viral genome integration into host DNA [GO:0044826] aspartic-type endopeptidase activity [GO:0004190]; DNA binding [GO:0003677]; DNA-directed DNA polymerase activity [GO:0003887]; RNA binding [GO:0003723]; RNA-directed DNA polymerase activity [GO:0003964]; RNA-DNA hybrid ribonuclease activity [GO:0004523]; structural molecule activity [GO:0005198]; zinc ion binding [GO:0008270] GO:0003677; GO:0003723; GO:0003887; GO:0003964; GO:0004190; GO:0004523; GO:0005198; GO:0006310; GO:0008270; GO:0015074; GO:0019013; GO:0039657; GO:0044826; GO:0046718; GO:0075713 PF02228;PF00607;PF00552;PF02022;PF00075;PF00665;PF00077;PF00078;PF00098; IPR001969;IPR003139;IPR036989;IPR043502;IPR000721;IPR036862;IPR001037;IPR001584;IPR003308;IPR001995;IPR021109;IPR018061;IPR008916;IPR008919;IPR010999;IPR043128;IPR012337;IPR002156;IPR036397;IPR000477;IPR001878;IPR036875; 9 Q9BZQ8 Protein Niban 1 (Cell growth-inhibiting gene 39 protein) (Protein FAM129A) Homo sapiens (Human) GGSASSQL cytoplasm [GO:0005737]; cytosol [GO:0005829]; extracellular exosome [GO:0070062]; membrane [GO:0016020]; plasma membrane [GO:0005886] negative regulation of protein phosphorylation [GO:0001933]; positive regulation of protein phosphorylation [GO:0001934]; positive regulation of translation [GO:0045727]; response to endoplasmic reticulum stress [GO:0034976] GO:0001933; GO:0001934; GO:0005737; GO:0005829; GO:0005886; GO:0016020; GO:0034976; GO:0045727; GO:0070062 IPR026088; 9 Q9P032 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 (Hormone-regulated proliferation-associated protein of 20 kDa) Homo sapiens (Human) GNLISLIF mitochondrial inner membrane [GO:0005743]; mitochondrial membrane [GO:0031966]; mitochondrion [GO:0005739] mitochondrial respiratory chain complex I assembly [GO:0032981] calmodulin binding [GO:0005516] GO:0005516; GO:0005739; GO:0005743; GO:0031966; GO:0032981 PF06784; IPR009622; 9 O75167 Phosphatase and actin regulator 2 Homo sapiens (Human) GNLISTSC plasma membrane [GO:0005886]; platelet alpha granule membrane [GO:0031092] actin cytoskeleton organization [GO:0030036]; platelet degranulation [GO:0002576] actin binding [GO:0003779]; protein phosphatase inhibitor activity [GO:0004864] GO:0002576; GO:0003779; GO:0004864; GO:0005886; GO:0030036; GO:0031092 PF02755; IPR029991;IPR004018; 9 Q7L014 Probable ATP-dependent RNA helicase DDX46 (EC 3.6.4.13) (DEAD box protein 46) (PRP5 homolog) Homo sapiens (Human) GTVLSLSP Cajal body [GO:0015030]; fibrillar center [GO:0001650]; membrane [GO:0016020]; nuclear speck [GO:0016607]; nucleoplasm [GO:0005654]; nucleus [GO:0005634] mRNA splicing, via spliceosome [GO:0000398] ATP binding [GO:0005524]; hydrolase activity [GO:0016787]; RNA binding [GO:0003723]; RNA helicase activity [GO:0003724] GO:0000398; GO:0001650; GO:0003723; GO:0003724; GO:0005524; GO:0005634; GO:0005654; GO:0015030; GO:0016020; GO:0016607; GO:0016787 PF00270;PF00271; IPR011545;IPR014001;IPR001650;IPR027417;IPR000629;IPR014014; 9 Q9LYW5 Probable E3 ubiquitin-protein ligase LUL1 (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase LUL1) (Protein LOG2-LIKE UBIQUITIN LIGASE 1) (RING finger protein 370) Arabidopsis thaliana (Mouse-ear cress) GALVIRGI protein ubiquitination [GO:0016567] metal ion binding [GO:0046872]; ubiquitin protein ligase activity [GO:0061630]; ubiquitin-protein transferase activity [GO:0004842] GO:0004842; GO:0016567; GO:0046872; GO:0061630 IPR001841;IPR013083; 9 Q9NR22 Protein arginine N-methyltransferase 8 (EC 2.1.1.319) (EC 2.1.1.321) (Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4) Homo sapiens (Human) GGTQVKCL anchored component of the cytoplasmic side of the plasma membrane [GO:0098753]; plasma membrane [GO:0005886] histone methylation [GO:0016571]; peptidyl-arginine methylation [GO:0018216]; peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [GO:0019919]; protein homooligomerization [GO:0051260]; protein methylation [GO:0006479]; regulation of protein binding [GO:0043393] enzyme binding [GO:0019899]; histone-arginine N-methyltransferase activity [GO:0008469]; identical protein binding [GO:0042802]; protein-arginine omega-N asymmetric methyltransferase activity [GO:0035242]; protein-arginine omega-N monomethyltransferase activity [GO:0035241]; protein homodimerization activity [GO:0042803]; S-adenosyl-L-methionine binding [GO:1904047]; S-adenosylmethionine-dependent methyltransferase activity [GO:0008757] GO:0005886; GO:0006479; GO:0008469; GO:0008757; GO:0016571; GO:0018216; GO:0019899; GO:0019919; GO:0035241; GO:0035242; GO:0042802; GO:0042803; GO:0043393; GO:0051260; GO:0098753; GO:1904047 IPR025799;IPR029063; 9 Q91J24 Protein C4 (Protein L4) Beet curly top virus (strain California/Logan) (BCTV) GRESRHYR host cell plasma membrane [GO:0020002]; membrane [GO:0016020] viral process [GO:0016032] GO:0016020; GO:0016032; GO:0020002 PF01492; IPR002488; 9 O75716 Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK) Homo sapiens (Human) GNLFGRKK cytoplasm [GO:0005737]; cytosol [GO:0005829]; Golgi apparatus [GO:0005794]; nucleoplasm [GO:0005654]; perinuclear region of cytoplasm [GO:0048471]; plasma membrane [GO:0005886] protein autophosphorylation [GO:0046777] ATP binding [GO:0005524]; non-membrane spanning protein tyrosine kinase activity [GO:0004715]; protein serine/threonine kinase activity [GO:0004674]; protein serine kinase activity [GO:0106310]; protein threonine kinase activity [GO:0106311]; transmembrane receptor protein tyrosine kinase activity [GO:0004714] GO:0004674; GO:0004714; GO:0004715; GO:0005524; GO:0005654; GO:0005737; GO:0005794; GO:0005829; GO:0005886; GO:0046777; GO:0048471; GO:0106310; GO:0106311 PF00069; IPR011009;IPR000719;IPR008271; 9 Q84VQ1 SNF1-related protein kinase regulatory subunit beta-1 (AKIN subunit beta-1) (AKINB1) (AKINbeta1) Arabidopsis thaliana (Mouse-ear cress) GQTSVSTL plasma membrane [GO:0005886] carbohydrate metabolic process [GO:0005975]; fatty acid biosynthetic process [GO:0006633]; nitrate assimilation [GO:0042128] ATP binding [GO:0005524] GO:0005524; GO:0005886; GO:0005975; GO:0006633; GO:0042128 PF16561;PF04739; IPR032640;IPR006828;IPR037256;IPR013783;IPR014756;IPR043554;IPR037170;